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Anatram (Tramadol)

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Anatram is used to help relieve moderate to moderately severe pain. Anatram is similar to opioid analgesics. It works in the brain to change how your body feels and responds to pain. Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

Other names for this medication:
Armadol, Avdol, Axedol, Cadol, Cemadol, Combitram, Eltram, Haledol, Mobiya, Nomadol, Novadol, Opiran, Painadol, Ramcet, Relidol, Stemadol, Tamody, Tragesic, Tramacon, Tramadex, Tramadol, Tramafen, Tramak, Tramared, Tramazac, Tramdop, Trandol, Transic, Tranzat, Trydol, Ultracon, Unidol, Urogendo, Vintram, Zytram

Similar Products:
Fulvicin, Zyrtec, Noroxin, Ativan, Plavix, Lamictal, Precose, Benicar, Imovane, Myambutol

Also known as: Tramadol


Ultram (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

Ultram is used to treat moderate to severe pain in adults.

The extended-release form of tramadol (Ultram ER) is for around-the-clock treatment of pain. Ultram ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Ultram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Ultram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Ultram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


After this medicine is mixed by your pharmacist, store it at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep container tightly closed to protect from light and moisture. Throw away any unused medicine after 21 days. Keep out of the reach of children.

Side effects

The most common side effects associated with Anatram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Ultram ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Ultram ER should not be given to a child younger than 12 years old. Ultram ER should not be given to anyone younger than 18 years old.

Do not give Ultram ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Ultram ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Ultram ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Ultram ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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The significance of functioning impressions for the stability of full dentures. Mechanical properties of mouse distal lung: in vivo versus in vitro comparison. Eotaxin, eotaxin-2, and eotaxin-3 are important chemoattractants for eosinophils, and these chemokines are expressed during different phases of the allergic reaction. The authors conclude that incidental laparoscopic appendectomy is possible and safe with existing incisions performed in gallbladder surgery. Fourteen pyrimidine-requiring mutants have been classified on the basis of genetic complementation and utilization of biosynthetic intermediates and have been assigned to at least four loci. The first group was no VA supplement as a control, and the second, third, forth groups were daily supplemented with VA 11.43, 42.86 and 142.86 microg RE/kg respectively.

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Polytetrafluoroethylene versus autogenous vein grafts for vascular reconstruction in contaminated wounds. Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate. The molecular weights and the amino acid sequences showed similarity to those of all other known dihydropteroate synthase polypeptides. Combination chemotherapy with cisplatin, vindesine and mitomycin-C for advanced, inoperable non-small-cell lung cancer. Respiratory care centers at two tertiary care referral teaching hospitals in Japan, Hiroshima City Hospital and Okayama Red Cross Hospital. Accommodation request is a complex process that involves cognitive and affective factors for individuals with disabilities. Findings provide preliminary support for the SKT as a valid and reliable tool for assessing stroke knowledge.

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HOM/HOX homeobox genes are present in hydra (Chlorohydra viridissima) and are differentially expressed during regeneration. A dengue 4 (strain H241, PDK35-TD3 FRhL p3) vaccine attenuated by passage in primary dog kidney cells followed by passage and final arcoxia medication vaccine preparation in DBS-FRhL-2 cells was tested in five yellow fever-immune volunteers. The study supplemented with qualitative data through in-depth interview of laboratory service providers. Sensitivity analysis for an improved estimation of respiratory mechanics parameters. The isolation and characterization of plaque-forming arabinose transducing bacteriophage lambda.

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Elevated plasma endotoxin levels correlated with the occurrence of initial leucopenia followed by leucocytosis as well as with clinical symptoms ranging from refusal of food and depression to shock-like symptoms. The proposed model allows generalization of the known analytical models of the viscoelastic periodontal ligament by introduction of instantaneous and relaxed elastic moduli, as well as the fractional parameter. Elimination of clerical work and accelerated flow of information between planning, operation, and evaluation of experiments were found to be the main advantages. The delayed activation of liver xanthine oxidase in rats treated with nicotinamide. All patients had previous US and CT with no clear evidence of irresectability.

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Retrospective ABR study in 10 known kernicteric patients (group I) showed elevation of the hearing threshold and delay of wave I, as well as prolongation of central brainstem transmission, in various degrees, in most cases. These results suggest that inhibition of NF-kappaB activity suppressed alphaCD40-induced liver inflammation at an early phase, resulting in a reduction in cytokine and chemokine production, whereas it sensitized hepatocytes to TNF-alpha-induced apoptosis and exacerbated liver injury at the late phase. The 7.5 kA/m continuous magnetic field has no effect on the studied metabolic indices in the brain whereas the interrupted field (1s impulse duration, 2s interimpulse interval) of the same intensity and exposition lowers the amount of glycogen, glucose, creatine phosphate, the RNA and DNA exposition lowers the amount of glycogen, glucose, creatine phosphate, the RNA and DNA levels, activates the oxidation processes, intensifies their coupling with phosphorylation. Solid pseudopapillary neoplasm of the ovary with metastases to the omentum and regional lymph nodes. Only in absorptive tissue explants from young animals did adsorption of CB5 at 6 degrees C exceed penetration at 37 degrees C. This oscillator should be coupled to the reaction system involving cyclic AMP synthesis and release. The effect of acid pH treatment of circulating immune complexes (CIC) derived from tuberculosis sera was studied on the relative titers of specific antibody (CIC Ab) and mycobacterial antigen (CIC Ag) in the complexes. The contribution of PM1-2.5 to PM2.5 is highest in the summer months, most likely due to enhanced long-range transport. However, the duration of follow-up must balance between what is most relevant for patients, most affected by ICU care, least affected by administrative policies and practically feasible for caregivers.

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This was shown to be a composite effect due to wave form alterations at the hand area electrode and the midfrontal reference site. From the deduced primary structure, leukotriene A4 hydrolase is a 610 amino and protein with a calculated molecular weight of 69,140. Twelve patients after aneurysmal subarachnoid hemorrhage, 40 controls. Female and male patients 30 years or older with idiopathic levaquin dosage sinusitis PD receiving stable doses of levodopa or carbidopa with or without other dopaminergic therapies and who did not experience motor fluctuations were eligible for the study. The effects of intermittent parathyroid hormone (PTH) administration on unloading bone have not been well elucidated at the cellular and molecular levels. Forethought in Youth with Attention Deficit/Hyperactivity Disorder: An fMRI Study of Sex-Specific Differences. The effects of T-2 toxin on bacterial infection and leukocyte function and structure were examined in vivo and in vitro. Synthesis of polyspongouridylic acids from uridylic acids and phenylpolyphosphate esters.

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Incidence and Outcomes of Inferior Vena Cava Filter Thrombus during Catheter-directed Thrombolysis for Proximal Deep Venous Thrombosis. When organoids cocultured with human foreskin fibroblasts were grafted within chambers, structural organisation of the epithelium was supported. Agreement and discrepancy in the evaluation of normal and diabetic oral glucose tolerance test. Bovine liver dihydropyrimidine amidohydrolase: pH dependencies of the steady-state kinetic and proton relaxation rate properties of the Mn(II)-containing enzyme. Identification of a 140-kDa activation antigen as a target structure for a series of human cloned natural killer cell lines. BudR and light treatment of T cells proliferating in the SMLR abolished their subsequent primary and secondary proliferative response to antigen but had little effect on their response to allogeneic Ia. aeruginosa condensins specialize in the establishment of the sessile and planktonic states of the bacterium.

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A novel 19G EUS-guided liver biopsy needle provides superior histologic yield compared with 18G percutaneous needles and existing 19G FNA and core needles. Intestinal adaptation to zinc absorption following massive small bowel resection and colon interposition in rhesus monkeys. Volume augmentation of the anophthalmic orbit with cross-linked collagen (Zyplast). Fungal spores and pollen grains were identified when possible at the level of species. CTL activity was measured in cell-mediated lympholysis (CML) against target cells from all Kb mutants and B6-H-2b. These observations have been incorporated into a model which, on evaluation, predicts all of the observed potential changes during the action of 5-HT.

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