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Amodipin (Amlodipine)

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Amodipin is an inexpensive drug used to treat chest pain and high blood pressure (hypertension). It is more popular than comparable drugs. It is available in generic and brand versions. Amodipin is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Amlodipine, Amlotens, Amodipin, Amtas, Amtim, Amvasc, Antacal, Calbloc, Cardivask, Ciplavasc, Coroval, Dafor, Edidipin, Imped, Kaprin, Lodimax, Lopiten, Myostin, Nolmoten, Ozlodip, Pelmec, Perten, Presdeten, Presovasc, Sidopin, Suplar, Tenox, Tensigal, Vazotal, Zundic

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Also known as: Amlodipine


Norvasc (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Norvasc is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Norvasc is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.


Take Norvasc exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You may take Norvasc with or without food. Take the medicine at the same time each day.

Your blood pressure will need to be checked often.

Your chest pain may become worse when you first start taking Norvasc or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.

If you are being treated for high blood pressure, keep using Norvasc even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your hypertension or heart condition may be treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or stop taking any of your medications without your doctor's advice. This is especially important if you also take nitroglycerin.

Norvasc is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Norvasc dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include rapid heartbeats, redness or warmth in your arms or legs, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Amodipin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Norvasc if you are allergic to amlodipine.

To make sure Norvasc is safe for you, tell your doctor if you have ever had:

liver disease; or a heart valve problem called aortic stenosis.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Norvasc will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breastfeeding.

Norvasc is not approved for use by anyone younger than 6 years old.

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A qualitative study using semistructured interviews with 56 voluntary village birth attendants. These results suggest that 5-HT has an important part in locomotor activity of eels. The clastogenic potential in vitro of pyrrolizidine alkaloids employing hepatocyte metabolism. Altered sexual development in male rats after oestrogen administration during the neonatal period. We studied 76 patients with essential hypertension (48 males and 28 females) and 65 healthy controls (33 males and 32 females). We found a replication-defective proviral sequence consisting of putative Gag and Env proteins flanked by long terminal repeats. Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria.

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The differential diagnosis between anorchia (5 patients) and bilateral cryptorchidism (12 patients) was possible with evaluation of FSH and Testosterone plasma levels before and after hormonic stimulation. Effect of repeated treatment with antidepressant drugs or electroconvulsive shock (ECS) on the increase in food intake induced by clonidine injected into the paraventricular nucleus. Agents which can prevent chemiluminescence and cytochrome c reduction, such as superoxide dismutase (SOD), reduced NK-mediated cytolysis and agents which increased chemiluminescence, such as interferon, also increased NK-mediated cytolysis. For metastasis studies, tumors were resected, followed by systemic administration of ASOs and the presence of metastatic nodules in lungs and liver was assessed. A variant of the margo cranialis scapulae: dystopia spina scapulae. Capacity of T4 DNA to serve as template for purified Escerichia coli RNA polymerase.

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An increase in uterine contractility in response to as little as 1.0 MUG PGF2alpha could be observed in all patients during both the early and late portions of the menstrual cycle, but at the time of ovulation a marked decrease in sensitivity was noted. The effect of sympathetic and parasympathetic stimulation on the vulnerable period threshold and the protective zone was studied in chloralose-anaesthetised dogs. doctors) in many cases collaborate in order to provide care to patients in a more proficient way. Two patients went on to have their symptoms controlled on topiramate (50-300 mg daily). Studies on mechanisms of diarrhea induced by fusarenon-X, a trichothecene mycotoxin from Fusarium species: fusarenon-X-induced diarrhea is not mediated by cyclic nucleotides.

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Each TLR displays a difference in the expression pattern, intracellular localization, and signaling pathway, resulting in the distinct immune responses. Induction of the major stress response in chick embryo fibroblasts, which follows infection at 38.5 degrees C with the herpes simplex virus mutant tsK, was investigated. We examined 49 PD patients and 49 age- and sex-matched healthy controls by spectral domain optical coherence tomography (SD-OCT) with a circular scan centred at the optic disc. This methyltransferase activity is directed specifically to arginine 17 of histone H3. The bar-properties, in particular glucsylation of deoxyribonucleic acid, in crosses of bacteriophages T2 and T4. Activation of the capacity for sodium-induced pinocytosis in Amoeba proteus. Only reversible thrombopenias and an increase in the alpha 2-globulins fraction were observed in the interferon and in the control group, resp.

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Ophthalmology Unit, Santa Maria Nuova Hospital, Reggio Emilia, Italy. Prostatic cancer cell cultures possessed intracellular immunofluorescent antigens specific for human cytomegalovirus (CMV) but produced no infectious virus particles. One hundred normal American Blacks (B) were studied by sequential QFQ and RFA banding techniques in order to estimate the type and frequency of heteromorphisms. Resection of only the cyst is adequate in completely isolated cases. In both groups antisaccades had lower peak velocities than prosaccades. Normal values have been obtained for 2-hydroxyisovaleric acid, the sum of 2-hydroxyisocaproic acid and 2-hydroxy-3-methylvaleric acid, 2-methyl-3-hydroxybutyric acid, 3-hydroxyisovaleric acid and 2-ethyl-3-hydroxypropionic acid. The second approach to CT urography combines axial CT with thin-section excretory phase CT. Agency theory and options theory suggest that for-profit managed care plans, in the presence of debt, will engage in less hedging activity than will other managed care plans. Commonly used partition coefficients can be easily related to the model and adsolubilization isotherms may be reproduced by the developed equation. The density of DBH-positive axonal boutons within the reticular nucleus neuropil is greater than that found in the relay nuclei of the dorsal thalamus (with the exception of the anterior group nuclei).

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The wealth of clinical trials and post-marketing information for sumatriptan may be useful in guiding prescribing decisions for members of this class of drugs. The data suggest that, overall, air medical personnel use these agents safely and effectively. Diagnosis is confirmed by the presence of malignant cells in the cerebrospinal fluid or by clinical and neuroradiographic pattern compatible with leptomeningeal metastasis. This is the first reported case of this rare condition occurring following bone marrow transplantation. This paper reports the effect of vagal denervation on gastric emptying and also examines the site and mode of action of receptors in the proximal small bowel. Surface characterization revealed that the constructed copolymer brush layers exhibited an uniform super-hydrophilic nature and different surface potentials. In the first step, each video is decomposed into supervoxels by the unsupervised video segmentation. Physico-chemical properties of terrylytin modified by a copolymer based on vinylpyrrolidone. The antisense oligonucleotides also inhibit the degree of granulation by mast cells derived from culture.

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Function of lymphocyte subpopulations in chronic lymphocytic leukemia. Variation of river system with ecological restoration might influence the abundance and distribution of immature mosquitoes. In contrast only a slight inhibition in IL-1 alpha induced u-PA production was seen when gamma-IFN was added to the cells 8 hours after IL-1 alpha. PMN phagocytic uptake of 14C labeled Staphylococcus aureus was depressed in BDL (p less than 0.05). The quantities of AFP messenger RNA in these 3 cases were relatively high among 8 cases with AFP-positive status. Cells are then collected by centrifugation and then seeded onto collagen surfaces.

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Surfactant-enhanced release of carbaryl and ethion from two long-term contaminated soils. Evaluation of the TOPKAT system for predicting the carcinogenicity of chemicals. Comparison of objective and subjective measurements of cough frequency in patients with seasonal allergic rhinitis. The effects of sudden alterations in load on human intercostal muscles during voluntary activation. Interactions among Drosophila larvae before and during collision. For the second strain, which was methicillin resistant but cephalosporin susceptible, vegetations were positive for 14 of 15 untreated controls, 4 of 20 receiving cefazolin, 5 of 22 receiving cefamandole, none of 20 receiving vancomycin, and none of 20 receiving LY146032. The behavioral effects of cocaine (0.03-3.0 mg/kg i.v.) were determined in squirrel monkeys (Saimiri sciureus) trained to respond under a fixed-interval 300-sec schedule of stimulus termination.

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Multiple skin abscesses associated with fever required operative debridement. Cerebral trauma and traumatic infection of the central nervous system. All 10 cases appeared to have solitary masses on contrast enhanced computed tomography (CT). Pacemaker implantation in familial congenital A-V block complicated by Adams-Stokes attacks. This layer was visible before bone formation occurred, and was collagen free. The authors summarize the special characteristics of the acute appendicit and the pregnancy. Recessive ataxia with ocular apraxia: review of 22 Portuguese patients. Then a dual triangular pattern deployment based on our novel data fusion strategy is proposed, which can utilize collaborative data fusion more efficiently. Immunotherapy (recombinant interleukin 2), hormone therapy (medroxyprogesterone acetate) and antioxidant agents as combined maintenance treatment of responders to previous chemotherapy. The iatrogenic (physician-induced) and nurisgenic (nurse-induced) factors related to such functional disabilities are described.

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The in situ absorption characteristics of nuclei stained for DNA-aldehyde molecules with either an aqueous solution of azure B or with TCA-azure B-SO2 show peak-absorption at 600 nm in both cases. The effects of short-term oral iron therapy on developmental deficits in iron-deficient anemic infants. Separation of short stumps of the shoulder from the cicatricial adhesion to the skin of the chest. These changes do not explain the beneficial effect of rhIL-11 on the lowered contractility in inflamed rabbits although a change in balance of neuropeptides may influence gastro-intestinal inflammation. Sodium starch glycolate and the cation-exchange resin merit careful consideration by formulators using calcium phosphate dibasic dihydrate or similar direct compression matrixes. These findings indicate that these omega-3 fatty acids have a larger prophylactic potential than traditional approaches.

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1) In non-treated rats, epinephrine, isoproterenol and phenylephrine, which were injected intravenously, clearly increased plasma uric acid and allantoin, and norepinephrine had only a slight effect. Decreased collagen gene expression and absence of fibrosis in thyroid hormone-induced myocardial hypertrophy. Nitration of 2-methyl-4-hydroxypyridine and 2-methyl-4-ethoxypyridine. This was tested by incubating end sections of 11-d cartilage, which have little alkaline phosphatase activity, and center sections, which have significantly alkaline phosphatase activity, with both BtcAMP and MIX. Birth weight is associated with sarcopenia in men and women, independently of adult height and weight.

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This work establishes a Dps-mediated link between light tolerance, H2O2 detoxification, and iron homeostasis, and provides further evidence on the non-redundant role of multiple Dps proteins in this multicellular cyanobacterium. In conclusion, chronic inhibition of nitric oxide synthesis in vivo produces a long-lasting reduction in the capacity of coronary arteries to generate new capillaries in vitro. Abdominal distension in very low birth weight, small for gestational age infants. Magnitude and distribution of occlusal forces on oral implants supporting fixed prostheses: an in vivo study. The presence of two or more pH-dependent substates of porin could explain the variability in pore diameter measured by others and suggests a more dynamic role for porin in the cell. Our results indicate the large (alpha) subunits of DRw2 and DRw7 antigens are nearly identical, while their beta subunits show many differences. The radical neck dissection has proven itself to be an essential tool in the management of cancer in the head and neck. Airway management for penetrating neck injuries: the Miami experience.

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The boxes were equal in weight but unequal in size and were attached to an instrumented grip handle which measured the employed grip force, load force, position and their corresponding time derivatives. The authors had under observation 21 patients with diastematomyelia--a rare congenital disease marked by the formation of a bony spicule in the vertebral canal, which splits the spinal cord and its meninges. Comparison of AIA and NIOSH methods on asbestos fibre measurements in the workplace. We used 24-hour urine samples that were collected within the framework of the second screening for the PREVEND Study, a prospective cohort study on albuminuria in the city of Groningen, The Netherlands. Interaction of Escherichia coli hemolysin with biological membranes. Right atrial diverticulum presenting as Wolff-Parkinson-White syndrome. Using patch-clamp recordings, artificial dynamic conductance injection, pharmacological analysis and computational modeling, we show that spike time irregularity is generated by a nonlinear dynamical interaction of voltage-dependent sodium and fast-inactivating potassium channels just below spike threshold, amplifying channel noise. Action potentials of the right ventricular working myocardium of newborn and adult rabbits under paired stimulation conditions. The transmission pattern of smallpox in a West African school population.

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Nuclear families (127 probands and their 130 siblings) for the linkage analysis were ascertained through asthmatic children. The proceedings of the 25th annual meeting of the Japanese Society albendazole cost uk of Child Neurology. Dynamics of adsorption and desorption of proteins at an air/water interface. Posterior reversible encephalopathy syndrome (PRES) has well-established links with several drugs. There was, however, an associated significant increase (p less than 0.01) in the slopes of the subsequent histamine dose-response curves. Our latest studies have revealed that the BBB transporters play important physiological roles in maintaining the brain milieu. In this report, we aim to understand the prevalence and occurrences of such neurovascular manifestations in four heritable connective tissue disorders: Marfan syndrome, Ehlers-Danlos syndrome, Neurofibromatosis Type 1, and Loeys-Dietz syndrome. Actions of novel bombesin receptor antagonists on pancreatic secretion in rats.

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Proceedings: Experiments to demonstrate the relationship between 133-Xenon clearance and renal blood flow. The mechanisms by which cells acquire the capacity to invade interstitial connective tissues during malignancy are as yet motrin 800 mg uses uncertain. Axial stretch modifies contractility of porcine coronary arteries by a protein kinase C-dependent mechanism. Effect of the medium on the functional and structural properties of serum albumins. The effect of guar on the absorption of the calcium isotope 45Ca was measured in six normal subjects. Lupus myocarditis is likely more common than recognized clinically due to non-specific symptoms and lack of reliable non-invasive diagnostic tests. Most cases of ALU intoxication occur during hemodialysis due to treatment of aluminum-containing drugs. We conclude, the R2 measure of the Poisson regression quantifies the predictability of event rates, but it is not adequate to quantify the predictability of the outcome of individual observations. Mechanism of action of injection therapy for bleeding peptic ulcer. Use of enzyme proteolysis for the immunochemical measurement of insulin.

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N-terminal addition of glycine to amino acid and peptide esters activated by the cobalt(3) ion. Radiation sensitizing agents in clinical radiation and chemotherapy. LC regularly expressed macrophage inflammatory proteins, MIP-1 alpha and MIP-2, and interleukin 1 beta (IL-1 beta). Seasonal prophylactic treatment with pirenzepine to prevent duodenal ulcer recurrence. Glutaraldehyde, the biological fixative of choice in the cytochemical localization of the phosphatases, was investigated for its effects on Pseudomonas aeruginosa alkaline phosphatase. Scanning electron microscopy of the cecal mucosa in Eimeria-tenella-infected and uninfected chickens.

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Primary care practices in community settings can implement significant and lasting changes in their practice environment that will improve their performance of preventive activities. Antigenic difference between intracellular and membrane antigens induced by herpesvirus of turkeys. Virus type in patients with initial episodes was best predicted by initial and mean type 2 antibody levels and in patients with recurrent disease by the ratio of type 1 to type 2 antibody by radioimmune assay. Immunohistochemistry with antibodies directed against keratins 1, 4, 5, 12, and 14 as well as loricrin, filaggrin, and involucrin were performed in corn1/corn1 and wild type, A.By/SnJ strain, mice at 4 weeks of age. The results indicate no notable medical, nutritional, or toxic problems in the wild Komodo dragon population.

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The patients were divided into drug responders group and non-responders group according to the reducing rate of Y-BOCS score. The pressure flow test is useful in the diagnosis or exclusion of obstruction in the upper urinary tract. post operative treatment ribavirin dosing chart and shock therapy well dosed infusions are needed. The results of histological analysis and serological study were compatible with CS. Aspiration breast cytology yielded insufficient material for diagnosis.

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Nuclear staining qualities, and cell morphology depart from normal when epithelial cells are infected by herpes virus hominis and herpes varicella-zoster (1). The finding of tenascin and of the three isoforms of cFn in glomerular synechiae with actively proliferating epithelium suggests that certain epithelial cells might partake in the synthesis of these molecules. The features of this peptidergic system, its topographic distribution to form intrinsic circuits within the posterior hypothalamic area and probably connections with the pituitary, suggest implications in brain neuromodulatory activities and hypophyseal regulation for this peptide. Using cDNAs specific to the inserts of avian sarcoma virus genomes, we examined the existence and the transcription of cellular nucleotide sequences related to the three new onc genes of avian sarcoma virus (fps, yes and ros) in various cells. For both the stimulating and challenge infections, there were no significant differences in the number of flukes recovered from rats that had been splenectomised as compared to those receiving the sham operation. We report here the first crystallographic study of the SARS spike HR-N/HR-C complex. Daily exercise-induced cardioprotection is associated with changes in calcium regulatory proteins in hypertensive rats. Ascending and cerebellar non-serotonergic projections from the nucleus raphe magnus of the rat. We use the double and multiplicative binomial distributions to model over- and under-dispersed sex allocation and show how to calculate Bayes factors for comparing these alternative models to the null hypothesis of binomial lamisil oral tablet 250 mg information sex allocation.

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Proceedings: Clinical evaluation of arteriosclerosis--comparison of findings by ophthalmoscopy, plethysmography and other tests. rhG-CSF infusion suppressed the liver metastasis and prolonged the overall survival, thus suggesting the hypothesis that use of rhG-CSF in some patients with NHL might control the disease through stimulating both production and functional activation of neutrophils. GDP binding activity was localized solely to the mitochondria in both control and cold-adapted brown adipose tissue. Hazards included failure to provide recommended venting, neglected maintenance, or use in small areas without natural ventilation. Physicians respond to patients with high stress and low support by offering more medical services. Our data suggest that enhanceosome assembly is critical for developmentally appropriate activation of Ealpha in vivo, and that transcription factors, Sp1 and pCREB, may play unique roles in this process. However, LRPs obtained during imagination trials had smaller amplitudes. Saline administered to Group 2 rats produced little or no response but subsequent nicotine resulted in responses similar to those produced by Group 1 animals. The faster rate of synthesis in dystrophic muscle was partially due to an increase in the concentration of cellular RNA. Sixty minutes after starting a pentagastrin infusion class of medication plavix (0.15 micrograms/kg/h) either placebo or proglumide was infused intravenously.

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Can standardised clinical examination of athletes with acute groin injuries predict the presence and location of MRI findings?. Phosphopeptides from aqueous cheese extracts were completely retained on iminodiacetic acid (IDA) Sepharose equilibrated with FeCl3 and subsequently eluted with ammonium dihydrogen phosphate. CHW is a large and diverse hospital system that developed a systematic planning process to define, prioritize, and assess the current status of those functionalities needed by caregivers to assist them in providing optimal care. This regulation of sOB-R appears to be independent of leptin, but may have an impact on leptin action. In addition, its evolution to an atypical fibroxanthoma-like morphology is of interest, because some view atypical fibroxanthomas as bizarre variants of squamous cell carcinoma. Establishment and characterization of human leukemia cell lines (J6-1, J6-2 and J6-3). In balanced order the subjects were exposed to a condition in which they viewed the stimuli for 15 sec and a condition in which they could escape the stimulus. Neither normal splenic L-I B-cells nor L-I thioglycolate-induced peritoneal macrophages were defective at presenting native ovalbumin, to six and eight different I-As-restricted T-T hybrids, respectively.

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Since the presence of the retinal vasculature precludes such a simple quantitative analysis of local oxygen consumption within the inner retina, our understanding of the oxygen needs of the inner retinal components is much less complete. The phenotype of diabetes in MIDD appears to be independent of HLA-DQ phenotype and degree of heteroplasmy in leucocyte and oral mucosa DNA indicating that other, as yet unknown, factors modulate clinical expression of the 3243 mutation. We reviewed all the trough concentrations of protease inhibitors and nonnucleoside reverse transcriptase inhibitors that were performed for therapeutic failure, suspected drug toxicity, or routine purposes. Sodium excretion and the blood levels of aldosterone, renin, atrial natriuretic peptide (ANP), and insulin were investigated in 9 women with obesity of alimentary-constitutional type during hunger therapy and resumed nutrition. Hypothetically, the breaks should comprise two essentially different kinds: primary breaks that are actively involved in the malignant development, and secondary breaks, coincidental to this process. Epicardial electrocardiogram (ECG) was also recorded to analyze the incidence of ventricular tachycardia (VT) and ventricular fibrillation (VF). Genotoxicity of textile dye effluent on fish (Cyprinus carpio) measured using the comet assay.

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