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Angioten (Losartan)
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Angioten

Angioten is a hypertension treatment. Research suggests that the medication is safe and effective for most people. People may experience mild side effects, such as dizziness, in the early stages of treatment. People who experience severe or persistent side effects should contact their doctor right away.

Other names for this medication:
Arapres, Cormac, Corus, Covance, Faxiven, Fensartan, Hizaar, Insaar, Lepitrin, Lopernal, Losacor, Losagen, Losamet, Losap, Losargamma, Losartas, Losartax, Losatrix, Losazide, Lostan, Lotan, Loxibin, Lozatan, Medzar, Osartil, Psycholanz, Sarilen, Sarve, Temisartan

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Also known as: Losartan

Description

Angioten (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Angioten is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Angioten is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Angioten 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Angioten 25 mg, Angioten 50 mg, and Angioten 100 mg may also contain carnauba wax.

Dosage

Take Angioten tablets orally with or without food. Do not crush or chew it. Take Angioten once or twice a day at the same time. If you want to achieve most effective results do not stop taking Angioten suddenly.

Overdose

If you overdose Angioten and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Angioten overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Angioten are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Angioten as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Angioten. Correct volume or salt depletion prior to administration of Angioten.

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Watery diarrhea ceased and pneumonia associated with massive endotracheal aspirates was reduced. Seven patients with intractable diarrhea were found to be excreting large quantities of chloride in the stool, associated with metabolic alkalosis, hyponatremia, hypokalemia, hypochloremia, and the excretion of chloride-free urine. Estimates of LVWV in patients with large wall volumes are less accurate. It is now widely recognized that aberrant platelet aggregation induced primarily by thrombin, rather than plasmin, is one of the major causes of recurrent thrombosis following pharmacologic thrombolysis. The identification of a naturally occurring cell surface growth inhibitor related to a previously described bovine sialoglycopeptide. Inhibitory effect of 9-(2-phosphonylmethoxyethyl)-adenine (PMEA) on human and duck hepatitis B virus infection. Time-out and the characteristics of mentally retarded institutionalized adults who do or do not receive it. Free estradiol in serum and brain uptake of estradiol during fetal and neonatal sexual differentiation in female rats.

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Immunoprecipitation demonstrated secretion of both isoforms, MCP-1 alpha and -beta, of the MCP-1 protein. When this pleiotropic mutant was inoculated on roots or stems of the host, no nodules developed (Nod-). Broad-spectrum cephalosporins including cefepime and cefpirome are hydrolysed by ESBL. A new theory which describes raster charge-up for highly insulating specimens is presented. Thus, they provide a positive marker that distinguishes the solitary fibrous tumor from most elements in the differential diagnosis. Touch perception thresholds in blind diabetic subjects in relation to the reading of Braille type. While co-activation stimuli can be achieved either with immobilized natural ligands or immobilized monoclonal antibodies specific for various integrin subunits, counterposing effects can be delivered by ligation of the integrin beta 1 chain (CD29) resulting in the downregulation of T cell proliferation. Toxicity quantitative structure--activity relationships of colchicines. By external bleeding the arterial pressure was lowered to 40mmHg and held for 30min.

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The formal tests were the Hospital Anxiety and Depression Scale (HADS) for psychological status, and the Rotterdam Symptom Checklist (RSCL) and Spitzer QL-Index for quality-of-life assessment. Inactivation of the HIF-alpha binding partner, arylhydrocarbon receptor nuclear translocator (Arnt), but not Hif-1alpha, suppressed the development of renal cysts. The maltose-binding protein-VirB11 fusion was able to complement a virB11 deletion mutant of A. We aimed to investigate if this was the case with losartan when compared to atenolol. We conclude that the main reason for the occurrence of certain serum proteins in the intestinal juice is a selective passage through the capillary wall followed by passive intercellular transport via delivery of the serum in the interstitial space during disintegration of the enterocytes. Immunohistochemical studies showed that the expression of HAM.4 antigen in hepatocytes and bile duct cells was not altered appreciably after bile duct ligation even when HAM.4 antigen in serum reached a maximal level.

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The problem of a possible trans-species inheritance of C4d polymorphism was addressed and two apparently contradicting dendrograms were obtained. Effect of uremia, uremic toxin and hypothermia on the electrical activity of the brain in animal experiments. We found a significant association between patient satisfaction and the performance of some but not all preventive care services. Neuronal dynamics of bottom-up and top-down processes in area V4 of macaque monkeys performing a visual search. In this case report a patient with a large intraventricular benign ependymoma is presented. In vitro testing of six inferior vena cava filters: filtering efficiency and pressure measurements. The biotinylated pRS47/BamHI insert probe was tested on 3 dilutions of DNA extracted from 3 strains of R. Endocrinological studies revealed low levels of free thyroid hormone with an inappropriately low level of thyroid-stimulating hormone that responded to bolus injection of thyrotropin-releasing hormone with a normal but somewhat delayed pattern.

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Correlation of different excitatory and inhibitory influences on cells in the nucleus gracilis of the cat. Assessing performance of cow-calf operations using epidemiology. It is essential to diagnose rare but serious conditions such as epidural abscess, tuberculosis, or opportunistic infections in patients at risk. Dehydroepiandrosterone sulfate (DHEAS) blocked the GABAA receptor noncompetitively in neurons grown in primary culture from the ventral midbrains of fetal rats. Detection of amino acids on the agretopes of pigeon cytochrome c derived peptide p43-58 specifically bound to mouse MHC class II allelic products. Magnetisation transfer ratios and transverse magnetisation decay curves in optic neuritis: correlation with clinical findings and electrophysiology. Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment.

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hst-1/int-2 co-amplification is closely related to the metastatic potential of esophageal carcinomas. The SOLVD treatment trial showed a highly significant improvement in survival on enalapril in comparison with placebo. In both trials, patients on fluvoxamine complained of a variety of adverse effects, which they often identified as the basis for early termination of treatment. Rat pancreatic islet pretreatment with anti-MHC class II monoclonal antibodies and culture: in vitro MLIC test response does not predict islet allograft survival. Biogenesis of the posterior-tail plasma membrane domain of the mammalian spermatozoon: targeting and lateral redistribution of the posterior-tail domain-specific transmembrane protein CE9 during spermiogenesis. The blood/gas partition coefficients in 24 horses showed a significant dependence on plasma triglyceride concentration (regression coefficient 0.00084 (SEM 0.00033) per mg dl-1), an insignificant positive dependence on plasma free and total cholesterol concentration and, in a multiple regression analysis, a negative dependence of borderline significance on packed cell volume (regression coefficient -0.01 (SEM 0.005) per per cent p.c.v.).

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Analysis of tests for diabetes in 250,000 persons screened for diabetes using finger blood after a carbohydrate load. The latter is indicated, despite of the scarcity of data, when longer lasting and severe affective symptoms emerge. The action of alkalis and acids in the conversion of collagen into eucollagen. The N-terminal 19-amino acid segment of Rex has been identified as the nucleolar targeting signal (NOS) and shown to be important for Rex function. 2 cases of the syndrome of premature aging in children (progeria and progeroid). Development of a scoring system to assess disability in an Italian elderly population. Drainage and/or antibiotic therapy may allow surgery to be avoided in these patients. Effect of repeated doses of hydroflumethiazide on renal excretion of electrolytes and uric acid in healthy subjects. These achievements are of particular interest because the general strategy of malaria eradication in the USSR has many technical, administrative, and economic and social features not seen elsewhere. At initial infection, EBV virion glycoproteins gp350 and gp220 bind to CD21.

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A skin biopsy specimen from an EN lesion showed lobular and septal pannicular infiltration by atypical lymphocytes. However, as laronidase does not cross the blood-brain barrier it will probably not influence the central nervous manifestations in the most severely affected patients with the Hurler phenotype, although it may improve general lung and heart function, making bone marrow transplantation easier to tolerate. Medical and surgical management of hernia through the esophageal hiatus in children. Alpha-subunit and human chorionic gonadotropin-beta immunoreactivity in patients with malignant endocrine gastroenteropancreatic tumours. In cluster 11, where signals for AST-like peptide are absent, a number of interneurons express both decapod-TRP and orcokinin, emphasizing a close relationship between these two factors with regard to olfactory processing, and possibly tactile and/or visual sensory systems. The effect of urban socioeconomic problems on perinatal statistics in Milwaukee, 1983-1991. Black raspberry extract and fractions contain angiogenesis inhibitors. Calcium- and magnesium-induced fusion of mixed phosphatidylserine/phosphatidylcholine vesicles: effect of ion binding. Two biopsy specimens from antrum, body, and fundus were taken for histology and search for H.

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In situ hybridizations with 35S labeled antisense RNA probes were performed on prazosin 1 mg side effects head serial frontonasal sections, as well as entire embryo and postnatal tail longitudinal sections. 4-Phenylbutyrate (4-PBA) is an oral butyrate derivative that has recently been approved for treatment of urea cycle disorders and is under investigation in clinical trials of cancer, hemoglobinopathies, and cystic fibrosis (CF). We also performed S1P1 immunohistochemistry analysis in synovial tissue from 28 RA patients and 18 osteoarthritis (OA) patients. In the reticular part of the dermis, shaving alone induced angiogenesis peaking at day 14, concomitant with hair regrowth. In laboratory investigations no adverse results were encountered. The absorbance spectrum of the intact fimbriae was consistent with that of a nucleoprotein. Two hundred and fifty-eight patients with pathologically proved periampullary carcinomas who underwent surgical treatment between the years 1965 and 1992 were evaluated.

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Changes in peroxisome proliferator-activated receptor gamma coactivator flagyl 2g dose kinetics -1 preceded those of nuclear respiratory factor-1 and nuclear respiratory factor-2, suggesting that it may be the prime sensor of neuronal activity and its energy demand. Patients receiving sorbitol demonstrated improvement in all psychomotor tests, whereas similar patients not receiving sorbitol showed no improvement. The beneficial effects of special care units vary among patients, and they decrease over time. Phylogeny of Helicobacter isolates from bird and swine feces and description of Helicobacter pametensis sp. Antagonism of the anti-thrombotic effect of warfarin by uric acid. A gene selection method searches for an optimal or near optimal subset of genes with respect to a given evaluation criterion.

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Percent changes in MBP, TPRI and CI were not different between SHR and WKY. Interleukin-2 and interferon-alpha-2a outpatient therapy for metastatic glucotrol xl tab 10mg renal cell carcinoma. A computerized search was performed of MEDLINE, Cochrane database, EMBASE, and reference lists of pertinent review articles for prospective randomized trials in adult patients with acute pancreatitis that evaluated interventions with nutrition therapy. Because all the dissolved substances with molecular weight (mol. Collectively, our data indicate that VGLUT3 identifies a novel excitatory terminal subset that contributes to the tuning of DA cell excitability in the substantia nigra. In contrast, the differentiation of N103 cells by IL-6 was not affected by L-NG-monomethylarginine. Aortic stent-graft infection following septic complications of a kidney stone. The aim of the present study was to investigate the role of NO in the hindquarter vasodilation in response to hypothalamic stimulation.

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