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As this side of the molecule consists of residues from both the N- and C-terminal domain, it seems unlikely that agonists or antagonists can be developed on the basis of short peptides taken from the primary sequence. Mucosal perfusion and reactivity of the rat small intestinal allograft. The corneal contact lens electrode, because of its convenience, has replaced the cotton-wick electrode for recording electroretinograms from patients and animals such as dogs, rabbits, and cats. Pronounced differences in occurrence and numbers of T cells recognizing MBP, MBP peptides with the amino acid sequences 63-88, 110-128 and 148-165, and PLP were noticed in individual ON and MS patients over the course of disease. Although many of these structures appear to be refractory to removal by reverse cholesterol transport mechanisms, they may possess functional properties that still need to be elucidated. A high degree of conservation with other members of the parvulin family was revealed in the structure and binding site. However, the effects of early-glycated proteins, such as glycated serum albumin (Gly-BSA), are poorly defined. Myocardial contractility, and the effects of beta-adrenergic blockade in hypothyroidism and hyperthyroidism. Some genetic-biochemical systems involved in differentiation of groups of animals with respect to characteristics of milk production were revealed.
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Macular flecks in Alport syndrome are not associated with demonstrable retinal dysfunction. Tumour cells with phagocytic ability were used as the in vitro test system. Clot formation, arteriovenous fistula compression time and residual volume of filters were similar for both types of heparin. On the hemodynamics of pulmonary circulation in ductus arteriosus persistens (DAP). Environmental factors influence the rate of human herpesvirus type 8 infection in a population with high incidence of classic Kaposi sarcoma. Failure of guanethidine or desipramine to inhibit this effect of dopamine ruled out mediation by endogenous noradrenaline. Report of a case and immunohistochemical study of keratin expression. Causes of insufficient effectiveness of collagen plasty (an experimental study).
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Lead discovery is a complex process that is intimately linked to chemistry, but which is also increasingly driven by biological sciences. Temporal integration: amount of reward and relative utility of immediate and delayed outcomes. Thus, academic medical centers are faced with successive waves in information technology use. First, switching between multimodal coordination patterns occurred, with transitions selecting one multimodal pattern (flexion with sound and extension with touch) more often than its partner. Serum cortisol levels were determined in the patients at 18.00, 02.00 and 08.00 hours. This was achieved using the approximation of excluded coions if the absolute value of the reduced Donnan potential is larger than 2 and due to the simplification in the case of weak dissociation, when the absolute value of the reduced Donnan potential is less than 2.
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After excluding stillbirths with major cerebral malformations, the brains of 175 cases and the corresponding placentas in 165 cases were available for assessment. Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family. Adding levamisole to the PHA cultures also produced some antihistaminic effect. Human estrogen sulfotransferase gene (STE): cloning, structure, and chromosomal localization. Nebulin, a giant myofibrillar protein with size variants from 700 to 900 kDa in various skeletal muscles, has been proposed to constitute a set of inextensible filaments anchored at the Z-line and coextensive with actin filaments. There were no significant changes in BAER wave amplitudes at any of the click rates on any day. Residue analysis for halofuginone in sturgeon muscle by immunoaffinity cleanup and liquid chromatography. Most of the immunoreactive product was localized in neuronal processes.
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We report characterization of an IgM monoclonal antibody (5B4/H3), which recognized a surface antigen of approximately 130 kD unique to ciliated cells. This paper outlines the known sites of caffeine activity in the body,and discusses these with respect to the effects of caffeine observed during performance assessments. The role-playing with dolls in psychotherapy (of adults and children). When administered with naloxone, substance P(1-7) produced hyperalgesia 5 and 10 min after injection, which was inhibited by dizocilpine (MK-801), a phencyclidine ligand and non-competitive antagonist of N-methyl-D-aspartate. Micrometastasis was detected immunohistochemically using an anticytokeratin antibody.
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Structural analysis reveals unusual features that distinguish it from other inverted repeat transposons, whereas many aspects are similar to the widely distributed Tc1 element of C. The Aga Khan University Hospital, Karachi from March 2003 to May 2003. In order to investigate further the role of testicular macrophages after massive Leydig cell death, adult rats were injected intra-testicularly with liposome-entrapped dichloromethylene diphosphonate (Cl2MDP-lp, right testis) to deplete testicular macrophages, and with NaCl (left testis) as control. Hypothyroidism associated with mixed connective tissue disease and its response to steroid therapy. Marked renal conservation of sodium and water was present in a number of apparently healthy ileostomy patients. Retrospective, observational cohort study of 3682 Michigan Medicaid-enrolled children aged 6 years or younger who had a screening blood lead level of at least 10 microg/dL (0.48 micromol/L) between January 1, 2002, and June 30, 2003.
The identification of pretreatment markers with predictive significance for the presence of lymph node metastases and treatment outcome in low stage cancer of the uterine cervix is clinically important. Treatment and prognosis in malignant hypertension: clinical follow-up study of 93 patients on modern medical treatment. Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. We first evaluate the functional relationship between two genes from three different perspectives--phylogenetic profile analysis, gene neighborhood analysis and Gene Ontology assignments. The results indicate that the grade of bronchial impairment was higher in MAC than in M.
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At stage 28, some cells with few membrane-bound secretory granules, 70-90 nm in diameter, and immunoreactive with anti-frog PRL and other cells with few secretory granules, 80-110 nm in diameter, and immunoreactive with anti-frog GH are present. The functional capacity of surfactant protein D to agglutinate bacteria was impaired by oxidation. However, long term problems remain to be addressed, such as ingrowth by tumor, food impaction, and limitation of stent expansion by tumor rigidity. The effect of season of the year on the characteristics and composition of dog semen. After constriction of an aortic segment to a steady-state level of tension with ET-1, a flash of UV light induced a transient decrease in tension that returned exponentially to equilibrium. A number of indices of renal function were assessed in all subjects and a qualitative study of proteinuria carried out. Raytide phosphatase activity was inhibited by potassium fluoride, sodium molybdate, and sodium orthovanadate and was found to exist in some mycoplasmas. Alterations in configuration affect vascular injury and neointimal hyperplasia, while surface material plays a greater role in thrombosis. These molecules mediate short-term (acute) signaling functions in neurotransmission, mechanosensory transduction, secretion and vasodilatation, and long-term (chronic) signaling functions in cell proliferation, differentiation, and death involved in development and regeneration.
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The nucleotide sequence of EGP1 predicts a leucine-rich repeat protein that is similar to Sds22, a protein from the fission yeast Schizosaccharomyces pombe that positively modulates PP1. Persistent activation of the ANG/Tie-2 system in addition to high levels of VEGF may keep the vasculature in a destabilized condition and may account for the continuous formation of new and immature blood vessels resulting in massive plasma extravasation and repeated bleeding episodes. Intravenous (i.v.) iron is employed to treat absolute and relative iron deficiency in end-stage renal disease patients. Evaluation of chlorothiazide alone in the treatment of moderately severe and severe hypertension. Chronic granulomatous disease (CGD) is characterized by life-threatening bacterial and fungal infections. Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development. These results suggest that blood flow in the superior and inferior mesenteric veins can be found mixed in the liver in most subjects with liver disease. Effect of chlorophyll derivative and metal complexes on pancreatic lipase activity. Analgesic properties of 4-ethoxycarbonyl-1-(2-hydroxy-3-phenoxypropyl) 4-phenylpiperidine (B.D.H. In this study, we demonstrate that the violation of this assumption may lead to serious bias in haplotype frequency estimates, and haplotype association analysis based on this assumption can induce both false-positive and false-negative evidence of association.
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Adenoviral particles as well as viral intranuclear inclusions were noted in pulmonary alveolar epithelium cells. This affects the clinical interpretation of an early negative test result and encourages the use of PCR as an endpoint for trials to evaluate interventions to reduce vertical transmission in non-breastfed populations. Surgical treatment of congenital megacolon in childhood by the Swenson-Hiatt technic. Patient compliance with follow-up, the specific expertise of the physicians, and the availability of specialized therapeutic care ultimately may influence such decisions. Increase of conjugated dienes was proportional to vitamin D3 concentration. Using polymerase chain reaction (PCR) techniques, we determined the frequency of occurrence and the proportion of mtDNA with the 4977-bp deletion in human spermatozoa with different motilities. As survey reports two kinds of computer forms are produced: an individual message where each laboratory results are compared with the others through a DI, an yearly message with the DI evolution.