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We describe a patient with refractory MMN who improved with high-dose cyclophosphamide (50 mg/kg for 4 days) without stem cell rescue. The significance of the recognition of the contextual part of the sentence with respect to the recognition of the whole sentence is different in HP and LP sentences. Interaction of sugar phosphates with the catalytic site of ribulose-1,5-bisphosphate carboxylase. Some comparative measurements of impaired discrimination for sound spectral differences. Differences in adjuvant radiotherapy use related to demographic and geographic factors suggest that at least some treatment variations reflect differences in individual and institutional practice patterns. The positioning of the centrosome and the dynamic regulation that couples and uncouples the nucleus underlies directed migration of neurons. An African swine fever virus gene with a similarity to eukaryotic RNA polymerase subunit 6. In vivo neurochemical effects of electroconvulsive shock on the forced swimming rat. Ultrasound guided suprapubic puncture--a new, simple way of releasing a blocked Foley balloon. Blood parameter and heart rate response to training in Andalusian horses.
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The microcoils were used in 1H nuclear magnetic resonance (NMR) spectroscopy experiments at 300 MHz (7.05 T). The overlapping localization in vivo, the molecular binding studies, and the striking effects on neuronal adhesion and neurite growth support the view that neurocan may modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules. Cephaloridine in urinary tract infections: influence of the duration of treatment of short-term results. There was no detectable increase in plasma carotenoids after treatment in carotenoid-fed nestlings of either species despite regular supply of dietary carotenoids. However, folylpolyglutamate synthetase activity was markedly decreased in this subline using tetrahydrofolate, 5,10-methylenetetrahydrofolate, and methotrexate as substrates.
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Structural features of myelin basic protein mRNAs influence their translational efficiencies. The effect of recombinant human granulocyte colony-stimulating factor (rhG-CSF) on the recovery from neutropenia induced by fractionated whole-body irradiation was investigated in mice. Working together to respond to the challenges of EU policy to replace animal testing. We report a 3-year-old boy with AIDS and Kaposi sarcoma of the skin and lymph node. Scientific, ethical and legal aspects of the acceptance of in vitro methods in regulatory toxicology. This method has been developed to visualize structural details of the tongue surface of living human beings and laboratory animals. Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. gapperi agents had a 5-day incubation period followed by prostration and death with a histologic picture of extensive encephalomalacia. Clinical evaluation of caudal epidural anaesthesia for the neutering of alpacas.
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Functional analyses of mutations in the NF1 gene may provide further insights into the pathogenesis of NF1 tumors. Before IB therapy, only three of the nine patients were able to live at home in the community and six were institutionalized. A patient with severe disability from the bent spine syndrome was compared with a fortuitously discovered asymptomatic research subject with the syndrome, in terms of physical examination, magnetic resonance imaging, and electrodiagnostic testing. For the first six dose levels, a 4-week cycle consisted of escalating doses of cisplatin during weeks 1 and 2, IFN (week 1), and 5-FU and HU (week 2) with single daily radiation fractions of 200 cGy during days 1-5 of weeks 1-3 and no treatment in week 4. Isolated spinal cords were prepared from animals treated with NGF and were maintained in vitro for physiological and pharmacological analysis of lumbar spinal reflex activity.
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As expected, purified Aplysia Mnk phosphorylated Aplysia eIF4E at a conserved carboxy-terminal serine and over-expression of Aplysia Mnk in sensory neurons led to increased phosphorylation of endogenous eIF4E. In contrast, under UHV conditions, NO dimers were stable only at low temperatures up to 60 K, above which they transformed into a monomeric NO adsorption state with a (2x2)-3NO structure. However, long-term use of immunosuppressive drugs convey inherent risks which translate in an increase of cancers and infections, among others. The paper presents some possibilities of estimating the immunologic aggression in silicosis in a group of 68 patients divided into three subgroups according to the evolutive stage of disease. Strategies for the detection of autosomal fetal DNA sequence from maternal peripheral blood. Poly(beta(3)-hLys) was synthesized from the ring opening polymerization of the corresponding lactam. High-resolution computed tomography (CT) of the entire thorax was performed at 4 and 8 weeks after the last irradiation, and the findings with CT were correlated with hemodynamic data, heart weight, and pulmonary histopathology. Copper induces a red pigmentation in cells of the bacterium Myxococcus xanthus when they are incubated in the dark, at suboptimal growth conditions.
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She is doing well without any troubles 14 months after the reoperation. Spirometry and reversibility testing were performed on the first visit. Very recently, we reported that gefitinib reverses BCRP-mediated drug resistance by direct inhibition. The ascending aorta: how much does transesophageal echocardiography see?. Twenty-one cases of sebaceous epithelioma collected during a 5-year period were reviewed. Segmentation results of real intestinal cell gland images are provided to show the effectiveness of the proposed algorithm. Spontaneous mononucleosis caused by cytomegalovirus in the immunocompetent adult. The alpha 2-macroglobulin receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands. Development of experimental designs for atherosclerosis studies in mice. Comparison of a gonadotropin-releasing hormone agonist and a low dose oral contraceptive given alone or together in the treatment of hirsutism.
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In these cells both cytokines share overlapping binding sites, but the number of sites for IL-13 is half of that for IL-4. The seven drugs were then tested for efficacy in random order in patients who were eligible to receive them. This is the first case to describe recurrent pachymeningoencephalitis with character changes, and symptoms were probably due to frontal lobe dysfunction. It was found that the PR system gave better expression than the two other systems. The RNA-binding domain of transcription termination factor rho: isolation, characterization, and determination of sequence limits. The biological relationships among Indian groups of the Southwest. Acceleration of de novo bone formation following application of autogenous bone to particulated anorganic bovine material in vivo. Shaken baby syndrome: a biomechanics analysis of injury mechanisms. The clinical manifestations corresponded to the level of the ischemic lesion in the spinal cord and the disease course. Karyotypic characterization of human T-cell lines immortalized by Herpesvirus saimiri.
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Myocardial edema is a clinically relevant problem found in post-ischemic reperfused hearts. Lanthanide-based luminescent assays for ligand-receptor interactions. This may represent a stress-responsive compensatory mechanism in the human placenta. The reduced expression of HLA-class II antigens and adhesion molecules on monocyte surface after phagocytosis of bacteria. Sodium pentosanpolysulphate in the management of haemorrhagic cystitis: experience with 14 patients. tuberculosis DNA in CSF samples from patients with suspected TBM. Auxiliary extracorporeal shockwave lithotripsy (ESWL) was used in 2 patients whose stones could not be fragmented mechanically by the percutaneous basket technique. Serum levels of FSH, LH, E2, and P and follicle diameter by transvaginal sonography. Both cell types relaxed precontracted distal colonic circular smooth muscle in a concentration dependent manner. The nether surface of the cells showed a wrinkled and irregular undulations and did not show cilia or mv.
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Although a high Gleason score is a determinant of prostate cancer death, its PPV is relatively low. This report tries to elucidate the role played by the variable surface glycoprotein (VSG) coat and trypanosome surface-related processes in the mechanism of HS lysis of HS-sensitive (HSS) and HS-resistant (HSR) trypanosomes. Gait analysis also identified significant differences between the two groups with regard to cadence and stride length. This prediction was confirmed in a series of studies in the rat. Pseudomonas cepacia is usually resistant to several antibiotics in vitro, but the response of patients colonised with the organism has not been extensively studied in vivo. Defects in both the insulin receptor and postreceptor steps of the insulin action pathway have been reported. A transient induction was observed, with the strongest hybridization signal seen after 1.5 h and subsequent decrease to near basal levels at 3 h. The purpose of this study was to develop a general substrate of wide applicability with which variations in enzymatic activity would be minimized. Five subjects were asked to produce fast (ballistic) and slow (ramp) contractions with thumb and index finger of the right hand in a simple reaction time task. We present here the 3-dimensional structural features of mature fully active Der p 1, one of the main allergens involved in human allergic diseases.
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In each ganglion of the central nervous system of Helix pomatia, numerous CARP-immunoreactive cell bodies and a dense immunoreactive fiber system could be observed with a dominancy in the cerebral and pedal ganglia. Murine eosinophils express the low-affinity Fc gamma receptors recognized by the monoclonal antibody (mAb) 2.4G2, which are involved in the activation of these cells. The nitrosamines were determined by the TELLING method (confirmed by photolysis). Pseudosarcomatous changes in the cervix following irradiation for cervical carcinoma. In addition, the Wnt receptor, mFrizzled (mFzd)-1, the signaling mediator disheveled-1, and the transcriptional co-activator, lymphocyte enhancement factor (Lef)-1, are all increased during hypertrophy of the overloaded mouse plantaris muscle.
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A polypeptide was purified whose partial amino acid sequence demonstrated its identity to the product of the SAC1 gene. A purely intralaryngeal thyroglossal duct cyst is extremely rare and can mimic other laryngeal lesions. The amount of muscle tissue and of collagenous connective tissue has been numerically quantified. Sensitizing experiments performed with blackwood heartwood extracts corroborated the described sensitising properties. Inhibition of cAMP formation showed the opposite dependence with no effect on maximal response but an increase in EC50 value as receptor density decreased. Potential treatment for lysosomal diseases now includes enzyme replacement therapy, substrate reduction therapy, and chaperone therapy. The synthesis of NO by activated macrophages correlates with their cytotoxic effect on neoplastic cells as well as killing of intracellular parasites. Since these malignancies are usually not responsive either to radiotherapy or chemotherapy, once diagnosed, the only hope of cure lies in surgical resection.
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Nitric oxide (NO), as a free radical, seems to be a potential antioxidant. The final determination of the name must await cultivation of the fungus. The Bureau for the Prevention of Blindness is responsible for the provision of cataract surgery to the rural indigent population of South Africa. Rupture of the umbilical cord cyst and disruption of the umbilical cord occurred in one case at delivery. A ganglion cell plexus, however, was seen only in cynomolgus monkey eyes. These approaches are convenient to provide firmly established short-term evaluations of the effects of type I agents in relatively benign arrhythmias occurring in patients with good cardiac function. DNA adducts among personnel servicing and loading diesel vehicles. CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen. The association may not be coincidental as multiple microfistulae could cause abnormalities of the microcirculation and result in reactional myocardial hypertrophy. Evaluation of the structural and functional changes in the hands in rheumatoid arthritis after a 2-year rehabilitation.