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Amixide (Amitriptyline)
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Amixide

Amixide is not FDA-approved to treat insomnia (trouble falling or staying asleep), but one of the side effects of the medication is sleepiness, especially when you first start taking it. Because of this, you may want to take it in the evening or before bedtime when you first start taking it.

Other names for this medication:
Amicon, Amicure, Amitar, Amitone, Amitrac, Amitrip, Amitrix, Amitrol, Amixide, Amizep, Amoten, Amrea, Amsha, Amypres, Arpidox, Cotrip, Eptanol, Libotryp, Libral, Librodep, Limbitrol, Maxitrip, Mitryp, Nextrip, Raitrip, Relidep, Tridep, Trixide, Tryline, Tryptomec, Typlin

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Also known as: Amitriptyline

Description

Elavil (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Elavil is a prescription medicine used to treat symptoms of depression.

Dosage

Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Elavil dosage information

Overdose

If you overdose Amixide and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amixide overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amixide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Elavil if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Elavil if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Elavil is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Elavil is not approved for use by anyone younger than 12 years old.

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The expressed major histocompatibility complex (Mhc) class II DRB genes of 50 unrelated deer were examined by reverse transcription polymerase chain reaction, cloning, and sequencing of DRB exon 2. These data confirm the mutagenic effect of CDDP in rats demonstrated for mice bone marrow by micronuclei assay, for murine ovary cells and mice spermatocytes. The fibroblast-like synovial cell in rheumatoid arthritis: a key player in inflammation and joint destruction. Attempts to visualize the cerebello-thalamo-cortical path in the rat were made with different approaches. To monitor the stem cell migration into the bone defect following an injection of the labeled mesenchymal stem cells (MSCs) by the enhanced green fluorescent protein (EGFP) technology and to provide insights into an application of MSCs for the fracture healing. The fact that these disturbances do not always lead to an advanced blockage of A-V conduction is discussed as being reminiscent of the prospective and retrospective studies in the similar case of bi-fascicle block. We assume that cardiac complications after butane inhalations may partly be secondary to intense coronary artery spasm on the basis of the clinical and laboratory findings. Introduction of the living human body in freshman gross anatomy. The etiology of CPP may arise from multiple sites in the pelvis including the bladder, pelvic peritoneum, and vulva.

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The observed rise in lexA mRNA rules out any role for protease activity or resulting fragments of lexA protein in de-repression of RNA. Only sera from cats exposed to the FIPV type-II strains DF-2 or 79-1146 that were exhibiting signs of FIP recognized the fusion protein. Clustering of pathogenic mutations implies differential structural sensitivity along the keratin molecule, and implications for filament function require a new look at culture assay systems, plus a reassessment of structural defects in epithelial and other tissues. We used thermal coronary angiography (TCA) for intraoperative graft patency control in 370 patients undergoing routine coronary artery bypass graft surgery to determine whether consequent intraoperative bypass graft control may result in improved patency rates. Cerebral amyloid angiopathy: a significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly. The study was carried out in the surgical intensive care unit (SICU) of an teaching hospital. This kinase activity phosphorylated two proteins of 62 and 72 kDa that coimmunoprecipitate with Nef in in vitro kinase assays. However, there were no significant differences in various measurements of resource utilization, including days in hospital, hospital charges, and need for post-hospital rehabilitation. Gingko biloba extract diminishes stress-induced memory deficits in rats. Separation of oppositely charged proteins or subunits by disc electrophoresis.

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Some factors potentiating platelet development promote the proliferation of megakaryocyte progenitor cells, while others result in their maturation. A lambda cDNA library prepared from polyadenylated RNA isolated from Daudi cells was differentially screened to isolate cDNAs that recognize mRNA whose levels are reduced following interferon (IFN) treatment. Because of physician preference, patient adherence, or toxicity, some patients did not reach that goal. Experimental data are discussed in relation to current models of speech production. The appearance of bacteria resistant to antibiotics makes ceftriaxone or ciprofloxacine the empirical treatment of choice. The observation of more frequent leukemias in immune deficiencies of the non-HLA-restricted cytotoxic cell system and the participation of this system in the anti-leukemic effect of allogeneic bone marrow transplantation in acute leukemia indicate that these cells might play a role in the immune surveillance against leukemia. A series of ten patients underwent laryngectomy and creation of a phonatory neoglottis as outlined by Staffieri. Application of the quartz lamp in the roentgenologic screening apparatus. The analysis is based on 10,947 breastfed singleton infants born between July 2003 and June 2004 who survived to day 2 and whose mothers were visited in the neonatal period. The diazotized sulfamethazine (SMZ) is accumulated on a mercury electrode by electrochemical adsorption and is then stripped cathodically.

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A line-bisection test of visual attention was not sensitive to the effects. First observations on enzymatic zonulolysis of Barraquer in cataract extraction. ASO staff experience tension between a historical grassroots organizational culture characterized by responsiveness and relevance and a more recent culture of professionalization. Autoradiographic localization of dopamine D2-like receptors in the rat adrenal gland. We conclude that there has been a striking increase in the prevalence of malignancy among resected indeterminate SPLs over the past 14 years in our institution. The trifurcated SMAS flap: three-part segmentation of the conventional flap for improved results in the midface, cheek, and neck. Combined membranous obstruction and saccular aneurysm of the inferior vena cava. The second CF mutation was delta F508 and 1677delTA in the two families respectively, both reportedly associated with severe phenotypes. Angiogenesis and lung cancer: prognostic and therapeutic implications.

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Uptake and oxidative utilization of glucose, fructose and galactose by rat mast cells. From the result, rare pulmonary sequestration in the left upper lung field was diagnosed because patterns with inflow of an abnormal artery from descending aorta into the left upper lung field and perfusion of it into the upper pulmonary vein were observed. This staining pattern appeared gradually and became more intense during development. The hypercalcaemia of vitamin D intoxication is mediated by increased bone resorption and bisphosphonates have a role in its management. The formation of liposomes with low polydispersity index by application of ultrasounds was investigated considering methodology specifications such as sonication time and sonication power. Telomerase activity is suppressed in normal somatic tissues but is activated in most cancer cells. The steps in the development of this technique are outlined and the surgical technique and preliminary results described. Localization of endoglin, a transforming growth factor-beta binding protein, and of CD44 and integrins in placenta during the first trimester of pregnancy.

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Lead exposure has previously been associated with intellectual impairment in children in a number of international studies. Our results provide evidence that composition within richness levels had often larger effects on the stability of aboveground ecosystem processes in the face of fire disturbance than species richness per se. The relationship of in vivo thrombogenicity to the nature of the starting plasma. It is estimated that by 2009, Hispanics will have the highest birthrates for any minority group in the United States. Cement-free cup and cemented shaft--concept of a hybrid solution and results of a 3-to-6-year clinical experience. Brain impact injury was reproduced in SD rat with a free falling impacting device. SPG27 was recently mapped to chromosome 10 in a single family with autosomal recessive hereditary spastic paraplegia (AR-HSP) and a pure phenotype.

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nov., a novel yellow pigment-producing bacterial species, isolated from rhizospheric soil in Cordoba, Argentina. Furthermore, apoptotic 50-kb DNA fragmentation was observed in the HeLa cells, which was well correlated with occurrence of phosphorylation of Chk2. Both the alpha and beta chains of high-affinity interleukin 2 receptors are located in intracellular vesicles when their ligand is endocytosed. New data on epicardial activation in the dog: comparison with the results obtained in man. The results indicate that many patients in general practice will find it useful to read their medical record. We present and discuss an approach to treat BCS complicated by acute PVT. Within the arcuate nucleus, the distribution of SSTR1 and SSTR2 messenger RNA-expressing cells was comparable to that of neurons previously found to selectively bind somatostatin-14 within this area. This might have an influence on the functional activity of the antibodies. Accidental perforation into the bladder in an attempted pneumoperitoneum. Immunoglobulin levels at different ages in the healthy child population.

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To test the biological activity of the R385H mutant, we transiently expressed wild type, R385H, and R389P Gs alpha cDNAs in COS-1 cells. Review of a PCI database of 9,088 consecutive PCIs from July 1997 to December 2002 identified 812 PCIs in patients with a history of prior stroke and 8,044 PCIs without prior stroke. Toluene diisocyanate induction of airway hyperresponsiveness at the threshold limit value (10 ppb) in rabbits. Butyrate and propionate: important components of toxic dental plaque extracts. This article highlights applications of risk-based surveillance systems in the veterinary field including food safety. However, functional outcome after ischemia depends critically on adaptations of the postischemic brain. It is evident that cryptogenic bronchiolitis represents the result of a disordered inflammatory response in the small airways of the lung. In addition, family background regarding skin alterations or other arsenic-related symptoms was explored, so that individual health conditions could be assessed. Potential genotoxic, mutagenic and antimutagenic effects of coffee: a review. In 3 patients from whom Ad8 or Ad37 was isolated, there were discrepancies between serological results of the neutralization test or the haemagglutination inhibition test, and viral isolation.

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Role of mucosal microcirculation in gastric lesions induced by lateral hypothalamic lesions in rats. Such a system also predicts that minimum and maximum perceivable spatial displacement thresholds should scale with visual field eccentricity in a manner consistent with our results. Depression of thalamic metabolism by lorazepam is associated with sleepiness. These data were compared with the data of patients of 20 to 30 years of age in a statistically standardised manner. X-rays of 205 horses having navicular disease and having been reexamined up to six times are evaluated. Quantitative 31P NMR detection of oxygen-centered and carbon-centered radical species. Quantitative study of the uptake of IgA by isolated rat hepatocytes. Self-image resilience and dissonance: the role of affirmational resources. Contribution of cycloergometrics to the identification of ischemic damage in pre-excitation syndromes. Secondary sites of hybridisation observed at 5p1.5, 1q4.2-4.4, 1p2.1-2.2, and 20p1.3 most likely are attributable to partial sequence homologies with related NFI genes.

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Dual inhibitory and stimulatory activities in serum from SLE patients and lupus mice that regulate the proliferation of an IL-2-dependent T cell line. All the cell lines expressed c-kit ligand gene constitutively, and this expression was not increased by lectins. A review of literature of this complication and a discussion about its physiopathological mechanism and prevention is presented. The two groups did not differ with respect to their demographic data, extracorporeal circulation, aortic cross-clamping time, or number of distal anastomosis. Sex sustiva mg -related differences in reproductive steroid levels further confound efforts to define the specific role of the sex of the individual in stress axis responsivity. All metabolic variables except triglyceride did not correlate significantly with intra-abdominal fat accumulation. Construction of 110 cosmid markers and a 4.5-Mb YAC contig on human chromosome 8p12-q11. Diagnostic accuracy studies in nonimmune individuals with suspected malaria were included if they compared rapid tests with expert microscopic examination or polymerase chain reaction tests. Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Perceived incidence was not affected by urban size or university affiliation of practice.

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Brazil nuts obtained from various commercial process operations located in Peru were similarly evaluated. Determination of specific activity of beta-galactosidase using resorufin-beta-galactopyranoside as substrate in homogenates of whole embryos heterozygous for the human c-myc/lac Z transgene demonstrates significantly elevated beta-galactosidase activity over control embryos in day 11 and day 14 embryos. burgdorferi in the collective of patients with the human immunodeficiency virus infection together with the possibility of presenting similar clinical manifestations has led to extreme prudence in the diagnosis of infection by B albenza . The lines are spaced apart by the actual programmed values (lower rate, AV, VA intervals) of the pacemaker in question. FDG-PET in early infancy: simplified quantification methods to measure cerebral glucose utilization. When oocytes were treated with Triton X-100, they failed to respond to 1-MeAde and DTT. Degradation of a Plasticizer, di-n-Butylphthalate by Delftia sp. Limits of quantification after SPE of 100 mL of water are between 3 and 80 ng/L, which are adequate for most aqueous samples. This response was significantly attenuated by scavengers of NO or inhibitors of NO synthase.

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The relatively infrequent adoption of a long-term, annual, screening pattern in the face of certain knowledge of personal high risk gives cause for concern about the effectiveness of any intervention program requiring recognition of personal high risk for effectiveness. We elicited respiratory sensations by having participants breathe through circuits that differed in their resistance to air flow. On the prophylaxis of postoperative thromboembolic complications with magnesium. Erythrocyte catechol methyltransferase activity in endogenous depressive syndromes. The other ethanol-treated group that had free access only to solid chow and water containing ethanol lost weight during the exposure period.

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