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Ambien (Zolpidem)

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Zolpidem and Ambien 10 mg are the best sleeping tablets for insomnia patients. Zolpidem is a sedative, also called a hypnotic. It affects chemicals in your brain that may become unbalanced and cause sleep problems (insomnia). Zolpidem is used to treat insomnia. The immediate-release forms of zolpidem are Ambien, Intermezzo, Edluar, and Zolpimist, which are used to help you fall asleep. The extended-release form of zolpidem is Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep. Ambien, Edluar, and Zolpimist are used to help you fall asleep when you first go to bed. Intermezzo, is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping.

Other names for this medication:
Ambiz, Ambulax, Azold, Dactive, Getrest, Isodem, Lopitas, Lypin, Restem, Sobrium, Zanlop, Zedem, Zleep, Zodem, Zolfresh, Zolit, Zolnex, Zolpiapt, Zolpidem, Zolpimist, Zolpirest, Zolpistar, Zolsoma, Zoltar, Zolway, Zomnia, Zopid

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Clomid, Alprostadil, Trileptal, Combivent, Keflex, Flagyl

Also known as: Zolpidem


Zolpidem is used to treat insomnia (trouble sleeping). It belongs to the group of medicines called central nervous system (CNS) depressants, which slows down the nervous system. Zolpidem will help you get to sleep faster and sleep throughout the night. In most cases, sleep medicines should only be used for short periods of time, such as 1 or 2 days, and for no longer than 1 or 2 weeks.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain zolpidem. It may not be specific to Ambien CR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take zolpidem just before going to bed, when you are ready to go to sleep or when you are having trouble falling asleep. This medicine works very quickly to put you to sleep.

Swallow the extended-release tablet whole. Do not divide, crush, or chew it.

Do not take this medicine when your schedule does not permit you to get a full night's sleep (7 to 8 hours). If you must wake up before this, you may continue to feel drowsy and may experience memory problems, because the effects of the medicine have not had time to wear off.

Take this medicine on an empty stomach.

Do not take this medicine if you have drank alcohol the same evening or just before bedtime.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of insomnia: For oral dosage form (extended-release tablets): Adults—6.25 milligrams (mg) (for women) or 6.25 or 12.5 mg (for men) once a day at bedtime. Your doctor may increase your dose as needed. However, do not take more than 12.5 mg per day. Take only 1 dose a night as needed. Older adults—6.25 mg once a day at bedtime. Children—Use is not recommended. For oral dosage form (tablets): Adults—5 milligrams (mg) for women and 5 or 10 mg for men once a day at bedtime. Your doctor may increase your dose as needed. However, do not take more than 10 mg per day. Take only 1 dose a night as needed. Older adults—5 mg once a day at bedtime. Children—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of zolpidem can be fatal, especially when it is taken together with other medications that can cause drowsiness.

Overdose symptoms may include sleepiness, confusion, shallow breathing, feeling light-headed, fainting, or coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Ambien are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Use of zolpidem is not recommended in children. Safety and efficacy have not been established.

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The balloon was inflated with a diluted suspension for visualization of the balloon and widening of the stenosis. A simple method for the treatmen of stenosis of the upper respiratory tract. Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex. The nitrogen hyperfine coupling constant of DTBN arising from those probes occupying the vesicles is used to study the hydration of the vesicle surface. The nuclear membrane as a barrier to the free diffusion of proteins. The atmospheric concentration of arsenic was different in different sampling stations was dependent to the traffic density. Two fragments of FKBP42 from Arabidopsis thaliana covering differing lengths of the molecule have been expressed, purified and crystallized.

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Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery. Discrimination analysis as a tool for classifying the value of biochemical and immunological tests in lung cancer. The subject nevertheless continued to press the key whenever he emitted a thumb twitch, and he reported that he still heard the tone. A semistructured interview also included the administration of an instrument that contained the formulation of reasons. This study set out to identify and describe a group of patients who did not receive continuity of care from the general practitioner with whom they were personally registered. In amoebae of the eukaryotic microorganism Dictyostelium discoideum, calmodulin is greatly enriched on membranes of the contractile vacuole complex, an osmoregulatory organelle. We show that these two peptides are identical and that they are formed from basement membrane collagen IV. Old studies and those from developing countries suggest that pregnancy considerably increases the risk of stroke. Biomechanical and neuromuscular characteristics of the involved limb of the posterior cruciate ligament-deficient subjects were compared to their uninvolved limb and to 10 matched control subjects performing gait and drop-landing tasks. Fetal wastage is high, apparently because of spontaneous abortion during the first and second trimesters.

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The patients initially feel intensive pain in one shoulder, which typically is followed by motorical weekness of the proximal upper arm and the shoulder. Subunit immunogens composed of well-defined T- and B-cell epitopes might represent a valuable approach to design vaccines. Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry. Preference for costly fluoroquinolones by casual workers and daily wage earners in developing countries. A synthetic peptide modeled on the c-Src carboxyl terminus, which contains phosphotyrosine at position 527, binds recombinant SH2 and the SH2-domain of c-Src which lacks phosphotyrosine 527. Normal values of semen collected from Spanish goats by two methods.

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Preoperative plasma- and thrombocytapheresis in patients with ischemic heart disease. Immunological factors involved in the endotoxin detoxifying capacity (E.D.C.) of rat plasma. Second, after the 1988 calendar year the cesarean section rate of every obstetrician was circulated annually to each attending physician. Eradication of these vessels might lead to a more durable therapeutic effect. Possible mechanisms of crosstalk between ABA and auxin signaling are discussed. Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination.

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Nitrogen-fixers--pseudomonads and other aerobic bacteria--from Rhodesian soils. Detection of Charcot-Leyden crystals by fluorescence microscopy of Papanicolaou-stained smears of sputum, bronchoalveolar lavage fluid, and bronchial secretions. Thus, compounds bearing in the 7-position a methyl or a methoxy group or devoid of a substituent in this position, and bearing an ethyl, an isopropyl, or a cyclobutylamino group in the 3-position were found to be potent and selective inhibitors of insulin release from rat pancreatic B-cells (i.e. The RVS167 gene product displays significant homology with the Rvs161 protein and contains a SH3 domain at the C-terminal end. This proves that the intranuclear formations are structural modifications of the Y chromosome itself. Thus, with fluoridation the variation in caries between high and low deprivation groups was significantly reduced but not eliminated, leaving the level significantly lower in the least deprived group, to the continuing disadvantage of that deprived group.

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In the primary cultures, the maximal yield of PLT-cells was observed early (about day 7) and decreased thereafter, while the maximal specificity was obtained considerably later (about day 14). In this study, we analyzed hepatic coagulant, fibrinolytic, and anticoagulant functions between Banna Minipig Inbreds (BMIs) and humans to evaluate such hepatic compatibility. These disorders, inherited as an autosomal dominant trait, have frequently been described in various ethnic groups, but have rarely been reported in Italy. Technetium-99m (V) DMSA scintigraphy may be superior to Tc-99m HMDP scintigraphy for distinguishing benign and malignant chondrogenic tumors, and could also be useful for diagnosing the malignant transformation of chondrogenic tumors. However, it is still a matter of debate which part of the immune system is implicated in its pathogenesis as a reaction to the still unknown antigen. Some epitopes were more accessible to enzymatic digestion than other epitopes. Thrombin, a pluripotential effector enzyme with prothrombotic, proinflammatory, and mitogenic properties, plays a pivotal role in the pathobiology and clinical expression of atherothrombotic coronary artery disease. Effect of succinylation on some physico-chemical and functional properties of casein. DHA potentiated the NMDA-induced response but reduced the non-NMDA (kainate-induced) response in a concentration-dependent manner at a holding potential of -60 mV under voltage-clamp conditions. Guinea pig ear stratum corneum was removed to increasing depths by 1, 3, 6 or 9 strippings with adhesive tape.

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Currently, however, the clinical usefulness of PSA concentrations detected in the ultrasensitive range after radical prostatectomy is unknown. Tissue binding sites involved in quinidine-cardiac glycoside interactions. The results indicate that RP patients can be classified into two categories according to the effects of rhodopsin loss on rod sensitivity. We recently encountered a father and son with these manifestations. A biophysical investigation of recombinant hemoglobins with aromatic B10 mutations in the distal heme pockets.

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Thus ACE inhibitor, despite only partial control of systemic blood pressure, effectively prevented proteinuria and glomerular injury. The recommendations for treatment at TJUH of victims of gunshot or stab wounds with a resultant neurologic deficit are as follows. Patterns of vertebral ossification and pelvic abnormalities in paralysis: a study of 200 patients. No convincing evidence of transdifferentiation of huEPCs into cardiomyocytes was obtained. Finally a number of issues related to threshold scores, research design and the need to view pressure sores as a clinical problem rather than a nursing problem are discussed. Neurologic and other disorders in relatives of pediatric patients with CNS tumors.

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Long-term results of continuous ambulatory peritoneal dialysis: the first hundred patients. Four patients had palliative radiotherapy and were dead of disease within 6 months. This outbreak illustrates the danger of connections between potable and non-potable water systems, and emphasises the importance of complying with existing water byelaws. A series of four trials was conducted to compare the influence of several design variables on the strength of bones from coop and floor-reared broilers. Pseudomonas fluorescens: production of pyoverdine in human blood at 4 degrees C and cytotoxic effect of the pigment. We examined the effects of intrarenal infusion of EXP3174, a non-peptide angiotensin II receptor antagonist, in order to evaluate the physiological role of endogenous angiotensin II in regulating renal hemodynamics and urine formation and to assess the possibility of a tubular site(s) of action of endogenous angiotensin II in anesthetized dogs. The guanosine/thymidine-containing oligonucleotides (GTOs) which demonstrated anti-FMLV activity in acute infection assays were synthesized with natural phosphodiester (PD) linkages (backbones). Degradability and sediment sorption of an alcohol polyglycol ether surfactant putatively useful for the control of red swamp crayfish in rice fields. Collagen alpha 1(IV), laminin B1 and B2 genes were expressed throughout the mesenchyme and epithelium.

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Furthermore, the purification of active prolylendopeptidase from the extract of recombinant bacterial cells is described. No significant leftward laterality was detected with the slice-based technique, suggesting that a significant portion of superior temporal gyrus tissue is omitted with this approach. Interpretations of the transition probabilities as measures of disease prevalence are discussed. Effect of prolonged dietary treatment on atherosclerosis in the mature fowl. There are indications of endogenous control for some physiological processes (eg, the metabolic responses to a given intensity of exercise) that seem to mediate more favorable effects of exercise on body composition in the winter. Oncogenic activation of the macrophage colony stimulating factor (M-CSF) receptor (c-Fms) requires mutation or truncation of the carboxyl terminus and specific amino acid substitutions in or near the fourth immunoglobulin (Ig)-like loop in the extracellular domain. Three case reports are presented in which successful localization of the offending neoplasm was accomplished by using whole-body Tc 99m sestamibi scanning. mansoni and other non-human trematodes occurred in all 4 areas, despite some ecological differences and the effects of earlier treatment campaigns in 1 of the study areas.

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Rechallenge of the animals 6 months after recovery with the same viral inoculum failed to produce abnormal liver function tests indicating the presence of protective immunity during this period. Anti-CD3 treatment facilitates engraftment of full H-2-disparate donor bone marrow cells and subsequent skin allograft tolerance. FK506 neurotoxicity in patients with liver transplantation commonly results in transient neurological manifestations. The kinetics are consistent with a sequential folding and assembly mechanism involving two increasingly nativelike monomeric intermediates en route to the native S100A11 dimer. The inclination of the femorotibial helical axis of rotation did not change with knee flexion or after surgery. Engineering the structural stability and functional properties of the GI domain into the intrinsically unfolded GII domain of the yeast linker histone Hho1p. An 11-year-old boy presented with medulloblastoma occurring in the cerebellar vermis. Decreased compliance is an infrequent finding after radical prostatectomy. However, Bcl-2 is further enhanced following prolactin stimulation for 4 h and this enhancement is desogestrel and ethinyl estradiol brand name uk blocked by DFMO.

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The occipital artery is a vessel of satisfactory size and is potentially a good vascular source for a thin galeal free flap. We observed that MAA markedly inhibited CO2 production from glucose, acetate and citrate at concentrations as low as 0.01 mmol/L. Spine and spinal cord injuries, with particular reference to the cervical region. Reported side-effects include nausea, vomiting, diarrhoea, constipation, and headache. The CB2R is expressed mainly in cells of the immune system, suggesting that the CB2R is involved in immunoregulatory events. Molecularly imprinted polymers as tools for the screening of felodipine from dihydropyridine calcium antagonists by pressurized capillary cozaar 50 mg losartan potassium electrochromatography. From E16 to E18 the retinal ganglion cells showed increasing reactivity and the pattern of reactivity followed the centro-peripheral pattern of retinal development. These effects were concomitant with immediate renal and mesenteric vasoconstriction.

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We attempted to demonstrate the expression of cytomegalovirus (CMV) particles in the serum of an acute lymphocytic leukaemia patient with CMV pneumonia. Bivalirudin is a safe and effective anticoagulant for patients undergoing a wide range of cardiac surgical procedures with cardiopulmonary bypass. When embryo serum or plasma was mixed with vitreous humor or IGF-1, agents that induce lens fiber cell formation, cell elongation was prevented. Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention. Pigs are used for hemodynamic studies and often in therapeutical studies if species-specificity of the drug tested is not important, in cases where a large animal is necessary. TB preventive or therapeutic measures directed towards this group should be implemented in Brazil.

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The changes on the surface of the cells infected with the virus of Newcastle disease (NDV) occurred in the early hours after the infection and before the appearance of a cytopathic effect. Too many physicians: physician-assisted suicide after Glucksberg/Quill. Present indications are that the model will be applicable not only to the different sectors of the population, e.g., women and children, but also to many other villages throughout the country. Vaccines cannot be expected to have a beneficial effect on recurrent genital, ocular, and facial herpes. A diagnosis prilosec 30 mg of cancer places huge psychological and physical demands on individuals.

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This stage having been surmounted with excellent results, work continued with the experiment in emergency surgery and surgery of choice, on the basis of the criterion of greater safety as a complement of the traditional high dehiscence risk suture technique. In fact such effect can be easy excluded by analizing the temporal relationship between the ventriculograms registered during His bundle stimulation and the atriograms. In hepatocellular carcinoma, the altered methylation patterns accompanying malignant transformation override the age-dependent increase in gene methylation. These results indicate that newly synthesised collagen is a prerequisite for expression of the endothelial cell phenotype for tube formation and that prevention of collagenous protein biosynthesis inhibits tube formation and angiogenesis in vivo. Induction of labor using prostaglandin E2 (PGE2) vaginal gel in triacetin base. Assessing structural changes in the brain to evaluate neurotoxicological effects of NMDA receptor antagonists. Differentiation of mononuclear cytotrophoblasts into syncytiotrophoblasts in vitro increase the IFN nexium dosage oral production.

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Primary defect in UVB-induced systemic immunomodulation does not relate to immature or functionally impaired APCs in regional lymph nodes. The combined levels of dynamic gene expression throughout the presomitic mesoderm enable cells to acquire positional information, thus giving them a notion of time. Inhibition of receptor binding by high-affinity RNA ligands to vascular endothelial growth factor. In the seven asymptomatic patients with a subnormal cortisol response to ITT, the diagnosis of adrenal insufficiency was confirmed in one by LDSST, in none by SST, and in five by CRH tests. Differential effects of propofol and enflurane on contractions dependent on calcium derived from the sarcoplasmic reticulum of guinea pig isolated papillary muscles. Position of The American Dietetic Association: environmental issues. The records on eighty-four shoulders that had undergone open repair of the subscapularis tendon were reviewed.

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Gastric exfoliative cytology: the importance of a negative examination. These data suggest that RTIDPCR may be useful in evaluating gene expression by cells processed as cytologic specimens. Recently, we have observed that arginine facilitates elution of antibodies during Protein-A chromatography and solubilizes insoluble proteins from inclusion bodies, which both can be ascribed to weakening of protein-protein interactions. The use of virtual microscopy for proficiency testing in gynecologic cytopathology: a feasibility study using ScanScope. Questions were designed to gather information regarding factors that may have influenced career path choices. This finding indicates that the inability of this mutant to stimulate adenylyl cyclase is caused by the reduced capacity for vasopressin binding and that the R181C mutation is responsible for NDI in this family. Is the computer-based patient record an analog or a model of the patient?. A novel substrate has been developed that further facilitates the measurement of chitotriosidase in plasma samples.

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A series of cloning vectors, designated YCpIF, was constructed to facilitate the conditional synthesis of epitope-tagged, truncated and chimeric proteins in Saccharomyces cerevisiae. The Sequence Ontology: a tool for the unification of genome annotations. The Sarfarazi accommodative intraocular lens, currently in clinical studies, is a single continuous silicon accommodative lens with dual optics and three haptics that mimic the action of the natural lens by using the contraction and relaxation of ciliary muscles. The authors reviewed the literature for side effects of five first-line antituberculous medications (isoniazid, rifampin, pyrazinamide, ethambutol and streptomycin). However, at pH 6.4 and 37 degrees C, lysozyme is monomeric and actin filament cross-linking is observed. Anesthesia was continued uneventfully with propofol infusion while all facilities were available to detect and treat malignant hyperthermia. Voltage-dependent gap junctional conductance in hepatopancreatic cells of Procambarus clarkii. Other phospholipases, such as phospholipase C and phospholipase A2, could not prevent cell death. Recently, BBIs have become a hot topic because of their potential applications. The preservation of mammalian ova and embryos at positive near-zero temperatures.

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The main outcome measures were the mean sensitivity (MS) change in the central moduretic 25/2 5 mg bula 15-degree visual field and the MS change in the 15- to 30-degree visual field. Portal hypertension in children in the light of our observations. In addition, there was a possible association between the age and ethnicity of patients with insomnia/sleep difficulties and the prescribing of expensive medications for sleep difficulties. Thus, after 5 d there was an increase in GAL- and CCK-IR fibers in the internal layer. Characterization of carbon-supported AuPt nanoparticles for electrocatalytic methanol oxidation reaction. Recently, serum cystatin C was proposed as a new endogenous marker of GFR and in our study its diagnostic accuracy was compared with that of other markers of GFR.

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Our methods are based on the recent result which demonstrated that the set of images of a convex Lambertian object obtained under a wide variety of lighting conditions can be approximated accurately by a low-dimensional linear subspace. Results of neonatal hearing screening with transitory evoked otoacoustic emissions. In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropriate treatment. When patients with known sickle cell disease present with symptoms of abdominal pain, (1) the character of the symptoms, (2) precipitating events, (3) white blood cell count, (4) bilirubin, and (5) fever should be compared with those characteristics in previous crises. The 44-kDa and 42-kDa forms corresponded to extracellular signal-regulated kinase (ERK)-1 and ERK-2, respectively. Except for one patient who developed transient quadriparesis that resolved spontaneously within 2 days, no bleeding complications or neurologic deficits attributable to the procedure were noted. One of the 9-mer peptides, AAGIGILTV, was most effective in sensitizing the T2 cells for TIL lysis.

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Peptides containing fewer glutamic acids had lower affinity to the crystal. Clinico-radiologic contribution to the study of primary neoplasms of the ureter. Pharyngeal bot flies (Oestridae) from sympatric wild cervids in southern Spain. Clinical and laboratory findings simulating infectious-toxic states in mental hospital patients treated with tranquilizers before admission. Semen volume, the pre-freeze and post-thaw motile sperm count, motion parameters and the percentage decrease in semen variables did not differ significantly among the groups. Since these pathways are implicated in cell proliferation and cell death, these pathways may play a role in determining the overall sensitivity of a cell to TGF-beta1 induced cell growth inhibition. Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike.

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Sensitivity analyses were performed over wide ranges of probability and cost what type of medication is bactrim estimates. Total hysterectomy for benign pathologies: why is laparoscopy of value?. then per os has proved to be an efficient treatment for acute myelitis. This is an exploratory study of the abuse-especially sexual-of female adolescents in a conservative and traditional Bedouin-Arab community in southern Israel. Effects of adrenergic blocking agents on human fallopian tube motility in vitro. The anatomicoclinical, epidemiological and therapeutic aspects of 76 cases. Gross examination of the injection sites with increasing time showed that the polymer gels were progressively replaced by cartilage. In tissues other than the liver, HMG-CoA reductase activity was unaffected in responding rats. These data were fitted with the difference of the integrals of two Gaussians. A novel method utilizing high-performance liquid chromatography (HPLC) with evaporative light scattering detection (ELSD) and electrospray ionisation mass spectrometry (ESI-MS) was developed for the analysis of soyasaponins, a divers group of triterpenic compounds with one or two sugar side chains, occurring in soy.

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