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Actalipid (Simvastatin)
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Actalipid

Actalipid is a cholesterol-lowering medication which used to treat high cholesterol levels in the blood. It works by blocking the production of cholesterol in the body, thus can help prevent conditions that can lead to heart attack, heart disease and hardening of the arteries, stroke, and vascular disease. This medication can also reduce these risks in people with diabetes, peripheral vascular disease, and a history of stroke. Use this medication during low fat diet to get the best result.

Other names for this medication:
Actalipid, Docsimvasta, Dosavastatin, Lipex, Lipinorm, Lodales, Normotherin, Simbastatin, Simgal, Simvastatin, Simvastatina, Simvastatinum, Simvofix, Sinvacor, Sivastin, Statinal, Vasilip, Zocord, Zorced, Zorstat, Zosta, Zostin, Zostine, Zovast, Zovastin, Zovatin, Zurocid

Similar Products:
Zyvox, Glyburide, Artane, Clomid, Parlodel, Tricor

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Also known as: Simvastatin

Description

Actalipid is an HMG-CoA reductase inhibitor. Actalipid is used to: reduce the risk of heart attack, stroke, and death due to coronary heart disease; reduce the risk of heart attack, stroke, blood vessel blockage, or chest pain caused by angina; low high cholesterol and triglycerides; increase high-density lipoprotein (HDL, "good") cholesterol levels. Actalipid is also known as Imvastatin, Simlup, Simcardis, Ranzolont, Simvador. Actalipid works by reducing the production of certain fatty substances in the body, including cholesterol. Generic name of Actalipid is Simvastatin. Brand name of Actalipid is Actalipid.

Dosage

Take Zocor exactly as prescribed. Follow all directions on your prescription label. Never take this medicine in larger amounts, or for longer than prescribed. Taking too much of this medication may cause serious or life-threatening side effects.

Zocor is usually taken at bedtime or with an evening meal. If you take this medicine more than once daily, take it with meals. Your doctor may occasionally change your dose to make sure you get the best results.

While using Zocor, you may need frequent blood tests at your doctor's office.

You may need to take Zocor on a long-term basis for the treatment of high cholesterol. You may need to stop using this medicine for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Zocor is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture, heat, and light.

Detailed Zocor dosage information

Overdose

If you overdose Actalipid and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actalipid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Actalipid if you are allergic to Actalipid components. Be careful with Actalipid if you're pregnant or you plan to have a baby. Do not use it if you are a nursing mother. Be careful with Actalipid if you suffer from low blood pressure, kidney problems, diabetes, serious infection, metabolism problems, hormonal problems. Do not use potassium supplements or salt substitutes. Avoid eating grapefruit or drinking grapefruit juice while taking Actalipid. While taking Actalipid, you can make laboratory tests (blood cholesterol levels, liver function tests, creatine phosphokinase blood levels) to monitor the condition of your health. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Be very careful when you are driving machine. Do not stop taking Actalipid suddenly.

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We have tested whether this structure exhibits similarity to the nuclear lamina of metazoic organisms. This article summarizes data on translational studies to target the p53 pathway in cancer. Health, a strong force for world understanding: the role of the physical therapist. The results are maintained longer than 1 year, and no evidence of significant resorption of the fat was found in our study over a period of 12-58 months. frugiperda larvae, causing damage to their reproductive histophysiology and results in diminished reproduction or reproductive failure. We monitored 210 hospitalized ICU patients during a 12-month period. Italian scientists and institutions participated from the very beginning in fundamental and applied research aiming at exploiting the potentialities of this technique and providing relevant methodological advances and new fundamental indications. Impact of smoking status on outcomes after concomitant aortic valve replacement and coronary artery bypass graft surgery. CLINICO-PATHOLOGIC STUDY ON THE PERIPHERAL NERVOUS SYSTEM OF THE AGED. Draft genome sequence of a caprolactam degrader bacterium: Pseudomonas taiwanensis strain SJ9.

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Meta-ethnography was used to inform the review, and 21 studies were included. Anomalous diffusion and response in branched systems: a simple analysis. To identify the types of studies of nursing taxonomies and priority research themes presented at AENTDE conferences between 1996 and 2012. Ebf1 targeted disruption affects postmitotic cells that leave the subventricular zone (SVZ) en route to the mantle: they appear to be unable to downregulate genes normally restricted to the SVZ or to activate some mantle-specific genes. We examined associations of the rs146052672 SNP with T2DM, plasma lipids, lipoproteins, and body mass index (BMI). Respiratory assessment is recommended prior to, and just after starting GH treatment. Bovine blood components: fractionation, composition, and nutritive value.

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Use of the Actinobacillus actinomycetemcomitans leukotoxin promoter to drive expression of the green fluorescent protein in an oral pathogen. Over the past decade, research has attempted to disentangle pre- and post-substance use effects on brain development by using sophisticated longitudinal designs. Children with DEL had a smaller cerebellum, and smaller cortical and subcortical grey matter volumes. Correlations comparing didactic and practical scores were done for the total samples, then for the males and females separately. A 50-year-old Chinese man presented with abdominal pain associated with bloody mucoid stools, loss of appetite and weight loss. During aging, there are qualitative and quantitative modifications of proteins in various tissues. DETERMINATION OF UTERINE MUSCLE FLOW BY LOCAL XENON-133 LOCAL INJECTION. Consistent with past research investigating hemispheric asymmetry and attentional scope, the current results suggest that manipulating left (right) hemisphere activity enhanced local (global) attentional processing. A direct correlation between the induced expression of Ia by the host keratinocytes and the infiltration of donor Langerhans cells (LC) into the epidermis was demonstrated in athymic (nude) BALB/c mice that received an adoptive transfer of lymphoid cells from normal semi-syngeneic donors. This approach is useful to characterize changes in the acetylome in response to biological interventions (Schwer et al., Aging Cell 8:604-606, 2009).

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Using Exenatide Twice Daily or Insulin in Clinical Practice: Results from CHOICE. The method for determining glycosylate serum proteins is based on the ketoamines property (fructosamine) of reducing nitro-tetrazoline blue, in alkaline medium, to a coloured, photometric product. Assessment of an aqueous seed extract of Parkia clappertoniana on reproductive performance and toxicity in rodents. To test the hypothesis of increased frequency of HLA-B35 in self-limiting, unclassified rheumatism (SUR). Time of onset of the nocturnal increase in melatonin did not differ between clinical responders and nonresponders, suggesting that a phase advance in the onset of nocturnal melatonin secretion is not sufficient to induce clinical remission in seasonal affective disorder.

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Towards Therapeutic Delivery of Extracellular Vesicles: Strategies for In Vivo Tracking and Biodistribution Analysis. Carpet treatments can reduce mite-derived allergen levels in airborne and carpet dust. An extracellular inhibitory substance produced by the marine Alteromonas strain P-31 (NCMB 2144) was isolated and purified. Emission rates are driven primarily by energy losses, not by the difference between marginal emission rates during battery charging and discharging. Responses following electrical stimulation of anterior lobe of cerebellum in cat. Wound healing and transwell assays were used to examined the migration and invasion abilities of ovarian cancer cells. Virucidal effect of acidic electrolyzed water and neutral electrolyzed water on avian influenza viruses. Two simple balance scales comprising three or four familiar tests of static balance were developed, and their validity and reliability are described. Nonetheless, in clinical practice, there are some patients exhibiting a vitamin C deficiency as a result of an unbalanced diet or intestinal malabsorption.

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Further, we examine the potential modulatory effects of engaging in RNT immediately prior to CBM-I. Acne vulgaris is androgen dependent but the hormonal mechanisms are unclear. Gravity of functional and structural damages--apart from minor differences--showed close cinnection with the severity of tissue alterations. The M(r) 18,000 acrosomal protein aggregates negatively charged (but not neutral) large unilamellar liposomes and renders them permeable to internal probe. Histopathologic observations in a case of chronic occupational mercury poisoning, with special regard to the adrenal changes. COMPARATIVE ANALYSIS OF ANTIBACTERIAL EFFECT OF PHYTOANTIBIOTICS AND ANTIBIOTICS. Three-day malaria with a prolonged and short incubation period in persons arriving from the southern parts of the USSR. The testing of vaccines for use in chickens requires a large number of animal trials. A growing body of evidence suggests that reproductive history influences post-reproductive mortality. We suggest and briefly discuss various mechanisms that could contribute to this observed behavior.

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We found that lysosomal inhibition by chloroquine (CQ) could also enhance TRAIL-induced apoptosis. Kinetics of K-Cl cotransport in frog erythrocyte membrane: effect of external sodium. This is thought to reflect their poorer sensory coding abilities and their more limited experience of pictures and representations of objects. Use of sunscreen is encouraged to reduce the risk of skin pathologies caused by radiation. Prognostic impact of transurethral resection on patients irradiated for localized prostate cancer. Effect of trapping vascular endothelial growth factor-A in a murine model of dry eye with inflammatory neovascularization. The evolution of retail clinics in the United States, 2006-2012. This idea can account for diverse experimental findings, and has been hugely influential over the past two decades.

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Name No Names: The Role of the Media in Reporting Mass Shootings. Variables associated with extra uterine growth restriction in very low birth weight infants. This study compared the efficacy and tolerability of aripiprazole with that of other atypical antipsychotics by examining patients with pediatric bipolar disorder (PBD) at a child and adolescent psychiatric clinic in a university hospital in Korea. Effect of exposure to a cold environment on labeling of phospholipide in rat liver slices. In addition, Morris water maze training induced a gradual increase in levels of pro-MMP-9 and active-MMP-9, which were attenuated by 150 mg/kg propofol but not 75 mg/kg propofol treatment immediately after training. By comparison with controls and with patients suffering from Alzheimer-type dementia (in which there is also temporal horn enlargement), the change is highly significantly selective to the left hemisphere. A patient is described with nontraumatic subcapsular haematomas of both kidneys, complicated by severe retroperitoneal bleeding. This paper aims to evaluate the efficacy of an innovative structured mindfulness-based cognitive therapy (MBCT) group programme adapted for adults with ID with a diagnosis of either recurrent depression, anxiety or both clinical conditions and a history of deliberate self-harm behaviour.

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The effect of percutaneous coronary intervention of chronically totally occluded coronary arteries on left ventricular global and regional systolic function. FDA has made the determination because of the submission of an application to the Commissioner of Patents and Trademarks, Department of Commerce, for the extension of a patent which claims that medical device. Expectantly waiting: a survey of thyroid surgery wait times among Canadian otolaryngologists. Overweight status does not appear to affect treatment response in adolescents with resistant depression. This review article provides an overview of research from both clinical and supramolecular communities towards heparin binding and sensing and considers how this area may develop in the future. The purpose of this study is to report preliminary healing and complication rates of periprosthetic distal femur fractures treated with FCL constructs.

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Enhanced detection of high-mass proteins by using an active pixel detector. Altogether, these results suggest that TI-VAMP/VAMP7 defines a novel membrane compartment in neurite outgrowths and in the somatodendritic domain. Risk factors of confusion, dizziness, altered elimination, and difficulty with mobility were found to be significantly associated with fall status. Posterior dislocation of the elbow with an osteochondral fracture. We report about the case of ultram dosing one patient with diffuse small bowel metastases of melanosarcoma, which were revealed by signs of malabsorption 2 years after the exeresis of the initial skin tumor. For quality indicators to effectively guide quality improvement efforts, they must be developed, evaluated, maintained, and implemented using rigorous evidence-informed practices. Radical surgery as well as effective adjuvant therapy are required for gastric cancer with invasion of the serosa. This investigation was part of a multicenter-retrospective study in Japan (J-BIRD).

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Estimates are made for the blast radius that one can expect for a given amount of detonation energy and pyrotechnic display material. An important unsettled issue is whether filtered-out and subgrid spatial scales can significantly alter the evolution of resolved larger scales of motion and practical flow integral measures. We sought to characterize the practice of issuing do-not-resuscitate orders in intracerebral hemorrhage. The triggers of sterile inflammation are still being identified, and the pathways that transduce sterile inflammatory signals are not completely clear. Not covered by this term would be conditions necessary for prebiotic chemistry and conditions that would allow the recognition of extinct or hibernating life.

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Aging, hypertension, obesity and abnormal glucose metabolism are positive factors for inter-ankle SBP difference. Development and genetics in the evolution of land plant body plans. To identify miRNAs in eggplant and their response to Verticillium dahliae infection, a fungal best moisturizer to use with tretinoin gel pathogen for which clear understanding of infection mechanisms and effective cure methods are currently lacking, we deep-sequenced two small RNA (sRNA) libraries prepared from mock-infected and infected seedlings of eggplants. Influential factors for young broilers are ground temperature and stratification. One hundred and ninety-five patients with SLE were studied at two centres in the UK (London and Birmingham). Protecting our employees: the role of the professional nurse: Part 2. To analyze different factors affecting the outcome of patients undergoing Two Stage Esophagectomy (TSE) for the treatment of esophageal carcinoma (EC) while relating these factors to the length of stay on Intensive Care Unit (ILOS), mortality, and morbidity. Since the starting material was D,L-(adamantyl-glycine) the condensation products with the dipeptide were mixtures of diastereoisomers. Here we demonstrate a critical link between Myc/Mycn gene activity and glycolysis in SSC self-renewal. In patients with hepatitis B virus (HBV)-related HCC, a high viral load is a strong risk factor for HCC recurrence.

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Fibroblast growth factor-7 facilitates osteogenic differentiation of embryonic stem cells through the activation of ERK/Runx2 signaling. Audiologic threshold monitoring of patients receiving ototoxic drugs. The present study aimed at studying behaviour of P300 amplitude of the event-related brain potential in a frame-of-reference investigation. Antibodies against the beta 1- and beta 2-peptides were detected with an enzyme immunoassay performed in blinded manner. Early studies focused on hormone measurements in adult men and women. Body weight at diagnosis, tumour size and the presence of metastases at diagnosis were inversely related biaxin drug classification to survival. The rare cutaneous presentation consisted of mostly circumscribed, tender, tense pustules, associated with erythema, confined to the face and neck.

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Speech, hearing, and language disorders: a frame of reference for research and therapy. The results demonstrate that a well-organized cartilage matrix is required as a primary tissue for development of some components of the vertebrate skeleton, but it is not essential for others. VO2 and REE differ among groups of patients with non-SIRS, nonseptic SIRS, and septic SIRS. The works that are discussed in this paper show better drug targeting of brain when given through nasal route as nanoparticles. We combined weekly ACT stock data for the period 2009-2011 from six health facilities in the Ulanga District in Tanzania, together with household data from 333 respondents on the cost of fever care-seeking in Ulanga during the same time period to establish how health seeking behaviour and expenditure might vary depending on ACT availability in their nearest health facility. This study concurs that patients do prefer to be treated at home rather than being admitted to secondary care. Proceedings of the 5th Annual Frederick Conference on Capillary Electrophoresis. Ribozymes proved to have a higher inhibitory potential as conventional antisense constructs of comparable nucleotide sequence. Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures. Affective instability, but not impulsivity, predicted the continuation of nonsuicidal self-injury during the follow-up period.

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Evaluation of Relationships among Occupational Stress, Alcohol Dependence and Other Factors in Male Personnel in a Japanese Local Fire Fighting Organization. Obesity is associated with a high risk for atherosclerotic cardiovascular disease. As mRNA levels depend simultaneously on synthesis and degradation rates, those studies were unable to discriminate the respective roles of both arms of the equilibrium process. A microRNA encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene ODV-E25. Delays in diagnosis and treatment of breast cancer: a multinational analysis. However, the field of psychology is still making limited use of neuro-oscillatory dynamics for a bio-behavioral understanding of cognitive-affective processes. Yohimbine is an alpha-2 blocking altace generic agent which also increases cholinergic activity.

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The present review analyzes the dietary and exercise intervention studies performed to date in both altricial and precocial animals, rats and sheep, with the aim of preventing adverse offspring outcomes. Dexamethasone augmented calcitriol effects, with synergism at 0.05 and 0.1 nM dexamethasone in MCF-7 cells and 5 nM in Caov-4 ovarian cells. This finding indicates that ingested nicotine has antidepressant properties that are independent of the genetic difference between FSL and FRL female rats. In human putamen, the presynaptic markers of dopaminergic nerve terminals (neurotensin receptors, dopamine uptake sites and amine vesicular transporter-binding sites), benzodiazepine receptors and serotonin uptake sites were recovered both in the high and low density fractions, whereas the muscarinic, opiate and, to a lesser extent, dopamine D2 receptors were mostly concentrated in the microsomal fraction. Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features. The predictive performance of the model was internally validated through a two-step nonparametric bootstrapping process.

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