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Agulan (Aceclofenac)
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Agulan

Agulan is a medication used to treat high blood pressure, heart failure, or stable coronary artery disease. As a long-acting ACE inhibitor, it works by relaxing blood vessels and decreasing blood volume. As a prodrug, perindopril is hydrolyzed to its active metabolite, perindoprilat, in the liver.

Other names for this medication:
Aceclofenac, Acertil, Acerycal, Agulan, Aldoc, Armix, Asyntilsan, Bionoliprel, Biprel, Bipreterax, Cardipen, Coveram, Coverene, Coverex, Covinace, Domanion, Dorover, Indapril, Inopil, Midopril, Noliprel, Pendoril, Pendrex, Percarnil, Perindal, Perindan, Perindo, Perindox, Prestance, Prestarium, Preterax, Prexanil, Prexum, Prindace, Procaptan, Provinace, Reaptan, Stopress, Teraxans, Vectoryl, Vidotin

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Also known as: Aceclofenac

Description

Agulan is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking ACE, an enzyme involved in narrowing blood vessels and causing sodium and fluid retention by the kidneys. This causes blood vessels to relax, allowing blood to flow more freely and at a lower pressure, and increasing the heart's ability to pump blood in some types of heart failure. Agulan is also known as Coversyl, Perindopril, Acertil, Armix, Coverene, Coverex, Coversum, Prestarium, Prexanil, Prexum, Procaptan. Generic name of Agulan is Perindopril. Brand name of Agulan is Agulan.

Dosage

Usual Adult Dose for Coronary Artery Disease:

Initial dose: 4 mg orally once a day for 2 weeks, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Adult Dose for Hypertension:

Initial dose: 4 mg orally once a day Maintenance dose: 4 to 8 mg orally per day in 1 or 2 divided doses Maximum dose: 16 mg/day Comments: In patients treated with a diuretic, consider reducing the diuretic dose prior to starting this drug.

Usual Geriatric Dose for Coronary Artery Disease:

Greater than 70 Years: Initial dose: -Week 1: 2 mg orally once a day -Week 2: 4 mg orally once a day, then increase to maintenance dose as tolerated. Maintenance dose: 8 mg orally once a day Use: Treatment of patients with stable coronary artery disease to reduce the risk of cardiovascular mortality or nonfatal myocardial infarction.

Usual Geriatric Dose for Hypertension:

Initial dose: 4 mg orally per day in 1 or 2 divided doses Comments: Experience with doses above 8 mg is limited; administer with careful blood pressure monitoring and dose titration.

Detailed Aceon dosage information

Overdose

If you overdose Agulan and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Agulan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Agulan if you are allergic to Agulan components. Be careful with Agulan if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Agulan may lower your resistance to infection. Prevent infection by avoiding contact with people with colds or other infections. Do not touch you eyes or the inside of your nose unless you have thoroughly washed your hands first. Do not stop taking Agulan suddenly.

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A new approach is represented in the article to assess individual variability of heart rhythm in healthy subjects. The employee health service and infection control in US hospitals, 1976-1977. Using the intergenic DNA fragment as a probe and extracts from mammalian and amphibian cells, we observed the formation of a specific complex containing the CCAAT displacement protein (CDP). Agents acting at RXFP2 receptors may be useful for the treatment of cryptorchidism and infertility, whereas antagonists may be used as contraceptives. This report describes an increased incidence of neurotoxic side effects secondary to isoniazid therapy in patients with end-stage renal disease. The aminoterminal sequence of the intact artemocyanin polypeptide was determined, but no clear-cut relationships with arthropod biliproteins or other protein families could be demonstrated. Also, the inhibition of oxygen uptake by 6-(4-methylpent-3-enyl)-1,4-naphthoquinone was determined and compared with its reported cytotoxicity toward P-388 (murine lymphocytic leukemia), A-549 (human lung carcinoma), HT-29 (human colon carcinoma), and MEL-28 (human melanoma) cells. The last 6 amino acids of the former isoform change to 30 hydrophobic amino acids in the newly identified isoform that have the potentiality of being an additional transmembrane domain. The amino acid sequence of the ribosomal protein S14 of Thermus thermophilus has been determined both by automated sequence analysis of the intact protein as well as by DNA sequence analysis of the gene.

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We studied the effects of antiallergic drugs, epinastine, ketotifen, oxatomide, mequitazine and cromolyn sodium on superoxide anion (O2-) generation from rat neutrophils. All subjects were rated at baseline and after 12 months on the Life Skills Profile (LSP), a 39-item measure of disability, with scores demonstrating moderate stability. Increased survival of preimplantation mouse embryos in medium with recombinant cytokine LIF. Neutrophils dysfunction during protonix generic omeprazole the course of intra-abdominal infection. Induction of increases in intracellular cAMP by either forskolin, an adenylyl cyclase activator, or a mixture of dibutyryl cAMP (10(-4) M) and 3-isobutyl-1-methyl xanthine (10(-4) M) significantly and reversibly augmented the heat response.

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