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Both doses of Valium significantly decreased the incidence and severity of lesions on the endothelial surface of the aorta and coronary artery in roosters fed an atherogenic diet. These results suggested that pp150 was an immunogenic protein in natural HCMV infection and therefore this clone was regarded as a useful candidate for developing an antigen for the serodiagnosis of HCMV. Legislative bans and various forms of legalization have been proposed. We have investigated the expression pattern of these peptides in the brain and in the gut during different stages of the life cycle of the parasitic lamprey, Petromyzon marinus, and the nonparasitic lamprey, Ichthyomyzon gagei. Detection of glucocorticoids and mineralocorticoids in the kidney using a biological method. Hence, Tea1, like Rap1, is a member of a small family of downstream activators in Saccharomyces cerevisiae. Trace element survey analysis of biological materials by spark source mass spectrometry. Unlike most SH2 domain interactions that require tyrosine-phosphorylated residues, the Raf-1/Fyn SH2 domain association was dependent on the serine phosphorylation of Raf-1. These characteristics provided evidence that the Ra antigen belonged to the R proteins of GBS. To summarize the experience of diagnosis and surgical treatment of ventricular septal defect with patent ductus arteriosus.
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The expression of human thymidine kinase CCAAT-binding activity was serum or independent in human tumor cells but serum dependent in normal human diploid fibroblasts. To compare the efficacy and tolerability of clarithromycin extended-release (ER) to amoxicillin/ clavulanate in patients diagnosed with acute bacterial sinusitis. Molecules which are involved in osteoclastic bone resorption: from the aspect of targets of treatment for osteoporosis. Anodic asymmetry of leaves and flowers and its relationship to phyllotaxis. Expression, purification, crystallization and preliminary X-ray diffraction analysis of Arabidopsis thaliana cyclophilin 38 (AtCyp38). In particular, in the tail, SRC3 was not recruited in a T3-dependent manner to the target TRbetaA promoter, suggesting either no recruitment or constitutive association.
Genetic transformation in Streptococcus sanguis is a complex, multi-step process, involving several factors. Exposure of long-term cultured normal human keratinocytes to ultraviolet B (280-320 nm) or to ultraviolet A1 (340-400 nm) radiation caused a time- and dose-dependent induction of interleukin-10 mRNA expression and interleukin-10 protein secretion, with ultraviolet A1 radiation being the strongest stimulus. The adjuvant activity of pyrene in diesel exhaust on IgE antibody production in mice. The Veterinary Service is formulating a quality assurance procedure in accordance with standard EN 45004-ISO 17020, which determines the requirements that inspection bodies must follow to be recognised, at national, European and international level, as competent and reliable. Waiting for a typical abnormal EEG pattern can generate an unacceptable delay in the correct diagnosis and treatment of these patients.
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The occurrence of antibiotic resistance was compared between mastitis pathogens (Staphylococcus aureus, nonaureus staphylococci, Streptococcus dysgalactiae, Streptococcus uberis) from farms with organic and conventional dairy production. Degradation behavior of hydrophilized PLGA scaffolds prepared by melt-molding particulate-leaching method: comparison with control hydrophobic one. In cases of prolonged foot ischemia with edema and paresthesia in the toes, extended ankle and foot fasciotomy should be performed as a surgical limb-salvage procedure. Paracetamol, anthraquinone-containing preparations, and griseofulvin are examples for pharmaceuticals that have been in use for a long time but for which genotoxicity testing revealed a possible deleterious potential only recently. Polyclonal antibodies directed against an epitope specific for the alpha 4-subunit of GABAA receptors identify a 67-kDa protein in rat brain membranes. The response to lomuzol was registered in 37 out of 39 patients with allergic rhinitis given lomuzol. Among them, seven identified proteins were found significantly altered in almost all the AML blast cells analyzed in relation to normal mononuclear blood cells: alpha-enolase, RhoGDI2, annexin A10, catalase, peroxiredoxin 2, tromomyosin 3, and lipocortin 1 (annexin 1). Parathyroid hormone-related protein is produced by cultured endothelial cells: a possible role in angiogenesis. FCH is a recently recognized hamartoma of follicular, sebaceous, and mesenchymal elements.
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With this method, monoclonal and oligoclonal cell lines producing anti-HBs antibodies were established and three anti-HBs Fab antibodies were isolated from two of these cell lines. These weights are automatically assigned based on the distance of the sequences using a published procedure (Sibbald PR, Argos P, 1990, J Mol Biol 216:813-818). The breakdown of the fungicide carbendazim in an aqueous environment. In industry and traffic, vibrations present complex oscillatory motions, characterized by a wide frequency spectrum, variable amplitude and acceleration, and different directions. To determine the effect of chlorpromazine on the serum concentration-time curve and metabolism of meperidine, 10 healthy volunteers were injected on two separate days in a two-way crossover design with 26 mg/m2 meperidine hydrochloride combined with either 30 mg/m2 chlorpromazine or a placebo. A new method of multisegment motor pathway monitoring using muscle potentials after train spinal stimulation. Laryngeal collapse is relatively common in dogs presented for surgical correction of brachycephalic airway obstructive disease. When cells cultured with juniperonic acid (20:4, delta-5c,11c,14c,17c) were stimulated, 1-stearoyl-2-juniperonoyl-G was produced in proportion to the level of this molecular species in PI in the cells. We have previously described a recombinant baculovirus BVCEA-140 expressing the full-length human CEA and a variant, BVCEA-16, that encodes only the NH2-terminal domain, as well as a recombinant (BVNCA) expressing the closely related molecule nonspecific cross-reactive antigen (NCA).
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Antibodies were present in patients without the use of bone allografts, indicating that OA patients develop antibodies to bone soluble proteins. It was demonstrated that normal lung could proliferate in agar with similar plating efficiencies to fresh tumours and that fibroblastic cells were present in these cultures. The insolubilization was associated primarily with loss of gamma crystallin fraction of the soluble proteins. This study demonstrated that the HiMAT is a reliable tool for measuring high-level mobility. To assess facial deformities in uremic conditions and to understand the possible relation with hyperparathyroidism, the three-dimensional coordinates of 50 soft tissue facial landmarks were obtained by an electromagnetic digitizer in 10 male and 10 female patients (aged 53-81 years) with chronic renal insufficiency and regular dialysis treatment. The authors describe the opposition and their strategies, and how, in hindsight, the campaign might have been better managed. Thyroid-releasing hormone did not change the survival rate, serum amylase, glucose calcium, liver transaminases levels or the degree of pancreatic damage, but reduced lactate dehydrogenase. Furthermore, the xenoestrogens, 4-nonylphenol and bisphenol A, were shown to promote ER dimerization in the yeast two-hybrid system. The effect is seen at the restrictive temperature but not at the permissive temperature. Enhancement of the chemical semantic web through the use of InChI identifiers.
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Increased T cell activation in patients with ANCA-associated vasculitis in remission during and after immunosuppressive treatment is associated with persistent or renewed ANCA positivity. Taken together, these results suggest that most clustered glucocorticoid receptor molecules are not directly involved in activation of transcription. Targeting TIRC7 with monoclonal antibody might serve as a promising therapeutic strategy for preventing allograft rejection in humans and treatment of other immune-related diseases. Computed tomography revealed an esophageal tumor invading the left atrium and aorta, and multiple intrathoracic lymph node swellings, and an ultrasonograph of the liver showed multiple liver metastases. The discovery of novel, structurally diverse protein kinase C agonists through computer 3D-database pharmacophore search. The UV dose was increased at each treatment session according to the erythematous response to the previous treatment. A plot of cytotoxicity versus SCEs indicated a good correlation between these two parameters for topoisomerase II inhibitors and not for mytomicin C. Using a proteomic approach, we have identified several potentially new cargoes for Kap114p.
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Detection of specific antibodies to Neospora caninum and Toxoplasma gondii in naturally infected alpacas (Lama pacos), llamas (Lama glama) and vicunas (Lama vicugna) from Peru and Germany. The serological response was compared with the microbiologic and histologic studies of biopsy samples from 4 locations in each patient: duodenal bulb, gastric antrum, corpus and fundus. We made a biochemical study of four perineuronal antigens on different subsets of rat brain neurons and found that three antigens recognized by antibodies against glycosaminoglycan epitopes were large proteoglycans. New surgical technique for treatment of stress urinary incontinence TVT-Obturator: new developments and results. Also pheochromocytoma cells synthesize and express D2 receptors. These findings will be useful in designing clinical trials of vanadyl sulfate for diabetic subjects.
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The swelling of the hydrated PPPMA films in humid air is reversible. Genetic redirection of lymphocytes that have been genetically engineered to recognize antigens other than those originally programmed in their germlines is a potentially powerful tool for immunotherapy of cancers and potentially also of persistent viral infections. At the low doses of rhNGF, 10 and 30 micrograms/ml, a small area of the irides was reinnervated and the density of the nerve fiber network was low. A method for the bacteriological analysis of sewage and surface water polluted by sewage. Protecting the endothelium of normal tissues, such as the lungs, from the toxic effects of current antineoplastic agents and the destruction of the tumor vasculature are reasonable goals. Cholinergic neurons in the ventral trapezoid nucleus project to the cochlear nuclei in the rat. Timely recognition of this rare but potentially fatal drug reaction is important. Therefore A2 receptor activation is not essential for the induction of LTP when stronger tetani are applied. KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions. Antibody production to the novel antigen keyhole limpet hemocyanin was assessed over the 4-week treatment period.
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The extent to which the number of involuntary admissions changed after implementation of the BOPZ was examined by means of Poisson regression on the basis of national data from the Patient Registration of Intramural Mental Healthcare for the period 1979-1995 and data from the Healthcare Inspectorate for the period 1992-2004. Even though various techniques for site-directed mutagenesis have been developed, random mutagenesis is an important and complementary approach to locate functional domains on polypeptides and RNA, and to modify their biochemical and biological properties. The reduced thermal mass of microchips allows for extremely fast temperature ramping. The understanding of both of these aspects is still evolving and impacts significantly on the ongoing clinical determinants of success. Unchecked DNA synthesis and blocked cell division induced by methionine deprivation in a human prostate cancer cell line. A model to predict carboxyhemoglobin and pulmonary parameters after exposure to O2, CO2, and CO. Progressive ultrastructural changes in the mucosal epithelium of the small intestine of beagle dogs fed methoxychlor. The notion that safety may be improved by operating with the patient in the supine position was not confirmed.
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There were regular opportunities through nurses and consultations with general practitioners for continuing advice about risk factors. Behavioral approaches are now well represented in the practice of clinical social work, and this trend is seen as likely to continue to expand. An excellent staining method to demonstrate in vivo dermatophytes and DNA-synthesizing cells in the skin is described. Health of workmen in the chromate-producing industry in Britain. The control of rotational instability after intramedullary nailing for femoral shaft fractures in adults. Recent evidence suggests that natural autoantibodies may play an integral role in the development of the normal immune repertoire.
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