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Antrolin (Nifedipine)

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Antrolin is used to treat high blood pressure or angina (chest pain). For high blood pressure: Antrolin works by relaxing and expanding the blood vessels. This makes the blood flow more easily and lowers blood pressure. Lower blood pressure reduces the strain on your heart. For angina: Antrolin works by relaxing and expanding the arteries supplying the heart. This allows more blood and oxygen to reach the heart and decreases the strain on it. Your angina attacks will be less severe and less frequent if there is less strain on the heart.

Other names for this medication:
Adalate, Adefin, Adipine, Amarkor, Anpect, Atanaal, Atenerate, Calchan, Cardicon, Cardipin, Carditas, Cardules, Chronadalate, Cobalat, Coral, Cordalat, Corotrend, Depin, Depine, Fenidina, Ficor, Lemar, Macorel, Marivolon, Menoprizin, Myogard, Nefelid, Nidicard, Nifangin, Nifcal, Nifebene, Nifecap, Nifecard, Nifecor, Nifed, Nifedel, Nifedipin, Nifedipress, Nifelat, Nifensar, Nifeslow, Nifestad, Nifezzard, Nifin, Nirena, Ospocard, Sidalat, Vasdalat, Viscard

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Adalat XL. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Antrolin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Antrolin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Type-2 calcium-dependent potassium (KCa) channels from mammalian brain, reconstituted into planar phospholipid bilayers, are modulated by ATP or ATP analogs via an endogenous protein kinase activity intimately associated with the channel (Chung et al., 1991). Since these proteins are known to be involved in the regulation of cell division, this study seeks information about their influence in regulating cell proliferation in the human corneal endothelium. Different nuclearity silver(I) complexes with novel tetracyano pendant-armed hexaazamacrocyclic ligands. (1982) in a rat model of chronic pain of nociceptive origin, namely polyarthritis. Predictors of left main or three-vessel disease in patients who have acute coronary syndromes with non-ST-segment elevation. Finally, an algorithm is proposed for those patients with obsessive compulsive disorder who fail to respond to an adequate trial with a potent SRI. These plasmids complemented well-characterized Salmonella typhimurium temperature-sensitive topoisomerase IV mutations, showing that the S.

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It is of interest that four patients with myoclonus epilepsy with ragged-red fibers and one patient with chronic progressive external ophthalmoplegia all showed qualitatively similar abnormal excretion of such urinary lipids. Providers of gynecologic care in Utah were surveyed to assess existing conditions, attitudes, and comfort levels regarding this population. The small-task condition resulted in higher on-task behavior for all participants and in higher work rate for four of the five participants. Alternatively, interactions among coexisting tumor subpopulations may contribute to the emergence of a malignant invasive primary solid tumor. Within the immunised host, they mimic the effect of live attenuated viral vaccines when continuously expressing the polypeptide in question.

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Experiences with the licorice juice preparation Caved-S in the treatment of ulcers of the gastrointestinal tract. Mutations affecting the RecF pathway of recombination (recF, recG, recJ, recN, recO, recQ, recR, ruvA, ruvC) were systematically introduced into two sets of strains: (a) uvrA and uvrA recA2020, (b) uvrA recBC sbcBC and uvrA recBC sbcBC recA2020. Stress reactivity in responder and non-responder hypertensives treated with verapamil and enalapril. Analysis of fifteen estrogen metabolites using packed column supercritical fluid chromatography-mass spectrometry. After cells in the depth filter matrix reached saturation, overgrown viable cells at a perfusion rate of 5/d or 6/d were continuously collected into waste medium at a density of 2-4 x 10(5) cells/mL, which resulted in stable operation at high perfusion rates, maintaining values of process parameters such as glucose/lactate concentration, pH, and dissolved oxygen concentration.

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Effect of atypical mycobacterial infection on the cell-mediated immunity induced by Mycobacterium bovis BCG in mice. Surgical excision of wide areas of the posterior pharyngeal wall may allow acceptable swallowing function in many patients. These parameters have a well-established relationship to prognosis, but, if they are to be applied for both clinical and research purposes, they must be assessed consistently. The effect of bivalve nephrotomy on renal function in patients with staghorn calculi. Here, we investigated the consequences of interaction between HIF-1alpha and Mdm2 under hypoxic conditions. Stimulation of lymph outflow and the prevention of complications in treating lymphedema of the lower extremities. Hypertension should not be treated early after ischaemic stroke. Reversal of severe FK506 side effects by conversion to cyclosporine-based immunosuppression. Influence of nutrition on cellular multiplication in the epithelium of zyrtec treatment sinus infection the glands of the small intestine after electrothermocoagulation of the tubero-infundibular region of the hypothalamus in the rat.

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