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The natural immune response comprises a plurality of specificities, many of which do not compete for binding, whereas molecules in a mAb all compete for binding to the same epitope. The progressive morphological damage induced by radiation, documented by the scattering singlas in flow cytometry and by electron microscopy analysis of irradiated K562 cells, induced, particularly at delayed times of culture in high doses irradiated cells, alterations of the target cell surface that might prevent the correct interaction with immune cells. Fluorescence activated cell sorting on the basis of incorporation of BrdUrd, a thymidine analog, and subsequent PCR analysis revealed the presence of proviral DNA only in the BrdUrd positive cell fraction with DNA synthesizing activity. One strain stands phylogenetically isolated and may be representative of a novel genus of the family. Our findings indicate that the measurement of cICAM-1 is useful for the determination of the severity of liver disease and hepatic fibrosis. The 10th revision of the International Classification of Diseases. Kinetic characteristics of the acetylation of isoniazid and p-aminosalicylic acid by a liver-enzyme preparation. Data on the characteristics of bacterial carrier state in abdominal typhus in the Lithuanian SSR. The case of a patient who was seen for fever and the appearance of four painful, erythematous and indurated subcutaneous nodules on the anteroexternal face of the right lower extremity 15 days previously is presented. Substantial deficiencies were identified in the performance of examinations and interpretation of MR images in the Philadelphia area in 1990.
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Differences in regional brain metabolism associated with marijuana abuse in methamphetamine abusers. Confusion occurs when evaluation tools designed to discriminate between persons (determine status) are used to assess change in individual patients over time. Pancreatic calculi, chronic pancreatitis and pancreatic fibrosis in a child. Technical report: spiral CT pneumocolon for suspected colonic neoplasms. In this study, we examined the role of CR on coxsackievirus B3 (CVB3)-induced myocarditis using mice deficient in CR1/2. Ear drum movements following stimulation of the middle ear muscles. Simulation results indicate excellent agreement with corrected asymptotic estimates and appropriate test size. These results were well correlated with sequence analysis of P-gene segments, indicating high applicability of the SSCP analysis for differentiation of mumps vaccine strains not only from each other but from wild viruses. There is evidence, that a contact between the macula densa and the mesangium always exists, a contact to the vas afferens is not obligatory.
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Factors contributing to direct radiation reduction in dentistry. Recurrent aphthous lesions are suspected to be the port of entrance for the germs. Pharmacokinetic-pharmacodynamic relationships in phase I/phase II of drug development. Low-dose IR inhibited the phosphorylation of p70(S6K), a molecule downstream of the mammalian target of rapamycin associated with autophagy in M059J cells but not in M059K cells. There was a statistically significant decrease in Alpha Hemolytic Streptococci and Neisseria species post radiotherapy. To compare in vitro ultrahigh-resolution optical coherence tomography (UHR OCT) cross-sectional images of the pseudophakic human autopsy eye with histology to evaluate the potential of this imaging technique for enhanced visualization of the anterior segment, especially the capsular bag, intraocular lens (IOL), and posterior capsule opacification (PCO) formation after cataract surgery. Should perinatal post mortems be carried out by specialist pathologists?. The Keneba babies grew much faster than American babies during the first 3 months of life, but much more slowly during the 2nd half of the 1st year. The chest pain disappeared after the endoscopic removal of larva.
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None of the variables were effective predictors of aggression for intoxicated females. There is a strong need for new, better approaches to improve survival, symptom control and quality of life. Effect of blood-membrane interactions on solute clearance during hemodialysis. Characterization of trace metal particles deposited on some deciduous tree leaves in an urban area. The influence of birth weight and genetic factors on lipid levels: a study in adult twins. The effect of chlorpromazine on the incidence of epileptic phenomena during insulin coma therapy. In addition, overexpression of Sp1 in Sp1-deficient cells results in the dramatic activation of the histone promoter. The recombinant adenovirus might be an attractive candidate vaccine for preventing the disease associated with PCV2 infection.
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Extrapituitary actions of gonadotropin-releasing hormone: stimulation of insulin-like growth factor-binding protein-4 and atresia. Fludarabine induces apoptosis in chronic lymphocytic leukemia--the role of P53, Bcl-2, Bax, Mcl-1, and Bag-1 proteins. Subsequently, one rabbit was evaluated with this system after 5 days of intravenous AmB administration (1 mg/kg/day) and AmB concentrations measured by RRS were compared to those measured by high-performance liquid chromatography (HPLC). Cytogenetic evidence that carcinoma in situ is the precursor lesion for invasive testicular germ cell tumors. Dramatic neurological improvement occurred shortly after initiation of i.v. A community based, patient-centred, longitudinal medical curriculum. Genetic analysis of three loci homologous to human G9a: evidence for linkage of a class III gene with the chicken MHC. Interferon gamma up-regulates alpha 2 macroglobulin expression in human astrocytoma cells.
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The performance was tested using 11386 EST sequences and 511 partial-length cDNA sequences. The maturation process prepares the cells to actively participate in the inflammatory and immune responses, and many factors have been reported to be involved in the process. Results of the initial histologic evaluation were compared between the main diagnostic groups and in RA patients histologic data was correlated with clinical and radiologic outcome measures. Treatment of hypertensive cerebellar hemorrhage--surgical or conservative management?. Plasma from pregnant SHRs produced a significant reduction of blood pressure in male and female SHRs, but the plasma from male and non-pregnant female SHRs failed to reduce blood pressure. New surgical technique for repair of ventricular septal perforation. Optimal combination chemotherapy and chemoradiotherapy with etoposide for advanced cervical squamous cancer cells in vitro. By plotting female reproductive strategies, as reflected in ovarian developmental type, on the molecular tree, we also demonstrate a phylogenetic trend toward increasing fecundity. Three individuals with developmental disabilities were exposed to a series of assessment conditions to identify the source of reinforcement for their self-injurious behavior. Examination of cancer incidence in British, Irish and southern-European migrants in South Australia during 1977-1978, relative to the non-migrant population, shows a high risk of stomach cancer in all these migrants and a low risk of colon cancer in southern-European migrants.
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The sample sizes required to detect linkage by using different classes of affected relative pairs are compared, and the problem of combining data from different classes of relatives is discussed. In contrast to the experiments using ribitol as the substrate, the isomerization of d-arabinose resulted in the induction of d-ribulokinase with dehydrogenase-negative cells. Complementary experiments made with fluids having all the same viscosity but different responses to elongational stresses (PEO-based Boger fluids) suggest an important role of the elastic properties of the PEO solutions on the faster drainage. The vascularized iliac bone grafts are safe implant-bearing areas and allows a reliable and predictable restoration with dental implants. Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo. The antithrombotic effects of low-molecular-weight heparins, given as adjunctive therapy to alteplase and aspirin, have not previously been compared with those of unfractionated heparin in experimental models of coronary artery thrombosis. The SurgASSIST Computer Mediated Stapler (Power Medical Interventions, New Hope, PA, USA) is a new technology that changes surgical stapling. The findings presented in this report are of general interest for the development of survey instruments for alcohol use disorders.
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The slow-phase OKN velocity followed stripe and random dot patterns almost immediately after the onset of the stimuli at 20 deg/sec. (2) In every listening condition, both groups required significantly greater signal-to-noise ratios to perform equally well on the Nonsense Syllable Test as on the Hearing-In-Noise Test-Children. The ultrastructural changes of uraemic pancreatic disease bear no resemblance to the changes seen in pancreatitis. As illustrated with the present case, serological testing may reveal an early, quick, and simple diagnosis in a case of rhabdomyolysis after a viral illness. However, it was unknown whether IKKbeta itself, or its downstream target, NF-kappaB, plays major roles in insulin resistance. Patients exposed to quartz dust had some special morphological picture of affected lymph nodes: periadenitis, dust caseosis and tubercula in the presence anthracosilicosis sclerosis. Impaired balance may result in bone demineralization, decreased bone mineral density and cause osteopenia and osteoporosis. However, genomes that vary considerably from the predominant species can be present at significant levels. DEM caused a deleterious effect on the healing of gastric lesions, probably by reducing the mucosal SH.
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Monoclonal antibody AE1 detected a 45 kDa cytokeratin in extracts of DMBA-treated epithelia that was not detected in untreated epithelial extracts. Multicystic epididymes and seminal vesicles in a patient with polycystic kidney disease. Pressure measurements in the retial efferent arteries supplying the brain revealed relatively nonpulsatile pressure profiles. Physico-chemical characteristics of the Barinas nut (Caryodendron orinocense Karst. Real-time measurement of pulse wave velocity from arterial pressure waveforms. Utilization of advanced practice nurses in healthcare systems and multispecialty group practice. The leukemogenic cell line diminished or lost the leukemogenic and leukocytosis-inducing activities during prolonged culture in vitro. gamma-Glutamyl-S-(octyl)cysteinyl-glycine (TER 143) DEE potentiated mitomycin C (MTC) toxicity in HT4-1 and SK VLB cells while TER 117 DEE did not. Periodontopathogens in elderly Chinese with different periodontal disease experience.
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In fact, systematic combination therapy may have contributed to the overuse of antibiotics and to the emergence of MDR microorganisms. Our data identify astrocyte-derived ATP as the endogenous factor responsible for microvesicle shedding in microglia and reveal the mechanisms by which astrocyte-derived ATP triggers IL-1beta release from these cells. LVMi, 24 hr BP monitoring, ECW, determined with electrical bio-impedance, biochemical correlates and spKT/V were studied at the beginning of the study and 6 months later. Effects of extradural anaesthesia on interleukin-6 and acute phase response to surgery. Although parvalbumins are generally viewed as intracellular Ca2- buffers/transporters, avian species express two thymus-specific isoforms that may play alternative biological roles. Adverse events in rheumatoid arthritis patient with etanercept therapy: the appearance of osteomalacia. We found no evidence that mutation in GUCA1B,GNGT1,or RGS9 gene is a cause of retinitis pigmentosa. Desire for hastened death, cancer pain and depression: report of a longitudinal observational study. Skin cancer control practices among physicians in a university general medicine practice.
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Clinical spectrum, conditional latency distribution, and survival. These findings provide evidence against the notion that the endogenous opioids are involved in mediating the reinforcing properties of nicotine in smokers under normal conditions. The Farm Family Exposure Study was initiated to characterize pesticide exposure to farm family members around the time of one pesticide application in a manner that will facilitate exposure assessment in epidemiologic studies of pesticides. The extant literature did not permit any hypothesis regarding the effect of response complexity on LRP latency. Effects of 0.48, 0.956, 1.195, 2.39, and 4.78 microM AII and time delays of 30, 60, 90, and 150 min with the 4.78 microM dose were determined. Patient satisfaction after laparoscopic antireflux surgery: community achievement. The IgH genes were found to be hypermutated at diagnosis, but no further hypermutation occurred during the course of the disease.
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Therapy experiments were performed using anti-p15E antibodies 19F8, which recognizes both cell surface-associated as well as circulating p15E, and ER-IS5, which did not react with surface-bound p15E beyond background, but which neutralizes circulating p15E. Because of the strict control over subject selection and dietary intake plus the absence of the increase following treatment, we conclude that the higher levels of nitrate and nitrite reflect endogenous generation of nitric oxide resulting from liver fluke infection. There have been no reports of long-term disease-free survivors using any currently available salvage regimen. An upper gastrointestinal barium study showed a polyp located in the second portion of the duodenum. Among children with chronic constipation, overweight individuals seem to constitute a distinct clinical group. Quantitatively, the disposition index, which derives from the non-linear hyperbola-like curve, provides an integrated figure of glucose tolerance including both insulin sensitivity and secretion. Quantitative analysis of topoisomerase IIalpha to rapidly evaluate cell proliferation in brain tumors. This approach will allow direct study of the constraints governing RNA evolution and allow inquiry into how the last common ancestor of extant life apparently came to have very complex ribosomal RNAs that subsequently were very conserved. There has been a dichotomy between virological and immunological viewpoints in understanding HIV-mediated cytopathicity, the former emphasizing a killing of infected cells by HIV-1 and the latter emphasizing indirect mechanisms wherein HIV or its soluble component(s) alter CD4 T-cell function and induce susceptibility to apoptosis. Despite small differences in the substate populations for the two residues, the motions may be loosely coupled as indicated by the high-resolution structure.