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These results indicate that two distinct 60-kDa proteins are substrates for the Src tyrosine kinase, one which binds RNA and the other which constitutes the major GAP-associated 60-kDa phosphoprotein. pylori-associated gastritis are not clearly defined, it is reasonable to presume that suppression of host defense mechanisms may contribute to the pathogenesis of this disease. Vitamin E increases interleukin-2 dependent cellular growth and glycoprotein glycosylation in murine cytotoxic T-cell line. Typewriter tinnitus: a carbamazepine-responsive syndrome related to auditory nerve vascular compression. Cysteine residues 17 and 19 in the M2 protein ectodomain form disulfide bonds. Both the parent or guardian and student independently completed the checklist. With the advent of biologic agents, we are better equipped to manage psoriatic arthritis today. Plasma cholinesterase activity in newborn infants with erythroblastosis foetalis. The A(H)-A(Md) interval provides an electrophysiological marker that can be used in addition to the radiological catheter position to assess the risk for AV block before onset of RF delivery.
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A phase III randomized trial comparing adjuvant concomitant chemoradiotherapy versus standard adjuvant chemotherapy followed by radiotherapy in operable node-positive breast cancer: final results. Effect of recombinant human erythropoietin on platelet production in dialysis patients. This salt bridge suggests a pathway for enzyme inactivation upon CO binding, because Arg-266 is located on a helix that connects the heme and pyridoxal phosphate cofactor domains. Dialysate glucose concentration in hemodialysis: feasibility study and microbiological aspects. The senescence-accelerated mouse (SAM) is a useful animal model to study aging or age-associated disorder. Circular dichroism spectroscopic study of non-covalent interactions of poly-L-glutamic acid with a porphyrin derivative in aqueous solutions. We conclude that the observed phenotype in the cholera toxin transgenic mice may be caused by a deleterious effect of the transgene itself on beta-cell function, or that counter regulatory mechanisms may compensate for the transgene-induced changes in intracellular enzymatic pathways. The class II molecules of the diabetes-prone NOD mice, I-Ag7, showed very limited amounts of stable form when analyzed by SDS-PAGE. Divergent regulation of proteoglycan and glycosaminoglycan free chain expression in human keratinocytes and melanocytes.
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1) Mono-L-aspartyl chlorin e6 is a photosensitizer with a molecular weight of 799.7 in which the double bond porphyrin ring has been reduced and an aspartic acid is attached to the propionic group at the carbon of the tetrapyrole ring via a peptide linkage. Three years after the repair of a true left ventricular aneurysm, a 62-year-old man was admitted to our department for spontaneous angina pectoris and heart failure. In addition, in histological examinations, massive congestion and cellular infiltration in pulmonary interstitia, and considerable haemorrhage in renal medullae were observed. Moreover, addition of TNF-alpha during stimulation resulted in augmentation of B-cell proliferation, which was also inhibited by anti-TNF-alpha monoclonal antibody. The purpose of this study was to observe differences in starting techniques of 20 championship cyclist responded significantly faster after the auditory stimulus and recorded faster 1/2-lap split times than 10 proficient cyclists. Glucose as a regulator of glycogen phosphorylase in rat diaphragm. In treated animals, degeneration and simplification of postsynaptic folds and widening of synaptic clefts were often observed in soleus end-plates, but infrequently in EDL end-plates. We used site-directed spin-labeling and electron paramagnetic resonance spectroscopy to characterize the conformational motion that couples energy expenditure to substrate translocation in the multidrug transporter MsbA. beta-adrenergic receptors enhance reuptake of potassium into muscle.
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The spore inviability of rad58 strains is not rescued by a spo13 mutation. However, since there are many similarities between these and ReA, the mechanisms established in ReA may have general relevance in understanding synovitis. This study confirmed the good intra-observer reproducibility of the variables that characterize anterior segment morphometry by UBM. To find a biological marker associated with preterm delivery or neonatal infection in pregnant women with preterm labour and intact membranes. The causes of diminution of visual function in surgically compensated glaucoma. A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells. Impact of carbon and nitrogen nutrition on the quality, yield and composition of blastospores of the bioinsecticidal fungus Paecilomyces fumosoroseus. This increased sensitivity to UV-B may be a result of the effect of calcipotriene on stratum corneum thickness, epidermal melanization, a result of its effect on the inflammatory reaction to UV-B irradiation, or, possibly, because it is a phototoxic agent. This method allows direct, high-resolution, two-dimensional chemical and immunological characterization of the cellular membranes in situ, as well as detection of sites within cross-fractured cytoplasm and extracellular matrix. Patients with posttransplant IgAN may benefit from intensifying maintenance immunosuppression, which slows progression to end-stage graft dysfunction.
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Cardiorespiratory hospitalizations associated with smoke exposure during the 1997, Southeast Asian forest fires. All three patients had intra-abdominal lymphangiomatous cysts, uterine LAM, and renal angiomyolipomas. Pediatric renal cell carcinoma: single institution 25-year case series and initial experience with partial nephrectomy. To explore the clinical value of CT-guided percutaneous needle biopsy (PCNB) for diagnosis of atypical pulmonary tuberculosis. 2 cases treated by endoscopic incision presented vesicoureteral reflux, and 4 cases treated by nephrectomy had a low grade reflux. Involvement of inflammatory reactions and elevated cell proliferation in the development of bladder cancer in schistosomiasis patients. Prognosis of facial palsy in Borrelia burgdorferi meningopolyradiculoneuritis. Video-assisted thoracic surgery (VATS) is a compromise between conventional thoracic surgery performed via a thoracotomy of variable dimensions and surgical videothoracoscopy, which, using only small operating channels, requires the use of specific instruments, gives a field of vision exclusively by video camera and raises the delicate problem of extraction of the resection specimen. The aim of the present was to study the efficacy of a standard mixed meal (breakfast test) to predict the need for insulin therapy to thereby evaluate whether it is possible to obtain more objective criteria for the indication of insulin treatment. Only four compounds showed deficiencies in labelling (anti-granulocyte MAb, HIG, HMPAO, MAG3, altogether 18 preparations).
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Adjuvant therapy of primary malignant melanoma with natural human interferon-beta. A 38-year-old Hispanic man was referred for having reduced visual acuity secondary to distorted corneas. - Lethal toxic manifestations of Candida albicans in mice were demonstrated by the intravenous injection of 10(7) viable yeast cells. The role played by muscle afferents in the somesthetic mechanisms is briefly discussed. Nevertheless it can also give rise to other manifestations, with or without respiratory involvement. Combination therapy duplicated the effects found in rats medicated with lisinopril, except that cardiac ACE2 mRNA fell to values found in vehicle-treated rats. Previous work has shown that co-incubation of human sperm with Chlamydia trachomatis serovars E and LGV leads to premature sperm death and that this is due primarily to chlamydial lipopolysaccharide (LPS). Mapping the diabetes polygene Idd3 on mouse chromosome 3 by use of novel congenic strains. Surprisingly, mammals, although acquiring a more complex general organization, seem to retain certain genome-related properties that are similar to amphibians.
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During transrectal ultrasonography, images were recorded from biopsies performed in 127 patients. the cytotoxicity of treatment and therefore drug-heat efficacy, showed that for a given level of cell killing the combination of heat and cis-platinum resulted in fewer transformants per surviving cell than for cis-platinum alone. Despite this pretreatment, cold-restraint stress still induced ulcer formation, along with changes in gastric ir-TRH and ir-SOM concentrations and gastric pH. Immunological and biochemical indices during the use of hyperbaric oxygenation for treating patients with jaw deformities. In these latter experiments, genetic analysis showed the presence of multi-locus deficiencies in 18 out of 42 w mutants. Nine consecutive adult patients stung by Androctonus australis and presenting with pulmonary edema entered the study. Changes in the fatty acid pattern of plasma fractions of rats fed coconut, olive or sunflower oil.
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The data are interpreted to indicate the reversible binding of the venom to receptors. This work establishes the role of macrophages in the delivery, expression, and possible activation of matrix destructive proteinases during AAA pathogenesis and suggests a role for the activation of MMPs in the progression of the disease. Self-reported body weight perception and dieting practices in community-dwelling patients with schizophrenia. Sensitive quantification of proteins by electrophoresis in gels by use of chemiluminescence. During the recent years, Chilean universities seem to have focused their undergraduate curricular activities into pragmatic aspects of professional practice and the relevance of involving undergraduate students in high-level scientific research receives little consideration.
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Concurrent encoding of frequency and amplitude modulation in human auditory cortex: MEG evidence. Lung cancer is still one of the main reasons for death in the western world. Series of aziridine-2,3-dicarboxylate-based cysteine protease inhibitors have been tested, most of them inhibiting rhodesain in the low micromolar range. The use of complementary methods in psychiatric patients poses various questions including compliance and ethical considerations, demanding a high flexibility and integrative thinking in psychotherapy. After birth, male rats were allowed to grow until adulthood, and then testes, epididymides, and prostate glands were investigated histopathologically. These results suggest that various nonsteroidal anti-inflammatory drugs may offer some protective influence on hypoxic rat hearts particularly with respect to coronary artery patency during hypoxic perfusion. The time-dependent inactivation of the enzyme with diethyl pyrocarbonate and its kinetic analysis strongly suggested the occurrence of histidine residue.
Thirty-eight studies met the required quality criteria and were included in this review. These results assume importance in view of the fact that these plants are used as therapeutic agents. The blood vessels are the first to be affected quickly followed by degenerative changes of the glomeruli, which are possible due to hemodynamic disturbances, results in progressive destruction of the kidneys. Calcium from extracellular sources is necessary for the sustained phase of secretion. To have grieved and accepted their situation was a prerequisite for managing, and support from the family was a help in the struggle. Cox proportional hazards regression analyses were used to examine the risk of complications in relation to the study group.
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A temperature-sensitive p53 allele (Val-135) was introduced into the Friend erythroleukemia cell line (DP-16) which lacks endogenous p53 expression. A case of multifocal choroiditis associated with progressive subretinal fibrosis. The initial heavy proteinuria promptly decreased after the prednisolone dosage was increased and disappeared 4 weeks later. The paper describes impedance methods of investigating upper urinary tracts (UUT) which may serve adjuvants in the diagnosis of the urinary tract wall disturbances due to diseases caused by impaired urine evacuation from the kidney and which may prove helpful in the choice of therapeutic policy, evaluation of the postoperative period and outcomes prognosis. GlnB was found to interact directly with the N-terminal GAF domain of wild-type NifA, but not with its central or C-terminal domain.
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