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Actapin (Amlodipine)
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Actapin

Actapin is a calcium channel blocker medication used to treat high blood pressure and coronary artery disease. While not typically recommended in heart failure, Actapin may be used if other medications are not sufficient for treating high blood pressure or heart-related chest pain.

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Amlodin, Amlodinova, Amlotens, Amlovas, Anlodipin, Apitim, Astudal, Cardivas, Coroval, Dilopin, Dilotex, Eucoran, Gensia, Intervask, Lodipar, Lodipine, Noloten, Nolvac, Orkal, Pelmec, Pinam, Stamlo, Tenox, Terloc, Theravask, Vasocal, Vasopin, Vazkor

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Also known as: Amlodipine

Description

Norvasc (amlodipine) is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow.

Norvasc is used to treat chest pain (angina) and other conditions caused by coronary artery disease.

Norvasc is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Amlodipine is for use in adults and children who are at least 6 years old.

Dosage

You should take it by mouth. It is better to take Actapin once a day at the same time. Actapin treats angina and hypertension diseases and can be used both by adults and by children. Children of 6-17 years: Starting dosage is 2.5-5 mg. People with vasospastic angina or coronary artery disease: Starting dosage is 5-10 mg. Elderly people, people with hepatic: Starting dosage is 2.5 mg. If you want to achieve most effective results do not stop taking Actapin suddenly.

Overdose

If you overdose Actapin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Actapin overdosage: fainting, dizziness, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Actapin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Norvasc if you are allergic to amlodipine.

To make sure Norvasc is safe for you, tell your doctor if you have ever had:

liver disease; or a heart valve problem called aortic stenosis.

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether Norvasc will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby.

Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breastfeeding.

Norvasc is not approved for use by anyone younger than 6 years old.

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Neurite extension and increased expression of RI cyclic AMP-binding protein in ouabain-resistant neuroblastoma mutants. Unless the intervention is targeted to only high-risk subjects, cancer prevention trials should be implemented in the general population. Sequential staining of tissue mast cells first with conjugated avidin, and then with a metachromatic stain demonstrated that both techniques identify the same mast cell granules. Correlative investigations on the inclination of the subjective vertical and horizontal before and after stereotaxic procedures, with special regard to the target point. Cytoplasmic localization during testicular biogenesis of the murine mRNA for Spam1 (PH-20), a protein involved in acrosomal exocytosis. TEM could not, on the formalin fixed specimens, determine whether PAS-negative PML had a higher protein turn-over, but the findings indicate that corneal ulcers with PAS-negative PML contain a high amount of proteases, because of many degranulated PML and probably a reactivation of PML. A working model for the self-association of bile salts is proposed. Leukocyte Lysis and Cytokine Induction by the Human Sexually Transmitted Parasite Trichomonas vaginalis. The paper ends with a demonstration of the close relationship between prevention and treatment of hypertension as well as between hypertensive and ischaemic heart disease at the same time in a sense of the integrative role of heart insufficiency.

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We investigated whether there is a difference in timing between the sexes of mouse embryos with regard to digit and palatal formation at midgestation by using a simple method of sex chromatin analysis for rodent embryos. We reviewed the clinical records of 57 patients with advanced NSCLC who had received 250 mg/day gefitinib at our hospital between November 2000 and May 2003. The aim of the study is to evaluate and compare the outcomes of wireless mobile device (Telemonitoring) with Pharmacist intervention and usual care on glycemic control and clinical outcomes. The technical difficulties encountered at the time of operative intervention in uncomplicated course of the disease can be conditioned by constitution of a patient, or peculiarities of the pathological process. The majority of studies have not identified clear differences in platelet alpha 2-adrenoceptors between drug-free depressed patients and control subjects, nor have they identified unequivocal effects of antidepressant treatments. We have determined the base sequence of the restriction fragment Bam1-2 (3,593) of Paracentrotus lividus (sea urchin) mtDNA. The hematologic malignancy unit in an academic medical center in the United States. Characterization of the giant cells in the abdominal and parietal ganglia of the giant snail Archachatina. Fusion was blocked by adding neutralizing antibody to the Vero-VSV complexes. Consistent with this phenotype, gcl protein specifically associates with those nuclei that later become the nuclei of the germ cell precursors.

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The simultaneous activation hypothesis: explaining recovery from deep to phonological dyslexia. Theory of spatially uniform fields, assuming the four-point property. To study the developmental regularities and heterogeneity of mast cells (MC) in human fetus duodenum and the distribution and developmental regularities of substance P(SP), calcitonin gene-related peptide (CGRP)-immunoreactive (IR) peptidergic nerves in fetus duodenum, as well as the relationship between MC, SP and CGRP- IR peptidergic nerves. It is concluded that certain responses to splanchnic nerve stimulation are significantly potentiated by an intermittent high-frequency pattern of stimulation, including all those that are attributable to adrenal medullary activity, whereas others are apparently unaffected by changes in stimulus pattern. Use of a simple suture to stabilize the chevron osteotomy: a prospective study. However, treatment from the day before infection also caused a significant decrease in epithelial defect two days after infection. Bone reactions adjacent to titanium implants subjected to static load. The serum ferritin values showed no relationship to tumor stage, and no difference in nonseminomatous and seminomatous tumors. The ethylketocyclazocine (0.3 mg/kg)-induced behavioral effects were antagonized by naloxone (1 and 2 mg/kg).

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Recent evidence implies that KIF1A, a synaptic vesicle motor, moves processively. Development of selected coagulation factors and anticoagulants in preterm infants by the age of six months. In this study we have investigated the effects of the small GTP-binding-protein Ras on the redox signalling of the human neuroblastoma cell line, SK-N-BE stably transfected with HaRas(Val12). Odds ratios for cancer in the presence of administration of pethidine or of intramuscular vitamin K. On the basis of the amino acid (aa) sequence of the putative BTF3 transcription factor, two complementary DNAs coding for the two proteins, BTF3a and BTF3b, have been cloned from a HeLa cell cDNA library. In one instance two copies of the 152-bp repetitive sequence are separated by a 436-bp central region and are in an inverted orientation with respect to one another, resembling a compound transposable element.

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A microtechnique is described for agglutination typing of Haemophilus influenzae. Similar results were obtained with mRNA for BG1, a non-peroxisomal enzyme that is highly expressed in nervous system, adrenal gland, and testis, the principal tissues pathologically affected in X-ALD. An elevated alpha feto-protein on antenatal screening had been misconstrued as fetal in origin. These results cast doubt on the conclusions about the relative potency of tuberculosis vaccines evaluated by different methods. The efficacy of telemedicine in the delivery of dermatologic care is reviewed. A pathophysiological relationship between PTE and SAS was not found in this study. The inferior parathyroid glands were grossly unremarkable, and incisional biopsy specimens were histologically normal (no foci of water-clear cells were identified). DNA hairpins containing five or more adenosine residues in the loop are able to bind to complementary oligonucleotides covalently bound to cellulose. In the isolated rat liver perfused in situ, stimulation of the nerve bundles around the hepatic artery and portal vein caused an increase of glucose and lactate output and a reduction of perfusion flow. The burnout syndrome denotes a constellation of physical fatigue, emotional exhaustion, and cognitive weariness resulting from chronic stress.

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Clinical records of 48 patients who died suddenly and unexpectedly following coronary care unit discharge were analyzed. Treatment of plasmid DNA (pBR322) with iron(III) results in the conversion of the covalently closed circular form of the plasmid to open circles and ultimately to the linear form. This article describes the use of a half pipe cannula for changing instruments in shoulder arthroscopy without using a closed cannula system. Dopamine attenuates the effects of GABA on single unit activity in the globus pallidus. Rise in inulin-sensitive B cells during ontogeny can be prematurely stimulated by thymus-dependent and thymus-independent antigens. Effects of positive end-expiratory pressure on gastric mucosal perfusion in acute respiratory distress syndrome. On the other hand in corpus we found a normal mucosa more often among patients from Non-European countries, especially from Asia and Africa and in age group 40-49 years. During the period from 1963 to 1970, 318 patients were subjected to early operation for acute cholecystitis. Urinary continence and pathological outcome after bladder neck preservation during radical retropubic prostatectomy: a randomized prospective trial. A large-bore Teflon tube with side holes was used for nonsurgical palliative bile drainage in eight patients with malignant tumors.

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Then we determined the enhancement capabilities of Zika virus-immune serum for dengue virus in vitro. The electronic health records of all patients with at least 12 months clinical follow-up were searched for demographic information, injury details, preoperative imaging findings, post-operative complications, and ability to return to duty following surgical repair. High prevalence of macrosomia did not explain the elevated risk of perinatal and infant mortality in Cree communities. This paper presents a simple and versatile method by which pumping test procedures developed for vertical wells can be applied to horizontal well pumping tests. Effect of trichothecenes on growth and intracellular pool size of Mycoplasma gallisepticum. Two implants and three grafts were nonunited, possibly due to lack of fixation or the orientation of the histology sections. Clinical experience with a new assay for LDH and LDH isoenzyme activities. Palliative care for CHF patients is a neglected topic in both practice and research and should receive more attention. Close relation between fetal thymidine kinase and thymidylate kinase activities in breast cancer. Tallysomycin S10b was less toxic than tallysomycin A in terms of acute and subacute LD50 values.

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Absolute configuration of acyl-2,6-xylidines were selected for pharmacological examinations. Litchi chinensis fatty acid diversity: occurrence of the unusual cyclopropanoic fatty acids. The apolipoprotein concentrations appear very useful indicators of functional liver recovery. Histology of the tumor revealed the trabecular type of a hepatocellular carcinoma with Edmondson grade 2 atypism, whereas the non-cancerous region of the liver showed chronic inactive hepatitis. Human hypersensitivity to a sham vaccine prepared from mosquito-cell culture fluids. By taking into account base-base stacking interactions we improve the Generalized Model of Polypeptide Chain (GMPC). Concordant positive and negative findings were found in 158 samples but 10 produced discrepant results. Usage report of pharmacopuncture in musculoskeletal patients visiting Korean medicine hospitals and clinics in Korea.

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Finally, LCMT-1 homozygous knock-out MEFs exhibited hyperphosphorylation of HDAC3, a reported target of the methylation-dependent PP4R1-PP4c complex. The polychemotherapy consisted of procarbazine, ifosfamide, etoposide, methotrexate, cisplatin and cytosine arabinoside. An user-independent evaluation of the induced fluorescence intensity was achieved by means of the described optical system and digital imaging. Following deafferentation of the cerebellum, substance P-accumulating fibers are observed only ventral to the lesion (i.e. Pseudolymphoma of the stomach is a benign proliferation of lymphoid tissue which can be mistaken histologically for malignant lymphoma. On the clinical and etiopathogenetic interpretation of acute bulbar nucleo-reticular vestibular syndromes. This technique holds the promise of successful computer-based drug design before bound crystal structures are even discovered, which can mean a jump-start of 1-3 years in tackling some medically relevant systems with computational methods. Effect of estradiol and testosterone on vaginal epithelium of mice of different ages.

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Cytogenetic studies on patients with leukemia and RAEB found in atomic bomb survivors. However, on the basis of recent molecular data of cultured free-living and noncultured episymbiotic members zyrtec allergy medicine review of the epsilon subdivision of Proteobacteria and earlier carbon isotope data of primary consumers, an alternative autotrophic pathway may predominate. We have recently shown that rats behaving in social settings produce high rates of ultrasonic vocalizations during locomotion bouts. Findings indicate for the range of settings where videoconference approaches can be used, and for their applicability and acceptability, providing an alternative to current cognitive assessment methods. Mean O2 consumption was 1.46 ml O2/kg/m for the unaccustomed paraplegics who had never used long-leg braces before, 0.61 for paraplegics used to walking with braces, and 0.83 for the healthy subjects walking between parallel bars with a swing-through gait. brucei - depends on their uptake by and development within their tsetse fly vectors. In addition, the removal rates of cadmium ions based on the Langmuir models have been investigated. Genotypes of respiratory syncytial virus group B identified in Uruguay. The drug was specific for neutrophils as determined by differential cell counts.

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Here we have cloned ard gene into high copy vectors pBR322 and pUC12. In vitro and in vivo studies reveal contradictory evidence of the clinical performance of direct and indirect resin composite restorations in posterior teeth. Part of the challenge is the genetic and molecular heterogeneity of colorectal tumors not only among patients, but also within tumors. We found that expression of the ER DNA binding domain is highly toxic to E. Automated full-field perfusion image analysis was used to analyze the flow data. Testosterone and androstenedione are metabolized by 5 alpha- and 5 beta-reductases to androsterone (A) and etiocholanolone (E), respectively. The variations of PRL, LH, FSH and testosterone in renal disease. To estimate the risk factors associated with onset of urinary incontinence in a rural community-dwelling elderly population. Thumb and fingertip reconstruction by composite microvascular tissue from the toes. There is no significant difference between right-sided and left-sided antral follicle counts within the same individual.

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Comprehensive repeatome annotation reveals strong potential impact of repetitive elements on tomato ripening. Furthermore, an organic solvent system of benzene and ethanol in which gramicidin has a unique conformation is identified. Is argon plasma coagulation an efficient treatment for digestive system vascular malformation and radiation proctitis?. Psychoneurologic research needs in evaluation of patients with cerebrovascular accidents. The pedigree was cousin marriage, and three out cozaar 50 mg dosage of four siblings developed parkinsonism in their 2nd or 3rd decade. Characteristics of A-type intracytoplasmic particles produced by human cells. Low carbohydrate high fat diets: when models do not match reality.

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