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Adiff (Adapalene)

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Adiff is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adiff belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Precose, Robaxin, Chloromycetin, Abilify, Dostinex, Flagyl

Also known as: Adapalene


Adiff is a third-generation topical retinoid primarily used in the treatment of acne. Adiff is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adiff gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adiff works under the skin surface to unclog pores and clear up pimples. Adiff is also known as Adapalene, Adapen, Adaferin. Generic name of Adiff is Adapalene.


It is very important that you use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin.

Do not apply this medicine to windburned or sunburned skin or on open wounds.

Do not use this medicine in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once.

Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (gel): For acne: Adults and teenagers—Apply a small amount as a thin film once a day, at least one hour before bedtime. Apply the medicine to dry, clean areas affected by acne. Rub in gently and well. Children—Use and dose must be determined by your doctor.


If you overdose Adiff and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Adiff are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Heart transplantation techniques in complex congenital heart disease. One hundred fifty-eight women with symptomatic uterine fibroids underwent UAE. To establish mouse lymphoma EL4 tumor-bearing mouse models in wild type C57BL/6 mice and nude C57BL/6 mice respectively, and to further investigate the immunological mechanisms of anti-tumor effect of melphalan. Characterization of molecular linkages placed between zeolite microcrystal monolayers and a substrate with X-ray reflectivity. Species-specific antennal responses to tibial fragrances by male orchid bees. In anesthetized 2-week-old rabbits, acetazolamide (10 mg/kg i.v.) increased HbO2 and tHb, concomitant with an increase in tissue PCO2, and decreased HbR only at 5 and 10 min. The latter made by a mercury sphygmomanometer indicated that the antihypertensive and negative chronotropic effect of Bisoprolol in a dose of 10 mg remained 24 hours after its administration and it did not significantly differ from that of the two other agents given in the above doses. Although distribution patterns in sessile marine organisms have frequently been attributed to functional characteristics interacting with wave-induced water motion, similar evidence for mobile organisms is lacking. PL017 and dynorphin A1-17 were shown previously to cause a marked increase and a profound decrease in body temperature (Tb), respectively. The present physiognomy of diabetes mellitus in the course of iodiopathic hemochromatosis.

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26 patients with affective psychoses, 11 with the unipolar and 15 with the bipolar form of the disease, 102 first-degree relatives and healthy controls matched for age and sex were examined for their platelet MAO activity. Experimental neonatal autoimmune myasthenia gravis: an immunohistochemical, ultrastructural and electrophysiological study of the motor end-plate. Many of these genes have not been previously implicated in cardiovascular disease. Fibroblasts exposed to sublethal radiation showed upregulation of b-FGF, HGF and SCF. The inherent advantage of this system is the programming flexibility offered by the microcontroller. Examination of a biopsy specimen revealed thymic squamous cell carcinoma. Current methods of evaluating tumor cell kinetics provide data quickly, so this information could impact treatment decisions. Mutation of the two tyrosines results in loss of biological function, as shown by abrogation of the transforming activity in the oncogenic counterpart of the receptor.

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Corrective surgery of the osteocartilaginous structure of the nose in its functional trends. Single-dose radiotherapy (6 Gy): palliation in painful bone metastases. Correcting anemia with Epoetin alfa is an important step in improving compromised left ventricular function. The findings regarding sex and NTD in a series of midtrimester fetuses are reviewed, and then analysed in terms of the recent hypothesis that during embryogenesis of the human neural tube there are multiple closure sites, rather than a single zipping up process. Diethylene glycol (DEG) is a well-known metabolic and renal toxin usually ingested accidentally as an ethanol substitute or as a contaminant in various medicinals.

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