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Antara (Fenofibrate)

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Antara is a peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. Antara is indicated as adjunctive therapy to diet to reduce elevated LDL-C, Total-C, Triglycerides, and Apo B, and to increase HDL-C adults with primary hypercholesterolemia or mixed dyslipidemia. Antara is also indicated to treat adults with severe hypertriglyceridemia.

Other names for this medication:
Antara, Apteor, Catalip, Craveril, Docfenofi, Fenobeta, Fenocap, Fenofib, Fenofibrat, Fenofibrato, Fenofix, Fenoglide, Fenohexal, Fenox, Fibrafen, Fulcro, Grofibrat, Hyperchol, Lexemin, Lifibrat, Lipicard, Lipidil, Lipofen, Lipofene, Lipolin, Lofat, Lowlip, Minuslip, Normalip, Procetoken, Proctofene, Stanlip, Trolip, Versamid, Xafenor, Zumafib

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Also known as: Fenofibrate


TriCor (fenofibrate) belongs to a group of drugs known as "fibrates." It helps reduce cholesterol and triglycerides (fatty acids) in the blood. High levels of these types of fat in the blood are associated with an increased risk of atherosclerosis (clogged arteries).

TriCor is used along with a proper diet to help to treat high cholesterol and high triglyceride levels.

In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help TriCor work better include exercising, losing weight if overweight, and stopping smoking.


Antara can be taken once a day. Take Antara capsules orally with water at the same time every day, with food. If you are taking colestipol (such as Colestid) or cholestyramine (such as Questran) while using Antara you should take these medicines at least 1 hour after using Antara or 4-6 hours before using Antara. Follow low-fat diet, low-cholesterol. If you want to achieve most effective results do not stop taking Antara suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antara are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take TriCor if you are allergic to fenofibrate, or if you have:

severe kidney disease (or if you are on dialysis); liver disease; or gallbladder disease.

Do not breast-feed while using this medicine, and for at least 5 days after your last dose.

To make sure TriCor is safe for you, tell your doctor if you have ever had:

kidney disease; liver disease; or gallbladder problems.

Fenofibrate can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease, diabetes, or poorly controlled hypothyroidism (underactive thyroid).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

TriCor is not approved for use by anyone younger than 18 years old.

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mulatta aged 27 to 30 years revealed a mean RNA content of 16.8 pg for the prefrontal cortex and 33.5 pg for the subiculum. The effect of Sendai virus infection on the splenic primary plaque-forming cell (PFC) response to sheep RBC in 2 strains of mice, with contrasting susceptibility to Sendai viral pneumonia, was examined. Follow-up of the structure of patients treated at the Out-patient Department for Clinical Psychotherapy and Psychosomatic Disorders at the Psychiatric Clinic in Sarajevo. Maximum-likelihood analysis of the resultant data partitioned the bacteria into three genera. Comparison of the risk factors for the development and malignant degeneration of diffuse inflammatory and neoplastic lesions of the large intestine. Public experiences, knowledge and expectations about medical genetics and the use of genetic information. Large atrial appendage thrombus in the presence of severe mitral regurgitation: contradictory hemodynamics or expected findings.

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A deletion derivative of FruA lacking the C-terminal 437 amino acids was still functional and could hydrolyze beta-(2,6)- and beta-(2,1)-linked sugars, but with altered preference for substrates. From the electrophoretic pattern the GLO-molecule appears to consist of two subunits. peritoneal or deep inside the myometrial wall of the uterus and/or in the rectovaginal septum. Cells of Vibrio cholerae underwent rapid autolysis when suspended in media of low osmolarity under non-growing conditions. Projecting the estimated needs for internists in Oklahoma through the year 1990. Idiopathic epidural lipomatosis as a cause of pain and neurological symptoms attributed initially to radiation damage. Retroactive inhibition as a function of response-class similarity.

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Pseudomonas putida strain AJ and Ochrobactrum strain TD were isolated from hazardous waste sites based on their ability to use vinyl chloride (VC) as the sole source of carbon and energy under aerobic conditions. After 6 h of photocatalytic treatment the total genotoxicity was removed. 3 of the 5 muscle fibre types which are discriminated by immune histochemical methods could thus be analysed. At least two direct repeats of AGGTCA-like sequences with 4-base spacing (DR4) and five-base spacing (DR5), in previously identified bile acid response elements of the rat CYP7A1 were able to bind LXRalpha/RXRalpha and confer LXRalpha stimulation. Comparing those participants in Experiment 1 who chewed gum at the learning or the recall phases showed that chewing gum at initial learning was associated with superior recall. Resolution of symptoms in patients with community-acquired pneumonia treated on an ambulatory basis. In the aorta of 20-wk-old SHR, endothelium-dependent contractions to acetylcholine are observed only when the production of nitric oxide is prevented. Alpha- and beta-adrenergic receptors and their second messengers play an important role in brain neurotransmission. Twelve patients were studied with intermittent fundamental imaging and IHI after administration of 5 mL and 10 mL of contrast agent. Concomitant histochemical demonstration of histamine and catecholamines in enterochromaffin-like cells of gastric mucosa.

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1966.-Cystathionine has been shown to be a precursor of methionine biosynthesis in Escherichia coli and Aerobacter aerogenes. Influence of an oil containing equal amounts of six fatty acids on the composition of fecal lipids in cystic fibrosis. The etiologic relationship between disturbances in metabolism of amino acids and amines and hepatic coma was investigated by examining the effects of diets containing various mixtures of amino acids on brain amine metabolism in rats with a portacaval shunt, using a method for simultaneous analysis of amino acids and amines. Such rearrangements might account for in vivo endothelial cell alterations involved in age-associated vascular dysfunction. Following radioiodination the MAb retained their immunoreactivity and demonstrated a significantly higher in vitro binding with isolated M3-tumour cells as compared with a control antibody. Our observations support the hypothesis that the FZD4-associated FEVR might represent a milder form than that associated with other genetic origins. Insulin-like growth-factor-binding proteins (IGFBPs) constitute a family of structurally related proteins that specifically bind insulin-like growth factors and modulate their functions. Other intrathyroidal neuropeptides, such as substance P and CCK-4, have been found to be without effects on iodothyronine secretion, but, like VIP, to stimulate calcitonin secretion. The single patients were diagnosed at a significantly earlier age and their general health scores were poorer than the married patients.

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This operation eliminates sensory input from both the olfactory and the vomeronasal systems. These analyses demonstrate that the rejection algorithm provides accurate estimates of Nebm across a broad range of demographic scenarios, except when the true Nebm is high. The analysis within nucleation theory emphasizes the important role of metal oxide as a heterogeneous nucleation site controlling the phase selection. This study described the clinical, surgical, and radiographic findings of simple bone cysts. Tilt analysis of pleomorphic vesicles in the superficial layers of the superior colliculus of Galago and chimpanzee. As an example, we apply the model to the Glanville fritillary butterfly (Melitaea cinxia) inhabiting a highly fragmented landscape. It is felt that with careful attention to the criteria which was used to decide on the choice of surgical technique, the results obtained by the non-drainage method should be as good in the more complicated case as they have already been shown to be in the primary case. CT (6 patients) and MRI (19 patients) were retrospectively reviewed. Interferon and adrenocorticotropic hormone induction of steroidogenesis, melanogenesis and antiviral activity.

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Moreover, the phenotypic expression of hereditary hemochromatosis is influenced by sex and environmental agents such as alcohol and dietary iron intake. Radioalkylation and analysis of V8-derived IL-1ra peptides indicate that the four cysteines present in the IL-1ra are not disulphide-linked. Outpatient laparoscopic radical hysterectomy is feasible and can be performed safely in a developing country in well-selected patients. Stability studies indicated that the formulations stored at refrigeration and room temperature showed no noticeable differences in the drug content and release profiles in vitro, after a period of 4 weeks. In this mini review the immune processes which cause rejection for each of these categories is described.

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Mirex incorporation in the environment: phytotoxicity on germination, emergence, and early growth of crop seedlings. The management of patients with metastatic cancer from an unknown primary site. Implant infections very often require complicated revision procedures that are troublesome to patients and costly to the healthcare system. Mechanisms of improvement in exercise capacity using a rollator in patients with COPD. The distribution of palmitoyl-CoA between bulk and surface phases can be described by a Langmuir adsorption isotherm with an equilibrium constant of 0.33 muM.

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Upon intragastric instillation, all test solutions, namely 3M and 5M ethanol (3330 and 5590 mosmol/kg resp.), 3M glucose (3890 mosmol/kg), 1.5 M choline chloride (2840 mosmol/kg) and 20 mM acetylsalicylic acid, also containing 100 mM HCl and 50 mM NaCl, produced macroscopic and microscopic lesions of the gastric mucosa. Proton pumping across the membrane was detected with either H2O2 or oxygen as terminal electron acceptor. When tumors from these animals were cultured in vitro, the culture supernatant fluid from drug-treated animals showed lower levels of PGE released into the media, but after several days in culture, tumor cells from indomethacin-treated animals fully recovered their ability to produce PGE. Substance P in the argentaffin carcinoid of the caecum: biochemical and biological characterization. After reaching maximal levels at 15 days of age, the total activity declined with the loss of activity occurring primarily in the ileum. High-grade GEP-NETs are neoplasms with exponentially increasing in incidence. In contrast, synthesis of all the virus proteins is equally inhibited in proportion to the interferon concentration used to treat the cells.

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In addition, the combination of KL with IL-11 also stimulated highly proliferative erythroid progenitors that yield remarkable macroscopic erythroblast colonies in culture. Thus, these interconnections may play some role in association of taste-related cognitive processes with feeding behavior. Extracorporeal membrane oxygenation in lambs through umbilical vessel perfusion: cardiac and hepatic complications. Electroretinographic and clinicopathologic correlations of retinal dysfunction in infantile neuronal ceroid lipofuscinosis (infantile Batten disease). Disposition and metabolism of intra-articularly injected 4-C14-cortisol in rheumatoid arthritis. Treatment with intramural methotrexate, delivered through a perforated balloon catheter at the selected concentration and total dose, failed to prevent intimal thickening after balloon injury. Monoclonal antibodies permitted detection of T-lymphocytes, suppressor-cytotoxic T-lymphocytes, helper-inducer T-lymphocytes, or B-lymphocytes. Three patients who underwent CABG showed severe myocardial ischemia resistant to intensive therapy with intravenous conventional vasodilators, including isosorbide dinitrate (ISDN), diltiazem, and nicorandil.

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The key fragments were 2a-c, 5c, 12b, 13b, 17, and 18 which were prepared via dianion ring cyclization, Friedel-Crafts acylation, and Reformatsky reaction. At 30 min after administration of the test meals, the stomach contents were completely aspirated and the volume, pH, phenol red concentration, total titratable acidity and different electrolytes were measured. Accurate detection of copy number alterations is necessary for discovering cancer-causing genes. Novel polysilanols by selective functionalizations of oligosilanes. These PB were found in the processes of nerve cells and astrocytes, but not in their perikarya. Mechanisms of acute increases in airway responsiveness caused by environmental chemicals. Experimental tissue lesions related to extracorporeal lithotripsy of gallbladder. HIV-infected patients with the MCP-1-2518G allele have a 5-fold increased risk for atherosclerosis, as assessed by ultrasonography. On day 19 of incubation, NDPase- and TPPase-positive cells with long, well-ramified cytoplasmic processes (well-ramified cells) were observed in the corpus striatum, these being mainly localized in the basal zone.

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NADPH-diaphorase activity which reveals the distribution of nitric oxide (NO) synthase in neurons was found to be intense in some dorsal root ganglion neurones and present at a lower level in the majority. Our aim was to design a low molecular weight synthetic molecule that potently and selectively blocks the VEGF/VEGF receptor system after oral administration, suitable for the chronic therapy of VEGF-dependent pathological neovascularization. Moreover, polymeric IgA (p-IgA) were not present, whereas in the immune response against viruses causing systemic infections, they are synthetised in large amounts. Imaging of iron oxide nanoparticles by MR and light microscopy in patients with malignant brain tumours. erythreus certain plasmid DNAs were present in both autonomous and chromosome-inserted states. Meanwhile functional genomics has evolved from several isolated technologies, such as DNA chip technology and proteomics, to combined approaches that can help us to understand why organisms produce a certain product.

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Fluorescent microscopic evaluation revealed heterogeneity in staining patterns of the antibodies on adherent cells. The First Direct Determination of a Ligand Binding Constant in Protein Crystals. Antibodies to the strain-specific and cross-reactive determinants of the haemagglutinin amoxil dosing peds of influenza H3N2 viruses. Uridine diphosphate-N-acetylglucosamine: lysosomal enzyme precursor N-acetyl-glucosamine-1-phosphate transferase, is a key enzyme involved in the intracellular targeting of lysosomal enzymes. The somatostatin infusion test for the evaluation of glucose utilization in bezafibrate medication. In the second experiment, 4 groups of 12 sheep were exposed to 100 ml saline every week or every two weeks, 100 mg chrysotile in 100 ml saline every week or every two weeks.

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Hypermethylation of the CDH1 promoter region was determined by methylation specific PCR following bisulphite modification, and compared with E-cadherin protein expression from a previous immunohistochemistry study. The optimum conditions for staining on polyacrylamide gels with this substrate were evaluated and compared with the staining method using N-gamma-L-glutamyl-alpha-naphthylamide as substrate. Growth effects of tranquilizing agents containing phenothiazine derivatives on barley seedlings-1. On the other hand, studies in vitro and in vivo have shown no changes in glutamate release during aging. Detection of cytomegalovirus by 24-well plate centrifugation assay using a monoclonal antibody to an early nuclear antigen and by conventional cell culture. Determination of blood loss during transurethral prostatic resection. Changes in the DNA methylation pattern influence atenolol medication type the DNA conformation.

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Mitotic figures, in which the long axis through the centers of the chromosome plates (chromatin masses) is perpendicular to the surface, are seen only occasionally. Several months after the initial injury, our patient remains short of breath and has difficulty breathing in the supine position. These results suggest that amygdala kindling does not alter activity of the NMDA receptor-channel complex modulating DA release in the striatum and amygdala. Quality of life for transplantation patients offers many opportunities for basic science and clinical researchers, ranging from biological and behavioral investigations to clinical interventions and population studies. Studies with scanning electron microscopy of cell surface alterations associated with invasiveness. To demonstrate the efficacy and long-term results of single-session ethanol sclerotherapy in symptomatic simple renal cysts in children. Severe anemia, defined as a hemoglobin level of less than 5.0 g/dL, affects millions of children worldwide. Their peripheral blood mononuclear cells showed an increased relative response (RR) to cells from HLA-identical siblings as compared to cells from normal HLA-identical siblings, confirming the results reported in an earlier series of 34 patients. Of the three life stages, the prereproductive, reproductive and postreproductive, only the prereproductive stage was significantly extended by vitamin E supplementation. Elicitation of an A48Id BL response required specific antigenic stimulation with either beta 2 leads to 6 or beta 2 leads to 1 fructosan epitopes, because it does not occur after injection with TNP-Ficoll in spite of the A48 treatment.

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As survival increases, rehabilitation professionals can anticipate a greater number of referrals for the assessment and management of physical disability in persons with HIV infection. Some reports have suggested that inflammation in perivascular adipose tissue (PVAT) may be implicated in vascular dysfunction by causing the disappearance of an anticontractile effect. Humans flexibly attend to features or locations and these processes are influenced by the probability of sensory events. Results showed that iron infusion increased carbonylation of plasma and urinary proteins in a time-dependent manner. Clinical practice guidelines on shared decision-making in the appropriate initiation of and withdrawal from dialysis. Cotransposition of a highly repetitive DNA element with flanking sequences in the genome of the midge Chironomus thummi. Light-dependent phosphorylation of C-terminal peptides of rhodopsin. Histomorphometric measurements were made from iliac crest biopsies of 32 women with vertebral fractures and 37 women without fracture. The up-regulation of actin, beta-actin and tubulin may play a key role in the motility and recruitment of microglia to the area of central nervous system inflammation.

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The former are managed in a fashion similar to the management of burns. Adenosine deaminase (ADA) activity was estimated in mucosal specimens obtained endoscopically from the duodenal bulb. Liposomal monensin remains in circulation for 2 h and was cleared from the blood stream after 4 h. Cyanohydroxybutene (CHB) is reported to be hepatotoxic in male Fischer 344 rats at an oral dose of 300 mg/kg and, while no longer hepatotoxic, pancreatotoxic at 200 mg/kg. Cervical lymphadenopathy from atypical mycobacteria: diagnosis and surgical treatment. The total RNA content in the individual nerve cells of the lumbal spinal ganglia in the dog after the 80 minutes lasting partial ischemia was followed. This will allow rapid identification of new variants that may arise and allow public health measures to be implemented accordingly.

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Hamster lung explants from both normal and bleomycin-exposed hamsters were cultured, and the effects of explant conditioned medium (CM) on lung fibroblast (IMR-90) proliferation and collagen production in vitro were determined. A 12-year-old boy with Shwachman syndrome had cutaneous involvement characterized by dry skin, perioral dermatitis, and follicular keratosis. The protective effect of Bcl-x(L) against death of these cells suggests a mitochondrial mechanism which is different from the antioxidant activity of Bcl-x(L). The prevalence, detection, and epidemiological correlates of peripheral vascular disease: a comparison of diabetic and non-diabetic subjects in an English community. Inhibitors of fatty acid cyclooxygenase such as indomethacin (0.1 mM), phenylbutazone (0.3 mM), and aspirin (1 mM) were found to suppress almost completely the interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung slices. Genetic model of some human hereditary diseases: features of behavior, neurochemistry and morphology of the brain in mice of the 101/HY line. The recommendations for delineation of the target volumes and organs at risk are detailed. PTH at 1 U/ml decreased the total amount of calcium and phosphorus, while LPSw did not.

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