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Alpant (Pantoprazole)

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Alpant is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn. Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alpant is to be taken empty stomach.

Other names for this medication:
Athzol, Azpan, Gastrorid, Healcer, Hyzole, Impan, Metop, Odipan, Pandiff, Pandostal, Panfast, Panpure, Pansaul, Pantact, Pantadom, Pantakind, Pantaron, Pantest, Pantocar, Panton, Pantosis, Pantozil, Panzest, Pentavel, Pentorex, Proplus, Protocent, Recozol, Ropenta, Shamzole, Sunpen, Syntac, Tupent, Vipan, Wonon, Xylopan

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Also known as: Pantoprazole


Protonix (pantoprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Protonix is used to treat erosive esophagitis (damage to the esophagus from stomach acid caused by gastroesophageal reflux disease, or GERD) in adults and children who are at least 5 years old. Pantoprazole is usually given for up to 8 weeks at a time while your esophagus heals.

Protonix is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid.


Take Protonix exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Use the lowest dose for the shortest amount of time needed to treat your condition.

Protonix is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.

Protonix tablets are taken by mouth, with or without food. The oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break a Protonix tablet. Swallow the tablet whole.

The oral granules should be sprinkled on 1 teaspoon of applesauce or apple juice and given either by mouth or through a nasogastric (NG) tube.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

Call your doctor if your symptoms do not improve or if they get worse while you are using this medicine.

Pantoprazole can cause false results with certain medical tests. Tell the doctor or laboratory staff that you are using this medicine.

Pantoprazole may also affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use this medicine.

Store this medicine at room temperature away from moisture, heat, and light.

Detailed Protonix dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alpant are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pantoprazole injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.

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The result of treatment of sixty-four patients with infected ununited fractures of long bone by debridement of soft tissue and bone and open suction-irrigation drainage, followed by rigid stabilization of the non-union and cancellous bone-grafting when indicated, was bone union in sixty cases, even in the presence of infection. The subcellular localization of SSeCKS in endothelial cells correlated with some pinocytic pits and phago-lysosomes, although a diffuse distribution of SSeCKS in the cytoplasm was also visible. The plasma concentrations of antithrombin III, protein C and protein S in capillary and venous blood samples obtained simultaneously from 30 neonates were compared in order to determine the suitability of using capillary blood for estimation of these proteins with anticoagulant action. However, despite this high prevalence and burden of disease, current treatment regimens necessitate long durations of therapy, are often poorly tolerated and have suboptimal rates of sustained virologic response. Effects of decaborane on liver glycogen content of rats at ground level and at altitude. Though we cannot preclude the existence of a transcriptional regulatory mechanism, our results point to the participation of changes in the stability of histone mRNAs as a regulatory mechanism of their levels during the cell cycle in Trypanosoma.

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A case of acute respiratory distress syndrome induced by fulminant influenza A (H3 N2) pneumonia. In spite of hundreds of harmless retrobulbar applications of anesthetics and drugs, a certain risk still exists. This pattern of metabolic development may be important for understanding the development of overt circadian rhythms. A simple radiochemical assay is described for measuring the activity of rat heart mitochondrial acetyl-CoA synthase (EC and octanoyl-CoA synthase (EC using labelled acetate and octanoate. The biological value of selenium in bovine milk for the rat and chick. Transmission electron microscopy micrographs of healed epidermis in treatment group showed melanocyte with normal morphology. Uncompensated readers showed deficits in orthographic and especially phonological coding and awareness and were slower on rapid naming.

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Tissue distribution and metabolic fate of 3-ethoxycarbonyl-5,5-diphenylhydantoin (P-6127) and 5,5-diphenylhydantoin in rats. There was also no short term change in plasma alpha-MSH concentrations in patients after receiving their first treatment with PUVA. The porcine neurotubule and its basic subunit were found to be modified in vitro by iodination of amino acids (principally tyrosine) using lactoperoxidase. Effects of a reduction in external sodium ion concentration on actions of some smooth muscle stimulants. Enhancement of thymine dimer formation in solutions of DNA occurred upon addition of ethylene glycol. Enterococcus faecalis pheromone-responsive protein PrgX: genetic separation of positive autoregulatory functions from those involved in negative regulation of conjugative plasmid transfer. xenopi are summarized in a review of the literature and criteria for the diagnosis of atypical cutaneous mycobacterioses are proposed. LAMC2-positive leukoplakia had an approximately 11-fold increased risk of malignancy compared with LAMC2-negative leukoplakia. The MS Functional Composite (MSFC), a recently developed outcome measure for MS clinical trials measuring three dimensions (ambulation/leg function, arm/hand function, and cognition), was applied to 134 patients with MS to study the concurrent validity, using MRI measurements as a biological disease marker. Kappa-opioid receptor subtype was purified from digitonin solubilized preparation of frog brain membranes by hydrophobic and Sepharose 6B chromatography.

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Up until now, no one has been able to give consumers meaningful data about health care and health benefit alternatives. Comparison in changes in blood coagulation tests during use of oral contraceptives. We also describe a series of complementation experiments in which transport or postpolymerizational modification functions for one K antigen are used to complement mutations in the corresponding regions of a different K-antigen gene cluster. Three of five patients with refractory myeloma were successfully palliated using a simple and relatively nontoxic regimen consisting of weekly cyclophosphamide in combination with alternate-day oral prednisone. Persistence of viable tumor cells after radiation and chemotherapy for stage IIIB non-small cell lung cancer: an early marker of treatment failure. The serum concentrations of osteocalcin (bone Gla protein) were followed by continuous blood sampling for 24 h in 9 healthy young women before and during treatment with oestrogen/progestogen combinations for oral contraception. Following training, the VO2max was increased (p less than .01) from 4.32 to 4.68 1.min-1. Hemoglobin Deaconess a new deletion mutant: beta131 (H9) glutamine deleted.

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The aim of this study was to examine the relationship between the serum levels of IL-1b, IL-6 and TNF-a as well as the concentrations of soluble TNF receptor I (sTNF-RI) and C-reactive protein (CRP) in patients with squamous cell carcinoma of oral cavity. The specificity of procaine as a limbic epileptic focus activator was investigated in rats kindled in the amygdala. Pulmonary nodules are a less common manifestation of aspergillosis in immunocompetent patients. Motion sickness was investigated in 4 experiments using 15 different conditions, with 20 subjects in each condition. They react to this oxidative stress in an adaptive way after chronic stimulation. D-Ala2-D-Leu-enkephalin (DADL, 0.5 mcg), acting on delta-receptors, was shown to potentiate nociceptive shifts of arterial blood pressure. As long-term data becomes available to support or refute the renewed enthusiasm in the more modern techniques and applications, the indications for osteotomies about the knee will become better defined. The morphologic identification of the fungus may be misleading because it shares some common features with many other dimorphic fungi. Peripheral platelet/lymphocyte ratio predicts lymph node metastasis and acts as a superior prognostic factor for cervical cancer when combined with neutrophil: Lymphocyte.

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Interaction immunoglobulin G from cancer patients with alpha-globulins. PMP frequencies of alpha EEG waves were used during application on the area of the head and a different frequency for whole body treatment focused on muscular dystonia. The power in the 5-7 Hz frequency band was found to be a good indicator of the duration of the morphine effect since the value of this index was elevated during the time course of the drug effect. Contractile responses to field stimulation, carbachol and potassium chloride were determined. Alteration in ion channel function underlies numerous pathologies, including hypertension, diabetes, chronic pain, epilepsy, certain cancers, and neuromuscular diseases. We analyzed the effect of 2 hybridoma monoclonal antibodies (Mab), D1-12 and D4-22, with specificity for common determinants of human Ia molecules, on the mixed lymphocyte culture (MLC) response. It was confirmed that, even at the same high concentrations, no mutagenic effect can be detected with the Ames test in strains TA98 and TA100 of S. A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. This study was undertaken to assess the left ventricular mass (LV Mass) and systolic and diastolic functions of the left ventricle in children with protein energy malnutrition (PEM).

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The importance of dietary iron in the pathogenesis of cirrhosis has been documented. Structural diversity of metal-organic frameworks (MOFs) has been largely limited to linkers with at most two different types of coordinating groups. In contrast choroid plexus epithelial cells attached poorly to collagen I gels. Reversal of submaxillary salivary alterations in cystic fibrosis by guanethidine. At the same time, homogeneous tuberculomas most commonly formed in both newcomers and indigenes. A study on the role of DNA methylation within hCG and hPL genes in trophoblastic disease. Treatment with immunosuppressants has opened today possibilities of clinical organ transplantation. The LPS-binding capacity of the gel was approximately 2.4 X 10(-6) g/10 ml.

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Human endothelial cell activation and apoptosis induced by enterovirus 71 infection. The management of biliary obstruction caused by Ascaris lumbricoides has usually been surgical. Ecabet sodium inhibits Helicobacter pylori lipopolysaccharide-induced activation of NADPH oxidase 1 or apoptosis of guinea pig gastric mucosal cells. Although strategic mining of electronic health records has produced real-world evidences to inform drug repurposing, using omics data (drug and disease), knowledge base of protein interactions, and database of transcription factors have been explored. Embolization of the pulmonary artery bed: hemodynamic and respiratory changes. Complex procedures requiring a high degree of precision and dexterity can be performed using an electromechanical interface specifically designed for micromanipulation. We examined whether increased XOR activity impairs vascular redox biology and causes ED in rats treated with omeprazole. An FTIR study on the adsorbed material was used to determine the possible adsorbed complex on the surface of the adsorbent. The suppression of hepatic cytochrome P4504A mRNA mediated by the interferon inducer polyinosinic acid.polycytidylic acid. The Spielberger State and Trait Anxiety Scale (STAI) and the Beck Depression Inventory (BDI) were administered to assess anxiety and depression levels.

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The percentage total desmosomal length in relation to the perimeter of a cell showed the same tendency. Creation and properties of histocompatibility antigen-cell conjugates. The intracellular distribution of cathepsins and other acid hydrolases in mouse peritoneal macrophages. Determinants for binding of a 40 kDa protein to the leaders of yeast mitochondrial mRNAs. Spontaneous migration of peripheral blood leukocytes, lymphocytes and neutrophils was studied in normal subjects. Distinct subunits of phycoerythrin from Porphyridium cruentum and their spectral characteristics. Proceedings of a Malaria Workshop held in conjunction with the Sixth International Conference on Red Cell Metabolism and Function, Ann Arbor, Michigan, October 2, 1983. We present a correction technique that uses the effective bone and tissue attenuation coefficients to compensate 99mTc-HMPAO brain SPECT projections for attenuation. Principles of educational psychology in university teaching as related to the education of medical students. The D-state: a review and discussion of studies on the physiologic state concomitant with dreaming.

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Genomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep. A case treated with circular resection of mediastinal-trachea because of stenosis after endotracheal intubation. Little is known about this association in developing countries, where fetal growth retardation is common. The antibiotics were named mannopeptin after the glycopeptide containing mannose. Aldosterone antagonism in heart failure: improvement of cardiac remodelling, endothelial dysfunction and platelet activation.

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To determine whether a link exists between RAE28 and leukemia, we examined RAE28 expression in leukemic cells from pediatric patients with B-lineage ALL. Eleven feet (nine patients) with symptomatic flatfoot deformities of various etiologies that had failed nonoperative treatment underwent distal calcaneal lengthenings. The identification of the QRS complex offset in the presence of ST segment deviation. This was a retrospective study involving 49 cases of VGAM diagnosed prenatally and managed at two centers over a 17-year period (1999-2015). Cerebral blood flow and regional potassium distribution during focal ischemia of gerbil brain. In a double-blind, placebo-controlled study the encephalotropic and psychotropic properties of both orally and intravenously administered doses of vinconate (OC 340)--a new vincamine analogue--were studied in 10 elderly subjects in their sixties by means of quantitative EEG and psychometric analyses. Differential effects of endogenous and synthetic cannabinoids on voltage-dependent calcium fluxes in rabbit T-tubule membranes: comparison with fatty acids. Ovarian fluid allows directional cryptic female choice despite external fertilization.

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Using oligonucleotide probes based on the amino acid sequence of mouse kidney ACE, cDNA encoding this protein has been isolated. The relationship between cognitive biases and psychological dimensions of delusions: The importance of jumping to conclusions. Increased pulmonary arterial pressures as a result of pulmonary disease are described in two cows with chronic pneumonia and one cow with acute pneumonia. Bench-scale batch absorption tests have been carried out to investigate odorous gas abatement for a range of selected commercial products and water at a range of pH values. The method offers a simple and specific antibody assay which could be used for the laboratory diagnosis of avian infectious bronchitis. Glutamine oxidation was closely linked to sodium transport and greatly decreased by inhibition of Na-K-ATPase. One hundred and five compensated cirrhosis patients who received pegylated interferon plus ribavirin between January 2005 and December 2011 were enrolled. The method of iron estimation used was an autoanalyzer method using tripyridyltriazine as chromogen. Our study presents, to our knowledge, the largest set of transferred embryos after time-lapse analysis with the use of an automatic time-lapse test. Using light microscopy (immunocytochemical colocalization with different pancreatic hormones), immunoreactivity to 7B2 (IR-7B2) was consistently found within cells producing insulin and glucagon and less consistently within pancreatic polypeptide-containing cells.

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The DNA content in the mentioned organs was not affected by the insulin. In the presence of an alcohol habit, the relative risk for tobacco chewing and smoking was observed to be cleocin 300 mg cost high in the non-vegetarian group compared to the vegetarian group. Importantly, Chidamide possessed potent HDAC inhibition property, as evaluated by HDAC activity analysis and acetylation of histone H3 and H4. Thus Chang hepatoma ascites cells were investigated to determine if AC could be localized cytochemically in this cell type. A combination of retrograde tracing and immunohistochemistry for tyrosine hydroxylase (TH) revealed that no SN neurons sending their axons to the RF around the Vm showed TH-like immunoreactivity. Nevertheless, ubiquitous expression of the GALV receptor, Pit-1, makes targeting desirable in order to increase the specificity of the observed cytopathic effect. The effect of norepinephrine and theophylline on blood glucose, plasms FFA, plasma glycerol and plasma insulin in normal subjects. We find that the radius of gyration and the maximum linear dimension of oxidized cytochrome c are significantly larger than those for reduced cytochrome c, in 5 mM phosphate buffer at pH 7.3, and further that this difference is suppressed by addition of 200 mM sodium chloride.

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These results extend our knowledge of heterotrophic metabolism of bacterial communities in deep-sea hydrothermal plumes. Therefore, synthetic galectin-3 inhibitors are of utmost importance for development of new antitumor therapeutic strategies. The mechanism of the gastric antisecretory action of the stimulation of central alpha-2 adrenoceptors were studied in conscious, pylorus-ligated rats using intracerebroventricularly (i.c.v.) administered oxymetazoline as the model substance. Extremely high transpulmonary pressure in a spontaneously breathing patient with early severe ARDS on ECMO. Growth hormone response to TRH indocin medication generic name in families multiply affected with schizophrenia. The taxonomic status of Echinococcus cruzi Brumpt and Joyeux, 1924 (Cestoda: Taeniidae) from an agouti (Rodentia: Dasyproctidae) in Brazil. It is concluded that coronary arteriography is indicated in these patients with mild symptoms. The human SNARE protein Ykt6 mediates its own palmitoylation at C-terminal cysteine residues. The average postoperative American Orthopedic Foot and Ankle Society score was 90 with seven excellent, three good, and one poor results.

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Increased plasma gastrin levels in connection with inhibition of gastric acid responses to sham feeding following bulbar perfusion with acid in dogs. Pleomorphic xanthoastrocytomas (PXAs) in the tectal region are exceedingly rare and have distinctive clinicopathological features. Over a 3-day period, the mussels were fed artificial diets containing Alexandrium minutum AL1V (a PSP toxin producer), Tetraselmis suecica, Ensiculifera sp1 and silt, to the levels required by each treatment. Regulation, efficiency and trainability of the vestibular system. The transcriptomic profiling was conducted with two microarray platforms: a dedicated custom array (iRIPE) and a whole genome array specifically enriched with ripening-related genes for apple (WGAA). During the past decade, significant progress adalat tablets has been made in the cloning, functional expression, and initial characterization of these transporters. The features of this case fulfil the criteria for a probable adverse drug reaction of a type and severity rarely encountered. The virus is selectively oncolytic in tumour cells, eliciting extensive cell-to-cell fusion and ultimately leading to cell death. Determination of glomerular size-selectivity in the normal rat with Ficoll. Work in this field led to the development of vigabatrin, which inhibits the enzyme responsible for the degradation of GABA.

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Dosimetric comparison between proton beam therapy and photon radiation therapy for locally advanced non-small cell lung cancer. Pertinent studies (including human and animal models) pertaining to angiogenesis of implantation and placental and embryonic development were reviewed. Changes in rates of salivary estriol increases before parturition at term. When leukotriene B4 (LTB4) was incubated with rat liver microsomal fraction in the presence of coenzyme A (CoA) and ATP, a more polar product (compound I) was detected on reverse-phase high-performance liquid chromatography (RP-HPLC). When TGFbeta1-pretreated fibroblasts were incubated with CTGF, activation of ERK1/2 MAPK signaling was observed. They simultaneously engaged in different reaction-time (RT) tasks that varied in the amount of attention required for successful performance. This review aims to summarize the current state of knowledge regarding the control of blood cell production by specific factors and to put these data in the context of clinical medicine. The results indicate that B12-mediated repression of the metE gene is primarily a loss of MetR-mediated activation due to depletion of the coactivator homocysteine, rather than a direct repression by the MetH-B12 holoenzyme. Anesthetics also modulate systemic arterial blood pressure, lung ventilation, and thermoregulation, all of which may interact with the ischemic insult as well as the therapeutic interventions.

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The sulfhydryl reducing agents commonly used in protein sample buffers (2-mercaptoethanol and dithiothreitol) were found to migrate at the electrophoretic dye front. Our results revealed combination of u534122 and u3868172 as the best reference genes across all samples. Slipped capital femoral epiphysis following ipsilateral femoral fracture. CRL, at the dose of 2 ng/kg/min, significantly augmented BE levels in the plasma, and in CSF. The tethered agonist approach to mapping ion channel proteins--toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. This spinal pattern left two regions, one anterior and one posterior to the acetabulum, devoid of spines. Evidence supporting linkage to 4 previously reported (1q23, 2q33, 16q12-13, and 17q21-23) and 4 novel (3p24, 10q23-24, 13q32, and 18q22-23) chromosome regions was revealed. Under normal circumstances, the mucosal immune system employs tightly regulated dynamic mucosal intra- and internets for the maintenance of an appropriate immunological balance between the host and gut environments.

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conorii-infected SVEC-10 endothelial cells, with peak activity on day 10. The findings are consistent with the suggestion made from studies on transmitter turnover that antidepressants by inhibiting reuptake of norepinephrine cause a stimulation of postsynaptic receptors which decreases the activity of bactrim mrsa dose the presynaptic neurons by a feed-back mechanism. The multiple-injection technique for axillary block, in which the 4 distal nerves of the plexus are located by a nerve stimulator and separately injected, has been shown to produce a rapid onset and a high success rate. In many pregnancies with fetal hyperechogenic bowel, there are multiple factors that may explain these findings. Coexistence of pemphigus vulgaris and progressive localized scleroderma.

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The counting rate limitation of this approach can be largely largely overcome by using graded absorbers to reduce scattered radiation from the patient and using not only photopeak events but Compton events in the scintillator as well. Plain radiographic examination is a fundamental approach to the diagnosis and treatment decision-making of the hip. Gynecologic cytology in Cancer Cytopathology: 20 years of massive change. All but one participant reported being satisfied with their decision plavix generic name cost to undergo oophorectomy. The in vitro development of bovine corneal opacity induced by two anionic surfactants, sodium decyl sulphate (NaDS) and sodium lauryl sulphate (NaLS), was monitored using a simple, specially constructed instrument, the opacitometer. Binding of Solvent Molecules to a Protein Surface in Binary Mixtures Follows a Competitive Langmuir Model. This includes mechanisms that attenuate proapoptotic pathways and/or amplify antiapoptotic pathways. Principles of radiation therapy in the treatment of bone metastases.

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