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Alpuric (Allopurinol)
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Alpuric

Alpuric is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.

Other names for this medication:
Algoric, Allgoric, Alopur, Aloric, Aluric, Axanthine, Biorinol, Ciploric, Estinol, Gudloric, Kayloric, Lodiric, Mecnol, Purinol, Purolic, Satric, Seloric, Swiloric, Ureka, Uridip, Urigon, Urxoall, Zanupirol, Zeric, Zyloric, Zyrinol, Zytol

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Also known as: Allopurinol

Description

Allopurinol is used to prevent or lower high uric acid levels in the blood. It is also used to prevent or lower excess uric acid levels caused by cancer medicines or in patients with kidney stones. A high uric acid level can cause gout or gouty arthritis (joint pain and inflammation). Allopurinol is a xanthine oxidase inhibitor that works by decreasing the uric acid produced by the body.

This medicine is available only with your doctor's prescription.

Dosage

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

You may take this medicine after meals to avoid stomach upset.

Take this medicine with plenty of liquids to help prevent kidney stones. Check with your doctor about the amount of liquid you should drink each day. You should also increase your fiber intake.

You may need to lessen your intake of animal protein, sodium, refined sugars, or foods rich in oxalate and calcium, especially if you have kidney stones that keep coming back.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For gout: Adults—At first, 100 to 300 milligrams (mg) per day, taken once a day or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children—Use and dose must be determined by your doctor. For high uric acid levels caused by cancer medicines: Adults and children 11 years of age and older—600 to 800 milligrams (mg) per day, taken in divided doses for 2 to 3 days. Children 6 to 10 years of age—300 mg per day, taken once a day for 2 to 3 days. Children younger than 6 years of age—150 mg per day, taken once a day for 2 to 3 days. For kidney stones: Adults—200 to 300 milligrams (mg) per day, taken once a day or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 800 mg per day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Alpuric and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from light and moisture. Do not store in the bathroom. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alpuric are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of allopurinol in children with high uric acid levels caused by cancer.

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Reduction of cocaine self-administration and D3 receptor-mediated behavior by two novel dopamine D3 receptor-selective partial agonists, OS-3-106 and WW-III-55. During learning, the middle-sized ring was sometimes followed by the outcome, whereas a larger ring was never followed by the outcome. In the dilated cisternal space, gold particles were freely and evenly distributed, without preferential binding to the luminal surface of the ER membranes. Biomicroscopic examination showed lice and nits anchored to the eyelashes in three cases. Flow study of surgical coronary artery fistula as an alternative to sequential bypass. Regulation of synaptic timing in the olfactory bulb by an A-type potassium current. Enzymatic characterization of zona pellucida hardening in human eggs and embryos. Recent evidence suggests that visual working memory (VWM) load reduces performance accuracy on a concurrent visual recognition task, particularly for objects presented in the left hemifield.

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F mediates male reproductive toxicity in mice down-regulating 63 genes involved in diverse biological processes - apoptosis, cell cycle, cell signaling, chemotaxis, electron transport, glycolysis, oxidative stress, sperm capacitation and spermatogenesis. Establishing the central zone of scaphoid 3D CT images provided a baseline for discussion of central placement of a scaphoid screw. The cartilage was modeled as linear elastic material, and in addition to its elastic modulus, interaction effects of soft tissue material properties were added compared to previous research. Our findings suggest that an impaired DDR and DNA repair may contribute to the pathogenesis of neurodegenerative diseases linked to FUS mutations. These data suggest that while recognition memory for familiar items may fade over time, recognition of novel items, conscious recollection in particular may benefit from a period of consolidation. Abdominal ultrasonography showed that the involved kidneys were small and hydronephrotic. AF ablation is associated with a higher incidence of tamponade compared to other procedures that require transseptal access. The antibody bound with equal affinity in solid phase radioimmunoassays to fibrinogens isolated from both normal patients and patients with von Willebrand disease.

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Horizontal gene transfer in osmotrophs: playing with public goods. Predictors of Distant Metastasis after Radical Surgery Followed by Postoperative Radiotherapy with or without Chemotherapy for Oropharyngeal Cancer. Acute wound fluids and normal human serum did not contain enzymes capable of degrading fibronectin. The objective here was to investigate which environmental forces are driving elevated abundances of V. These results suggest that low doses of the selective kappa 1 agonists U-50,488H and U-69,593 are endowed with anxiolytic properties in rodents and that the kappa opioid system may be involved in the behavioral response to anxiety. Effect of Optison on pulmonary artery systolic pressure and pulmonary vascular resistance.

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