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Amiodarona (Amiodarone)
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Amiodarona

Amiodarona causes antiarrhythmic and antianginal effects. Antiarrhythmic effect is stipulated by diminishing of K+ ions transportation though cell membranes of myocites and diminishing of sinus node automaticity. Amiodarona automatically blocks a- and b-adrenoreceptors. Relief of paroxysmal tachycardia attacks, relief of other heart attacks and treatment of ventricular fibrillation. Amiodarona is for use only in life-threatening situations and should be used strictly according to recommendations of your doctor.

Other names for this medication:
Amidrone, Amiobal, Amiocar, Amiodacore, Amiodar, Amiodaron, Amiodarone, Amiodaronum, Amiodura, Amiogamma, Amiohexal, Amiokordin, Amiotach, Amirone, Ancaron, Ancoron, Angoron, Angoten, Aratac, Atlansil, Braxan, Cardilor, Cardiron, Corbionax, Cordalin, Cordan, Cornaron, Coronal, Coronax, Daritmin, Daronal, Diarona, Escodaron, Eudarona, Eurythmic, Keritmon, Miodrone, Mioritmin, Nodis, Opacorden, Pacerone, Pacet, Rhythmiodarone, Rithmik, Ritmocardyl, Rivodaron, Rivodarone, Sedacoron, Tiaryt, Trangorex

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Also known as: Amiodarone

Description

Amiodarone is used to treat life-threatening heart rhythm problems called ventricular arrhythmias. This medicine is used in patients who have already been treated with other medicines that did not work well.

Amiodarone belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep your heart rhythm normal.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain amiodarone. It may not be specific to Cordarone. Please read with care.

You will receive your first dose of this medicine in the hospital. Your doctor will watch you closely after you take this medicine to make sure you do not have any serious side effects.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Do not miss any doses. It may also take 1 to 3 weeks before your body responds to this medicine.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food, but take it the same way each time.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For ventricular arrhythmias: Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Your doctor may adjust your dose as needed and tolerated. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Amiodarona and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiodarona are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Immune suppression (cyclosporine A at 20 or 60 micrograms/g body wt) had no effect on either acute-phase reactions or local tumor growth. Technetium-99m labelled human serum albumin for ventriculography: a comparative evaluation of six labelling kits. The synthesis and characterisation of some 3,6,20-trioxygenated pregnane derivatives. The latter one is lateralized in chick and suggested to be involved in visually evoked social behavior, like recognition of novelty, predator, and conspecific animals. Distension was not significantly correlated with age but wide variation between individuals may limit the value of measurement of this change in size as a diagnostic test. With regard to self-sufficiency, supply and demand for plasma-derived products can only be reconciled if there is a free exchange of source materials and products with European harmonization of products. In this study we evaluated thyroid function in CF in order to verify these data and to evaluate if the modifications were related to serum levels of markers of inflammation and growth factors that we have previously shown to be altered in CF. The assay had a sensitivity of 0.14 ng/ml plasma when 100 microliters plasma was assayed.

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Chemical and physicochemical properties of the H antigen (flagellin) isolated from Salmonella abortus ovis. Research on the sensitivity of the total tonsillar flora to the most common antibiotics. Desmoid tumours of the extremities and trunk: a review of the literature. Fluorescence microscopy indicated that a significant reduction of GFP fluorescence was only observed in the cells that were treated with polyamide C. Determining N7-alkylguanine adducts by immunochemical methods and HPLC with electrochemical detection: applications in animal studies and in monitoring human exposure to alkylating agents. A table has been developed for use by physicians that lists the name of the antibiotic, the drug concentration in the cord and maternal plasma at delivery and the type of transfer involved.

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With the conditions adopted for the purpose of the study, Pt was found to exert an advantageous effect on the adsorption of n-heptane. A clarification of terms and concepts for developmental psychopathology. PMN elastase, complement C3, or coeruloplasmin, and on the other hand, by secretion markers such as alpha-glucosidase, PSA and phosphatase. Bosentan prevents endothelin-induced fibroblast proliferation and extracellular matrix deposition and contraction, and reduces cardiac, hepatic, pulmonary and renal fibrosis in different disease models characterized by the activation of the endothelin system. Hyperbaric oxygen may be an effective, but rarely practical prophylactic measure. Hierarchical cluster showed that distinct groups of genes uniformly changed their expression values in response to the stress. Post-icteric cirrhosis with diabetes and hypocalcemia in a patient with Rendu-Osler disease. Emission-to-noise ratio and response reproducibility were more similar between groups. Symptom improvement will also depend on whether the condition is acute, subacute or chronic heart failure. Apart from stat3, another cytoplasmic protein was tyrosine phosphorylated and subsequently translocated to the nucleus in response to IL-2.

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Staphylococcus aureus-induced antigen-specific immunosuppression. Intracerebral bleeding in a patient with neurosarcoidosis while on corticosteroid therapy. Recombinant antigens that have been cloned from Taenia solium and Taenia ovis have been shown to be highly effective when used as vaccines against cysticercosis in the intermediate hosts. UCDS is a computerized system of data collection and case finding developed by the Health Care Financing Administration (HCFA) to standardize the Peer Review Organization screening process for potential utilization and quality problems. Loading sequence rather than elastic recoil seems to play the predominant role in the enhanced load sensitivity of left ventricular relaxation in heart failure. Interrelationship of pyrrole and globin metabolism in beta-thalassaemia. Occasional urine samples and blood samples withdrawn at the time of urinary collection were examined.

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Biopsies of photodamaged skin from the extensor aspect of the forearm and skin from the buttocks, which had been protected from the sun, were performed on 26 healthy subjects. This retrospective study examined the influence of a hospital palliative care team on the activity of a local hospice home care team over a four-year period from May 1989 to April 1993 in East Leeds. The increase in tissue perfusion at constant blood pressure and pulse rate must be interpreted as an expression of vasodilation. No correlation was found with any growth factor or cytokine analyzed. The results here demonstrate that a synthetic IgNAR variable domain library based on a single framework scaffold can be used as a route to generate antigen binders quickly, easily and without the need of immunization. Neural network analysis of the P300 event-related potential in multiple sclerosis. In the rectosigmoid region of every type of isolated HSCR, we observed transmural nerve fibers forming meshworks in the CML with TUJ1 and S100 antibodies. In several studies, uPA and PAI-1 proved to be of prognostic relevance as shown for different types of cancer (e.g. One case of a thoracic spinal cord injury without bony abnormalities in an adult is reported, and the pertinent literature is reviewed. In this work, we describe the hsp90-binding domain of FKBP59-HBI.

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Surgical resection of patients with multidrug-resistant tuberculosis combined with chemotherapy provides a favorable outcome. Vacuum metal deposition: visualisation of gold agglomerates using TEM imaging. A model for the assessment of the animal disease risks associated with the importation of animals and animal products. Islets were incubated with 3,3 and 16.6 mM glucose and insulin and nifedipine er osmotic 30 mg tablet ACTH-like products (ACTH-LP) were measured by radioimmunoassay. Short-wavelength-sensitive (SWS) resolution acuity has been reported to be limited by the density of the responding ganglion cells for people without appreciable age-related lenticular change.

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Population immunity to ribonucleoproteid antigen had no influence on the epidemic process in influenza A. The serum IgG antibody response to the foreign gene product, influenza H1, was suppressed by the passively administered anti-influenza antibody in a dose-dependent manner. when patients treated with a drug differ in their underlying risk of adverse outcome from patients given alternate treatments, independent of the effect detrol generic name of the drug). A study of the pathogenesis of Helicobacter pylori negative chronic duodenal ulceration. Court involvement in right -to-die cases: judicial inquiry in New York.

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Whereas 18/20 classic MBs showed very low levels of CXCR4 mRNA, high amounts were expressed in 17/18 desmoplastic and 6/7 extensively nodular MBs. The correlation between LH and insulin sensitivity suggests a complementary action in PCOS. Disturbance of one of these systems may induce a pathological condition. When expressed as isolated, affinity-purified protein constructs, NBF2 of SUR1 exhibits increased in vitro ATP hydrolysis compared to NBF2 of SUR2A. Successful surgical treatment of a pseudoaneurysm after composite graft replacement of the aortic valve and ascending aorta: report of two cases. The median radiation dose was 60 (40-62) Gy in the evaluable patients. Tetradecylthioacetic acid (a 3-thia fatty acid) decreases triacylglycerol secretion in CaCo-2 cells.

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System analysis and planning for public health care in the City of New York. The aberrant localization of SP and TH may represent an altered repair process associated with resolution of the infarction and may be related to abnormal respiratory control or sudden death. Of the 15 sheaths 10 have eroded into the urethra and 4 sheaths remain in situ. We studied the activity of these mutants using the yeast two-hybrid system and an in vitro kinase assay. In the current study, the role of platelet-activating factor (PAF) in combination with tumor necrosis factor (TNF)-alpha in corneal myofibroblast apoptosis was explored. The predictive value of assessment at 5 years for later performance and behaviour at 11 years is also discussed.

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Calcium was mainly localized in dark pinealocytes characterized by many ultrastructural signs of degeneration. The outside-in signaling may also be activated by bradykinin itself. Influence of peritoneal dialysis on the progression of chronic renal failure. White blood cell fragments in platelet concentrates prepared by the platelet-rich plasma or buffy-coat methods. These experiments showed that mutation of a -67 to -85 element, which contained a putative Sp1 binding site, or mutation of a -44 to -53 GAS element resulted in a marked reduction of Jak3 promoter activity. Significant odds ratio (OR) results were used as a statistical tool to survey the putative link between AD and ARMD. Perhaps the most unique aspect of these studies is the fact that, with rare exception, both acute and chronic ethanol exposure have been found to slow growth and to lower tissue polyamine (putrescine) content. Studies using these chitinases as EBR markers revealed that the virulent Pseudomonas syringae pv. All patients were surgical candidates or were considered for invasive EEG monitoring and had undergone an extensive presurgical evaluation at a tertiary epilepsy center. The number of colocalized foci and their overlapping area increased in the presence of DNA damage produced by genotoxic treatments either during S phase or in exponentially growing cells.

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Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in biaxin drug classification patients with solid, malignant tumors. In the present study, using immuno-electron microscopy, we examined the location of this hamster oviductin-1 (Hm Ov-1) in hamster oviductal oocytes and early embryos up to the blastocyst stage. The treatment includes non-ideal solution behaviour as measured by osmotic pressure of highly concentrated macromolecular solutions. Hip and knee proprioception in elite, amateur, and novice tennis players. Similar to Tat, we showed that Rad51 interacts with C/EBPbeta and augments its interaction with the DNA motif spanning nucleotides -120 to -94 of the LTR. An analytic method is presented for assessing the marginal impact of incremental changes in rural Emergency Medical Services (EMS) on cardiac mortality, morbidity, EMS system process and performance, and health care system utilization. A significant body of evidence supports the concept of predicting drug efficacy and toxicity by SNP genotyping.

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The model was necessary to facilitate statistical testing between examinations. When RNA encoding Xenopus mos (mosxe) was injected into oocytes, Raf-1 and MAP kinase mobility shifts were observed after several hours. Glutamic oxalacetic and glutamic pyruvic transaminase activities of normal and leukemic leukocytes. Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. In contrast with the central nervous system, the peripheral nerves are usually considered radioresistant. Multi-site study of incidence of pressure ulcers and the relationship between risk level, demographic characteristics, diagnoses, and prescription of preventive interventions. Anergic B cells constitutively present self antigen: enhanced immunoglobulin receptor-mediated presentation of antigenic determinants by B cells is hierarchical. Middle ear susceptibility to Pseudomonas infection during acute otitis media. Thus MAP kinase activation is an immediate early response to heat shock, and its increased activity is calcitriol drug classification maintained throughout heat shock treatment.

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