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Effect of cerebral ventricles perfusion with naloxone on trigemino-hypoglossal reflex in rats. Western blot analysis of PPF-treated normal human dermal fibroblast cells showed a dose-dependent increase in the expression of extracellular matrix genes such as collagen and elastin, but decreased expression of the aging gene matrix metalloproteinase-3. It is proposed that persistent methotrexate concentrations and/or the associated folate deficiency may be related to the toxicity of methotrexate, especially in time of cellular stress. In preparations stored in the cold for more than 2 days, the inhibition disappeared and in some preparations posttetanic potentiation was manifested, instead. If the mice were dosed daily (i.p.) with the H1 agonist, 2-methylhistamine, or the H2 antagonist, metiamide, the titers of reaginic antibodies on day 11 were significantly higher than the controls. In the early period of obstructive jaundice, the IL-6 level after hepatectomy did not increase in comparison to HEP group, and steroid had no effect on IL-6 level. Experimental studies on the radiation-modifying effect of bleomycin in malignant and normal mouse tissue in vivo. Correlations between protein structures and amino acid sequences are widely used for protein structure prediction. Therefore one can not reliably predict aspiration with a single saturation screening.
In this paper we present the methodology and some preliminary results of the spatial analysis of rabies positive fox cases diagnosed in Hungary between 1990 and 2001. Aortitis is uncommon but is increasingly recognized as an important cause of aortic aneurysms and dissections. Thus, the presence of the receptors for erythropoietin may be required, but are not essential for responsiveness to erythropoietin. Inhibition of short-circuit current in toad urinary bladder by inhibitors of glandular kallikrein. In each subject some kinetic parameters were calculated, including the input into and the size of the rapidly exchangeable cholesterol pool. Their spectrophotometric and kinetic properties are very similar to those of the mammalian enzymes. Safety, reliability and accuracy of small renal tumour biopsies: results from a multi-institution registry.
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In the study period only four patients developed fibrosis of the liver as shown by liver biopsies, and all four of these patients developed elevated serum PIIINP levels. Impaired gastric accommodation is one of the main symptoms in patients with functional dyspepsia. Miglitol (1) derived from 1-deoxynojirimycin is an iminosugar that is useful in the treatment of type 2 diabetes mellitus. Thus, the coincidence of photosensitivity will appear as higher if only a PPR with generalized spikes and waves is considered to be indicative of photosensitivity. The tumor was composed of discrete areas of an ordinary adenocarcinoma, a typical carcinoid tumor, and a goblet cell adenocarcinoid. Therapy was started with a dosage of 400 mg carbamazepine b.i.d. Cytosolic sodium concentration regulates contractility of cardiac muscle. Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis. Application of this topical diclofenac solution to the knee of patients with OA produced relief of symptoms equivalent to oral diclofenac, with minor local skin irritation, but significantly reduced incidence of diclofenac-related GI complaints and abnormal laboratory values.
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Therapeutic measures must involve speech therapy and/or surgery to reduce the glottal gap, allowing less air leakage and, consequently, better vocal performance. Despite increased DA levels in the striatum and nucleus accumbens as a response to L-DOPA, the treatment had no influence on general motor activity. In the other cases an aortocoronary shunt without or with resection of a heart aneurysm and various types of aorto-iliac-femoral and femoropopliteal reconstructions were performed. A retrospective analysis of data from a series of 22 patients with toxic megacolon complicating ulcerative colitis was performed in an attempt to detect factors associated with the fatal outcome of the attack. M21-L cells were stably transfected with a cDNA-encoding alpha v. Recent studies suggest benefits in lowering triglycerides and raising high-density lipoprotein cholesterol with drugs. Fetal ovarian cysts: a report of three cases managed by intrauterine aspiration. It was concluded that the VCPN consist of two types of cells, each located in a different region of the medulla oblongata and contributing to vagal cardiac reflex mechanisms in a different manner.
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A clinical questionnaire (Rintala score) was filled in by the parents. Patients with aneuploid tumors had significantly shorter survival times than did those with diploid tumors (P less than or equal to 0.001). At the same time, managed care enrollment has increased dramatically. These results suggest that BNP may participate with ANF in blood pressure control and salt and water homeostasis. Interaction of 2,4 dichlorophenol and hydrogen peroxide in the enzymatic destruction of beta-indolyl acetic acid.
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Antidepressant medications, mood stabilizers, antipsychotics, and antianxiety agents may be associated with SD related to drug mechanism of action. This method was indeed able to detect clastogenic compounds normally detected by the mouse bone marrow micronucleus test (MMC, CP) as well as a compound with labile metabolites which is not usually detected by this test (DEN). Its product, p48v-myb, is a nuclear protein of unknown function. The pressures leading to higher suicide levels among young women of Indian origin highlight the need for making appropriate forms of support and counselling available to this community. Diabetes has a significant impact on the function of tendons due to the accumulation of advanced glycation end-products in the load-bearing collagen. Mean negative log EC50 values of ISO and norepinephrine, but not fenoterol, were smaller in femoral and mesenteric strips from hypertensive rats than those from oil-water-treated rats. The ferrets inoculated with the Utah-1 strain of ADV did not develop elevated gamma globulin levels, but did have mild tissue lesions. The drug release process, in a solution of pH 7.4, was monitored by optical microscopy and UV spectroscopy. Phenotypic analysis of mice bearing targeted deletions of 11beta-hydroxysteroid dehydrogenases 1 and 2 genes. Renal insufficiency is common in adults with homozygous sickle cell disease, and the contribution of glomerular failure to the hyperuricaemia which is often a feature of the disease has therefore been investigated.
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A study of knowledge, attitude, and practice of cervical screening among female primary care physicians in the United Arab Emirates. They are involved in the key processes of photosynthesis and respiration. pDN1 is distinct from three clones of genes involved in nitrate assimilation that were isolated previously from the related cyanobacterium Synechococcus PCC7942 (Kuhlemeier et al., 1984a, J. One strategy to improve the efficacy of ErbB-targeted therapies is to inhibit multiple ErbB receptors, thereby interfering with the cooperation that exists between receptors. Through the first detailed study, we believe, on the behaviour of an ovipositing Clistopyga species, we show that it can alter its ovipositor for different purposes and that the primary function of the apical serrations is clinging to its spider host as the spider attempts to escape. To examine the mechanism of improved viability using this solution as a preservation solution, we developed a model of orthotopic small intestine transplantation (OIT) in the rat.
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This finding, in conjunction with the high incidence of spontaneous possibly malignant, lymphoproliferative disorders in these patients, may have important implications regarding the theory of immune surveillance mediated by NK cells. Median frequency of the electromyographic signal: effect of time-window location on brief step contractions. Capillary junctions of the rat are not affected by osmotic opening of the blood-brain barrier. Pulse labeling studies and Northern blot analyses showed that the decrease occurs post-synthetically. Exercise training may improve these parameters for haemodialysis patients.
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Changes in the activity of the pathological process and some neuroendocrine functions in patients with rheumatism and infectious nonspecific polyarthritis during complex sanatorial and health resort treatment. Nevertheless, enthusiasm for the pubovaginal sling is tempered by the surgical morbidity and postoperative voiding dysfunction associated with it. Contemporary issues in the management of von Willebrand disease. An ionic liquid-coordinated palladium complex: a highly efficient and recyclable catalyst for the Heck reaction. OXC had been used because of an incorrect diagnosis of focal epilepsy or generalized tonic-clonic seizures (GTCSs) of undetermined origin (no syndromic classification of the epilepsy). Histologically the tumor was a typical hepatocellular carcinoma of adult type, except in the central portion where there was gradual replacement of the carcinoma by spindle-shaped atypical cells with areas of chondrosarcomatous tissue. In vitro, the molecular chaperone Hsc70 uncoats clathrin-coated vesicles in an ATP-dependent process that requires a specific J-domain protein such as auxilin.
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Theory of the helix-coil transition in DNA considered as a periodic copolymer. The synthesis of alpha 1-fetoprotein (AFP) was measured by radioimmunoassay in tissues and fluids of 19 bovine embryos (14-46 days of gestation) and in tissue cultures of 4 pre-implantation embryos (17-27 days) by incorporation of radioactive methionine. Magnetic fields are physical, environmental agents that have been shown to produce a variety of responses in cellular and animal studies, including general changes in gene transcription. The reate of tyrosine dydrosylation in the telencephalon was significantly higher 7 hrs after dard onset than at the other three times tested. In 10 cases it was possible to compare MRI with computerized tomography as well. A novel mutation lacking the bromodomain of the transcriptional coactivator p300 in the SiHa cervical carcinoma cell line. Sixteen patients who did not have a renal calculus confirmed by either intravenous urogram or helical computed tomography were also excluded from efficacy analysis. The original tumor as well as the cell line caused marked hypercalcemia in tumor-bearing nude mice, in which a marked increase in osteoclastic bone resorption was demonstrated.
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Algorithms to correct these types of errors are being used, but they are based either on a study of frequent types of errors associated with general words in an English text rather than types of errors associated with the spelling of names, or on errors that are phonologically based. While hepatic SR-BI expression controls high density lipoprotein (HDL) cholesterol metabolism, intestinal SR-BI has been proposed to facilitate cholesterol absorption. One strategy to overcome these barriers is to activate mucosal T cells through the use of nasal vaccination because this may overcome the systemic immune downregulation that results from HBV infection. Expression of the tg beta chain on all thymocytes and peripheral lymph node T cells led to a more efficient anti-CII immune response, but did not confer CIA susceptibility to SWR/J mice. Dominant mutation for ethionine resistance in Saccharomyces cerevisae. In particular, statements regarding which avian taxa have relatively larger brains and brain regions are based on small sample sizes and statistical analyses are generally lacking. The experimental data proved the pharmacokinetic interaction between ranitidine of metoclopramide, and suggest monitoring adverse effects in patients. Surgical treatment of fractures and fractures-dislocations of the proximal end of the humerus. The purpose of this study was to evaluate the ability of velocity-encoded nuclear magnetic resonance (NMR) imaging to quantify left to right intracardiac shunts in patients with an atrial septal defect.
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We studied epidemics of viral hepatitis occurring at three different places in India. Primary structures of chicken cone visual pigments: vertebrate rhodopsins have evolved out of cone visual pigments. This observation suggest that IDH kinase and IDH phosphatase do not reside on structurally independent domains. Our study suggests that venules in actively inflamed area play an important role in eliciting and/or maintaining acute inflammatory processes by active permeation of neutrophils from the blood stream into the tissue, and that ELAM-1 may be a secretory protein as well as a transmembrane receptor protein. The diagnosis of heart disease in newborn infants presents numerous radiologic difficulties because of a variety of factors, including the frequent absence of specific radiographic signs, the confusing effects of parenchymal disease, and the difficulties encountered in identifying specific locations of chamber enlargement and even in distinguishing between arterial and venous plethora. As this article demonstrates, both fields can benefit by closer collaboration. We report 2 cases of eosinophilic cystitis induced by Tranilast, which was used for the treatment of bronchial asthma. Conformational transitions coupled to binding are studied for the p27(Kip1) protein which undergoes a functional disorder-to-order folding transition during tertiary complex formation with the phosphorylated cyclin A-cyclin-dependent kinase 2 (Cdk2) binary complex.