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Anegyn (Metronidazole)
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Anegyn

Anegyn is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

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Also known as: Metronidazole

Description

Anegyn (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Anegyn is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to con- tinue the seven-day regimen. A seven-day course of treatment may minimize reinfection by pro- tecting the patient long enough for the sexual con- tacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regi- men better than the other.

Overdose

Single oral doses of Anegyn, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Anegyn has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Anegyn overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store below 77 degrees F (25 degrees C) and protect from light.

Side effects

The most common side effects associated with Anegyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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In addition, IL4 inhibited the IL6-induced production of haptoglobin although it had no effect on the induced C-reactive protein and fibrinogen. Effects of temperature and cholesterol on the glucose permeability of liposomes prepared with natural and synthetic lecithins. Overnight storage of the porcine isolated splenic artery enhances endothelium-dependent contractions to NG-nitro-L-arginine methyl ester without impairing endothelium-dependent dilator function. Human astrocyte cultures showed decreased expression of glial fibrillary acidic protein (GFAP), as well as the diminution of a major protein of 66 kDa. A tentative pathway for the degradation of homophthalate is proposed based on isolation of intermediates, oxygen uptake studies and presence of enzymes involved in the degradation.

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Cell-mediated immunity to Toxoplasma gondii establishes and maintains a balanced host-pathogen relationship. The experiments have shown changes in the phosphorylizing activity of rat hepatic mitochondria in the dynamics of cold adaptation in animals. Autotransplantation of the adrenal of the rat to the portal circulation: effect of administration of ACTH. Yet, there have been few studies of chronic intracerebroventricular (i.c.v.) melanocortin receptor (MCR) agonist or antagonist infusion. The presence of abnormalities in corticothalamic networks has been suggested to be the functional basis of absence seizure generation. Plasma asymmetric dimethylarginine (ADMA) concentrations are higher in apparently healthy, insulin-resistant (IR) individuals and decrease in response to thiazolidenedione treatment. The experimental sets comprised single as well as double dorsiflexing displacements.

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Genomics, proteomics, metabolomics: what is in a word for multiple sclerosis?. Sp1 activates the transcription of many cellular and viral genes with the GC-box in either the proximal promoter or the enhancer. A comparative study of fluorescence in situ hybridization (FISH) and standard cytogenetic analysis. Based on the assumption that sexual minority individuals are particularly sensitive to the possible rejection of others, the present study examined the occurrence and correlates of social anxiety symptomatology in gay and heterosexual men. A panel of anti-nucleoprotein monoclonal antibodies was used to examine 83 virus isolates from these species. The deformable free surface is obtained as a solution of the coupled transport equations at fixed unit Prandtl number and aspect ratio. Progress in understanding schizophrenia depends on a neurobehavioral approach to resolving the heterogeneity problem.

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