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Angizem (Diltiazem)

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Angizem is a calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. It may also be used in hyperthyroidism if beta blockers cannot be used. It is taken by mouth or injection into a vein. When given by injection, effects typically begin within a few minutes and last a few hours.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Cozaar, Zithromax, Zudena, Rogaine, Duricef

Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Take Cardizem exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole.

Use Cardizem regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

You should not stop using Cardizem suddenly. Stopping suddenly may make your condition worse.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your blood pressure will need to be checked often. You may also need frequent blood tests.

Store Cardizem at room temperature away from moisture and heat.

Detailed Cardizem dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardizem LA dosage information

Side effects

The most common side effects associated with Angizem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


No information is available on the relationship of age to the effects of diltiazem in geriatric patients. However, elderly patients are more likely to have age-related kidney or liver problems, which may require an adjustment in the dose for patients receiving diltiazem.

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Fifteen patients who had such fractures were managed with open reduction and internal fixation and were followed for an average of twenty-five months (range, fourteen to forty-seven months). These injections lead to an increase of the cardiac output, to a decrease of the blood pressure, and hence cause a reduction of the resistance to blood flow. Patients in group A were given methoxamine 10 mg i.m., 15 min before spinal anaesthesia. The International Olympic Committee and the future hosting countries, including China, are encouraged to elaborate on this idea and offer the world a promising future for public health. The plasma method was calibrated from 1 to 5000 ng/mL in two ranges, with a limit of quantitation (LOQ) in the low range calculated at 3.3 ng/mL. The methods used in the early diagnosis of catheter malposition are compared in 31 patients with temporary endovenous pacemaker. Despite that, there was no significant difference in the initially achieved ACT in diabetics and non-diabetics. Stimulatory effects of cocaine and its metabolites on IM-9 human B-lymphoblastoid cells. The mechanism of the antitumoral effect of levan was studied in the C57BL mice-Lewis lung carcinoma system.

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There were many tumor vessels observed on the tumor surface, some of which bled subcapsularly. An examination of shipments of aquarium species arriving in Canada over a 2-year period revealed that one-third of the shipments of aquarium snails and aquarium frogs were contaminated with Salmonella. If this occurs, there is an increased probability of recurrent disease. Lactic dehydrogenase isozymes: variations in the plasma of men exposed to cold. While apical localization of PCP determinants such as Frizzled (Fz1) is critical for their function, the link between A/B polarity and PCP is poorly understood. ECHN honors cancer survivors with fun, food and inspirational stories. F4/80 is a monoclonal antibody that recognizes a murine macrophage-restricted cell surface glycoprotein and has been extensively used to characterize macrophage populations in a wide range of immunological studies. For 2 patients and 5 controls an equivocal result was obtained for IgG-ACA or IgM-ACA. This data supports further investigation of the chemopreventive and therapeutic potential of TS in tumors that are dependent on activated Ras signaling and identifies phosphor-Erk and phosphor-Akt as potential biomarkers of TS activity.

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Dietary zinc intake, zinc concentration in the serum and the ratio of apo/holo-activities of angiotensin converting enzyme (ACE), a zinc dependent enzyme in the serum (ACE ratio) were used as indices. The NBT staining in the renal and dermal vascular walls in both stages was significantly stronger than in the samples of control autopsy patients. Expression of a cell surface antigen recognized by the monoclonal antibody AUA1 in bladder carcinoma: an immunohistochemical study. Administration of 25-OHD3 is advisable in chronic hepatitis or cirrhosis accompanied by a defect of 25-hydroxylation and/or intestinal loss of the metabolite. Beta-2-microglobulin serum profiles in different settings of mass transport and fluid pyrogen content.

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To meet the increasing needs for food and energy for the growing population combined with the improvement of living standards, Nr will inevitably increase. The immediate early gene, junB, is induced by interleukin-6 (IL-6) in plasmacytomas. Interruption of the inferior vena cava is often associated with significant cardiovascular and abdominal anomalies but only rarely with anomalies of tracheobronchial branching. intermedius adheres extensively to both inflamed and noninflamed canine atopic skin. The data published by the beginning of January 2004 are summarized in this review.

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Minimal inhibitory concentrations of active compounds were determined. Hemoglobin synthesis in differentiated KU-812F/33 cells was analyzed by isoelectric focusing gel electrophoresis, and S1 mapping analysis of beta- and gamma-globin mRNA was performed. Resting energy expenditure and respiratory quotient (RQ) were assessed by indirect calorimetry at 0830, 1130 and 1430. Primary-response precipitins have the characteristics of macroglobulins. This study investigated whether a combined regimen of ipriflavone and 1 alpha vitamin D is effective in stopping postmenopausal bone loss. Follow up of patients with signs and symptoms of polyneuropathy not confirmed by electrophysiological studies. Heat shock factor-1 and nuclear factor-kappaB are systemically activated in human acute pancreatitis. The ability of PMNs to interact with ECM proteins and modulate ECM protein receptors suggests that these proteins, alone or in synergy with chemotactic peptides, play an important role in regulating PMN diapedesis.

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The authors used focus groups, key informant and other in-depth interviews, observations, a household survey, and tests of school children knowledge of malaria to gather social, cultural, and behavioral data associated with the acquisition, transmission, and prevention of malaria, and the diagnosis and treatment of disease in six villages of Heping Town and three production teams of Chengpo Farm, Qiongzhong County. The B apoprotein occurs in a wide range of plasma lipoproteins, which are heterogenous both with respect to size and to composition. Behavioral and learning disabilities associated with cognitive-motor dysfunction. Diagnosis is based on histological and immunohistochemical techniques. An explanation was given for the disaccord between antitumor and DNA photocleaving activities. Primary prevention of cardiovascular diseases today requires efficient programmes because they are forming the leading cause of death in majority of the countries where reliable mortality statistics are available.

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Identification of depression in the absence of verbal report on subjective mood state is a difficult task. Intracerebral haemorrhage due to amphetamine abuse: report of two cases with underlying arteriovenous malformations. The viruses are observed most frequently in intercellular spaces, but are also often found within cytoplasmic vacuoles of megakaryocytes. Since levels of cleaved caspase-3 and PARP, markers of apoptosis, were only elevated with lower doses, the observed cell death at supradose levels was probably due to necrosis. In total, eight mutations were present in the flanking regions of four loci. Powerful strategies to test candidate motifs include their ability to direct simpler reporter proteins, to which they are fused, to the appropriate cellular compartment. Mitogen-activated protein kinase (MAPK) is activated in many cell types in response to growth factors during the G0-G1 transition in the cell cycle. Defining the effectiveness of control measures was a part of this study and is the subject of this article. Only young rats showed tumor growth inhibition by calcitonin treatment.

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Public Health Service guidelines for management of occupational exposure to HIV and initiation of postexposure prophylaxis are discussed as well as World Health Organization recommendations for use of antiretroviral therapy in resource-limited settings. Compensators produced with computer controlled milling devices usually consist of a styrofoam mould, filled with an appropriate material. Immunohistochemical localization of transforming growth factor-beta 1 in growth plate freshly transplanted into a full-thickness defect in articular cartilage. This report supports the standard use of TBW-adjusted alcohol intakes in analyses of samples with both genders and/or a wide age range. The chondrocytes were isolated and multiplied in vitro, and then the chondrocytes were seeded onto the porous collagen/hydroxyapatite composite scaffold and were cultured in a three-dimensional environment for 3 weeks. Thermosensitive poly(organophosphazene) hydrogels for a controlled drug delivery. The impaired response of the autoreactive T cell clone to 2-day cultured monocytes could not be attributed to reduced expression of several well-defined surface molecules nor to induction of nonresponsiveness. Considerable evidence suggests that psychostimulants can exert rewarding and locomotor-stimulating effects via increased dopamine transmission in the ventral striatum. These data indicate that abdominal surgery induces thermal but not mechanical hyperalgesia in sheep, which appears to be centrally mediated.

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These studies demonstrate that human uvomorulin is differentially expressed in proliferative skin disorders, which may account at least in part for the differences observed in the clinical course between squamous cell and basal cell carcinoma. Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression. As a consequence, the Gene B protein is exposed on the parasite surface while other peptides are buried beneath the glycocalyx. coli peritonitis, MMP-9(-/-) mice showed much higher peritoneal chemokine and cytokine levels compared with wild-type mice. Our study is the first to examine simultaneously all key proteins involved in this pathway including TXA(2) receptors and results suggest that the TXA(2) pathway may be a potential target for PCa prevention/therapy. Dislocations were common at 111 N of compressive loading, while larger loads progressively stabilized the prosthesis. Repeat intracoronary beta-brachytherapy using a rhenium-188-filled balloon catheter for recurrent restenosis in patients who failed intracoronary radiation therapy. Furthermore, membrane translocation of alpha-synuclein was not significantly affected by treatment with inhibitors of endocytosis. Six patients with inferior and middle polar renal cysts of 8-15 centimeters of diameter, underwent the resection of the cyst by laparoscopic technique. RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

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Peak myocardial concentrations occurred simultaneously with the maximum decreases in myocardial contractility, except for the 100-mg doses. For the other half of the patients RA is a progressive and disabling disease. By transbronchial brushing cytology, several suspect cells with a papillary arrangement showing a high nuclear/cytoplasmic ratio, irregularity of nuclear shape, nuclear enlargement and a macronucleolus were obtained. Obviously the results might have been better if the time interval had calan medication been shorter. In addition, actual analysis was performed successively by our method using trial samples of matrix. Immunohistochemical detection of interstitial collagens in bone and cartilage tissue remnants in an infant Peruvian mummy. The heart was anatomically normal but complete heart block was present with a ventricular rate of 22bpm and atrial of 101bpm. Value of successive use of aldactone and aldactacine in the management of congestive heart failure involving at the outset hypokalemia with or without cardiac rhythm disorders. Addition of human chorionic gonadotropin to clomiphene citrate ovulation induction therapy does not improve pregnancy outcomes and luteal function.

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Several methods have been developed for the faithful reconstruction of surface models which represent the true cortical surface in both geometry and topology. Endoproteases activities are induced after bloodmeal and attain their maximum values between 10 and 36 h PBM. Carnitine supplementation in human idiopathic asthenospermia: clinical results. In normal ageing, neural function declined markedly while optical function remained essentially unchanged. Intense immunoreactivity was also localized in the outer layer of the zona radiata and the peripheral region of the ooplasm at the primary yolk globule stage. The availability of more medical information about the reasons for the sick leave episode does not modify the quality of the diagnosis substantially. The present study combined parallel data from the Northeast-Northwest Collaborative Adoption Projects (N2CAP) and the Western Reserve Reading Project (WRRP) to examine sibling similarity and quantitative genetic model estimates for measures of reading skills in 272 school-age sibling pairs from three family types (monozygotic twins, dizygotic twins, and unrelated adoptive siblings). Nitrite and nitrate content of foods sampled during national food quality monitoring. Understanding the complex pathophysiology of allergic diseases has been a main challenge of clinical and experimental research for when to stop differin gel many years. This unique case demonstrates that cryptococcal disease can be diagnosed antemortem by vitreous biopsy, and should be added to the differential diagnosis in cases of chronic smoldering uveitis.

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There is a strong relation between extra-intestinal, mental and somatic complaints and FGID in both patients and non-patients. Acoustic emission experiments on creeping ice as well as numerical simulations argue for a self-organization of collective dislocation dynamics during plastic deformation of single crystals into a scale-free pattern of dislocation avalanches characterized by intermittency, power-law distributions of avalanche sizes, complex space-time correlations and aftershock triggering. There were no significant differences in subjective quality of life or in readmissions during follow-up. Diagnostic and prognostic value of K39 recombinant antigen in Indian leishmaniasis. It is concluded that in the early stage of the fifth instar the cellular structures necessary for the biosynthesis of fibroin are rapidly formed, while in the later stage the biosynthesis of fibroin proceeds at a maximum rate and utilizes these structures. Declining mortality trends are seen in most populations, though in certain Eastern European countries, the declines began rather recently, during the 1980s.

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The patient developed blistering on the leg, then septic shock necessitating amputation. A method for separating, profiling, and quantifying the contributions of different structural components to expressive musical performance is described. In addition to maintenance drug treatment, behavior therapy and family counseling are usually indicated. Helical CT of the liver: evaluation of injection flow rate, mode, and scan delay with a reduced-volume contrast medium bolus. Experimental introduction of catgut into the anterior chamber of the eye in rabbits. The uptake of triiodothyronine by erythrocytes in pregnancy complicated by thyrotoxicosis.

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The magnetoelectrically induced P can be rotated 360 degrees by external B. From this comparison we conclude that hRPE do not respond to hypoxia with a general, nonspecific increase in the overall levels of growth factors, as is seen during cell wounding responses or serum stimulation. The latest vaccines for Respiratory Syncytial Virus (RSV) are reviewed. Dose response to cerebrospinal fluid avapro pill drainage on cerebral perfusion in traumatic brain-injured adults. cruzi showed no increased parasitemia or death upon treatment with L-NAME. The overexpression of p53 protein is uncommon in colorectal carcinoid tumors.

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Photopic and scotopic electroretinographic measurements were normal in all except two in whom the scotopic b wave was supernormal. The implications of this finding for future neuroethological studies are discussed. This perspective continues the debate, and offers a unique perspective from the vantage point of a uro-oncologist. Increasing incubation time only increased the optical density of NADPH-d staining, in contrast, the number of NADPH-d positive cells counted was relatively consistent across incubation times. In this multicentered, observer-blind study, healthy 15-20-month-old children previously immunized with three doses of Pentacel were randomly allocated to receive a single dose of Pentacel or Infanrix-IPV-Hib. Swedish otologists in the Skandinaviska Undervisningssjukhus in Korea. All calcium prerinses significantly increased the 1-hour saliva F relative to the NaF control without a prerinse. The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention released guidelines for the use of a tetravalent meningococcal conjugate vaccine in adolescents 11 years and older. A review of multidimensional separations such as comprehensive two-dimensional gas chromatography (GC x GC), comprehensive two-dimensional high performance liquid chromatography (HPLC x HPLC) and their applications in pharmaceutical and biological fields is presented with 71 references. We have illustrated a functional interaction between TRPC1 channels and RyR1 for the regulation of store-operated calcium entry (SOCE) initiated after releasing calcium from a caffeine-sensitive intracellular calcium pool.

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A factor analytic study of effectiveness criteria in intercollegiate athletics. This paper is an overview of cell culture models for antioxidant research, as reported at the First International Congress on Antioxidant Methods, held in Orlando, FL, June 16-18, 2004, and outlines potential cell culture models for initial antioxidant screening and antioxidant research. The patient was lipitor medication classification treated with INH, rifampin, and cycloserine with amelioration of clinical symptoms and return of serum alkaline phosphatase levels to normal. No vascularization on the surface of transplanted capillaries was observed in the absence of islets. Micronuclei and 3AB-index in patients receiving iodine-131 therapy. Intraoperative mapping studies suggest that an isthmus of myocardium between the mitral valve annulus and the border of inferior myocardial infarction may play a role in the genesis of ventricular tachycardia. Patients were treated with celecoxib 400 mg orally twice a day for 12 months. These programs, although targeting the adolescent population, differ in educational process based on the delivery setting. The paper further reports that GFP can be detected in intact tissues after delivering the constructs into Arabidopsis leaf and root by microprojectile bombardment.

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Echo-volumar imaging (EVI) of the brain at 3.0 T: first normal volunteer and functional imaging results. Clinical usefulness of helical-scanning CT for the evaluation of arteriosclerotic carotid lesions. The lesion was characterized by an influx of lymphocytes and the presence of fibroblasts and epithelioid cells. Empirical equations that relate extrapolation factors to chemical log K(ow) are given to facilitate the incorporation of metabolism data into bioconcentration and bioaccumulation models. The effect of low concentrations of estradiol and testosterone on the gonadal differentiation of Salmo trutta L. The contributions that can be made by evaluation procedures to the definition of mental health policies and to overcome mental health service deficiencies are stressed.

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The concentrations of dehydroepiandrosterone (DHEA), pregnenolone (PREG), allopregnanolone (AP), dehydroepiandrosterone sulfate (DS) and pregnenolone sulfate (PS) in nucleus accumbens (Nac), hypothalamus (Ht), amygdale (A) and plasma of rats were determined with liquid chromatography-negative atmospheric pressure ionization mass spectrometry (LC-MS). Cell transplantation is emerging as a novel approach for the treatment of end-stage cardiac disease. Rising costs in establishing and running dialysis clinics and the lost of nephrologic procedures previously performed by nephrologists are among the chloromycetin antibiotic side effects many reasons for this disillusionment with the specialty. Functional reorganization of language in a case of cortical development disorder with continuous spike and wave during sleep. The combination of a single dose of razoxane (ICRF 159) with a single dose of electron radiation has been studied with the murine sarcoma S180. Most of the fibres to which workers are exposed are short and thin. This was done using estimates of variation in two indicators: proportional infant mortality and the coefficient of infant mortality. HEp-2 was sensitive to DON showing cell death after 2 days (100 ng ml(-1)) with complete cell death occurring at 200 ng ml(-1) after 4 days of exposure. One hundred fifty-nine patients with mild to moderate essential hypertension were enrolled.

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